ID KCTD6_HUMAN Reviewed; 237 AA. AC Q8NC69; B3KNI5; Q8NBS6; Q8TCA6; DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot. DT 03-OCT-2006, sequence version 2. DT 01-OCT-2014, entry version 84. DE RecName: Full=BTB/POZ domain-containing protein KCTD6; GN Name=KCTD6; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RX PubMed=14702039; DOI=10.1038/ng1285; RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S., RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.; RT "Complete sequencing and characterization of 21,243 full-length human RT cDNAs."; RL Nat. Genet. 36:40-45(2004). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RX PubMed=16303743; DOI=10.1093/dnares/12.2.117; RA Otsuki T., Ota T., Nishikawa T., Hayashi K., Suzuki Y., Yamamoto J., RA Wakamatsu A., Kimura K., Sakamoto K., Hatano N., Kawai Y., Ishii S., RA Saito K., Kojima S., Sugiyama T., Ono T., Okano K., Yoshikawa Y., RA Aotsuka S., Sasaki N., Hattori A., Okumura K., Nagai K., Sugano S., RA Isogai T.; RT "Signal sequence and keyword trap in silico for selection of full- RT length human cDNAs encoding secretion or membrane proteins from oligo- RT capped cDNA libraries."; RL DNA Res. 12:117-126(2005). RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., RA Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., RA Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., RA Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R., RA Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., RA Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., RA Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., RA Venter J.C.; RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases. RN [4] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Lung; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). CC -!- SIMILARITY: Contains 1 BTB (POZ) domain. {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AK027572; BAG51347.1; -; mRNA. DR EMBL; AK074934; BAC11301.1; -; mRNA. DR EMBL; AK075297; BAC11531.1; -; mRNA. DR EMBL; CH471055; EAW65374.1; -; Genomic_DNA. DR EMBL; BC022893; AAH22893.2; -; mRNA. DR CCDS; CCDS2891.1; -. DR RefSeq; NP_001121686.1; NM_001128214.1. DR RefSeq; NP_699162.3; NM_153331.3. DR RefSeq; XP_005264994.1; XM_005264937.1. DR RefSeq; XP_006713077.1; XM_006713014.1. DR UniGene; Hs.13982; -. DR ProteinModelPortal; Q8NC69; -. DR SMR; Q8NC69; 14-107. DR BioGrid; 128350; 7. DR IntAct; Q8NC69; 1. DR PhosphoSite; Q8NC69; -. DR DMDM; 115502243; -. DR MaxQB; Q8NC69; -. DR PaxDb; Q8NC69; -. DR PRIDE; Q8NC69; -. DR DNASU; 200845; -. DR Ensembl; ENST00000355076; ENSP00000347188; ENSG00000168301. DR Ensembl; ENST00000404589; ENSP00000384948; ENSG00000168301. DR Ensembl; ENST00000490264; ENSP00000417490; ENSG00000168301. DR GeneID; 200845; -. DR KEGG; hsa:200845; -. DR UCSC; uc003dkj.4; human. DR CTD; 200845; -. DR GeneCards; GC03P058452; -. DR HGNC; HGNC:22235; KCTD6. DR HPA; HPA036100; -. DR HPA; HPA036101; -. DR neXtProt; NX_Q8NC69; -. DR PharmGKB; PA134918095; -. DR eggNOG; NOG256004; -. DR HOGENOM; HOG000236287; -. DR HOVERGEN; HBG080695; -. DR InParanoid; Q8NC69; -. DR OMA; DNGDWGH; -. DR OrthoDB; EOG7M6D81; -. DR PhylomeDB; Q8NC69; -. DR TreeFam; TF315332; -. DR GenomeRNAi; 200845; -. DR NextBio; 89985; -. DR PRO; PR:Q8NC69; -. DR ArrayExpress; Q8NC69; -. DR Bgee; Q8NC69; -. DR CleanEx; HS_KCTD6; -. DR Genevestigator; Q8NC69; -. DR GO; GO:0030506; F:ankyrin binding; IDA:MGI. DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro. DR Gene3D; 3.30.710.10; -; 1. DR InterPro; IPR000210; BTB/POZ-like. DR InterPro; IPR011333; BTB/POZ_fold. DR InterPro; IPR003131; T1-type_BTB. DR Pfam; PF02214; BTB_2; 1. DR SMART; SM00225; BTB; 1. DR SUPFAM; SSF54695; SSF54695; 1. PE 2: Evidence at transcript level; KW Complete proteome; Reference proteome. FT CHAIN 1 237 BTB/POZ domain-containing protein KCTD6. FT /FTId=PRO_0000251248. FT DOMAIN 12 81 BTB. FT CONFLICT 49 49 A -> T (in Ref. 2; BAC11531). FT {ECO:0000305}. FT CONFLICT 59 59 D -> N (in Ref. 2; BAC11531). FT {ECO:0000305}. SQ SEQUENCE 237 AA; 27610 MW; 6358D9993DD060ED CRC64; MDNGDWGYMM TDPVTLNVGG HLYTTSLTTL TRYPDSMLGA MFGGDFPTAR DPQGNYFIDR DGPLFRYVLN FLRTSELTLP LDFKEFDLLR KEADFYQIEP LIQCLNDPKP LYPMDTFEEV VELSSTRKLS KYSNPVAVII TQLTITTKVH SLLEGISNYF TKWNKHMMDT RDCQVSFTFG PCDYHQEVSL RVHLMEYITK QGFTIRNTRV HHMSERANEN TVEHNWTFCR LARKTDD //