ID CL076_HUMAN Reviewed; 135 AA. AC Q8N812; DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot. DT 01-OCT-2002, sequence version 1. DT 01-OCT-2014, entry version 73. DE RecName: Full=Uncharacterized protein C12orf76; GN Name=C12orf76; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Testis; RX PubMed=14702039; DOI=10.1038/ng1285; RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S., RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., RA Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., RA Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., RA Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., RA Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., RA Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., RA Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., RA Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., RA Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., RA Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., RA Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., RA Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., RA Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., RA Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., RA Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., RA Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., RA Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., RA Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., RA Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., RA Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.; RT "Complete sequencing and characterization of 21,243 full-length human RT cDNAs."; RL Nat. Genet. 36:40-45(2004). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Brain; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). RN [3] RP VARIANT [LARGE SCALE ANALYSIS] THR-26. RX PubMed=16959974; DOI=10.1126/science.1133427; RA Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., RA Mandelker D., Leary R.J., Ptak J., Silliman N., Szabo S., RA Buckhaults P., Farrell C., Meeh P., Markowitz S.D., Willis J., RA Dawson D., Willson J.K.V., Gazdar A.F., Hartigan J., Wu L., Liu C., RA Parmigiani G., Park B.H., Bachman K.E., Papadopoulos N., RA Vogelstein B., Kinzler K.W., Velculescu V.E.; RT "The consensus coding sequences of human breast and colorectal RT cancers."; RL Science 314:268-274(2006). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AK097461; BAC05063.1; -; mRNA. DR EMBL; BC133010; AAI33011.1; -; mRNA. DR EMBL; BC133012; AAI33013.1; -; mRNA. DR CCDS; CCDS9141.1; -. DR RefSeq; NP_997318.1; NM_207435.1. DR RefSeq; XP_006719459.1; XM_006719396.1. DR UniGene; Hs.44817; -. DR ProteinModelPortal; Q8N812; -. DR IntAct; Q8N812; 2. DR PaxDb; Q8N812; -. DR PRIDE; Q8N812; -. DR Ensembl; ENST00000309050; ENSP00000308368; ENSG00000174456. DR GeneID; 400073; -. DR KEGG; hsa:400073; -. DR UCSC; uc001tqd.1; human. DR CTD; 400073; -. DR GeneCards; GC12M110478; -. DR H-InvDB; HIX0021190; -. DR HGNC; HGNC:33790; C12orf76. DR HPA; HPA039713; -. DR neXtProt; NX_Q8N812; -. DR PharmGKB; PA165512406; -. DR eggNOG; NOG67907; -. DR HOGENOM; HOG000111776; -. DR InParanoid; Q8N812; -. DR OMA; GNSAREW; -. DR PhylomeDB; Q8N812; -. DR TreeFam; TF342372; -. DR GenomeRNAi; 400073; -. DR NextBio; 105780; -. DR ArrayExpress; Q8N812; -. DR Bgee; Q8N812; -. DR Genevestigator; Q8N812; -. PE 2: Evidence at transcript level; KW Complete proteome; Polymorphism; Reference proteome. FT CHAIN 1 135 Uncharacterized protein C12orf76. FT /FTId=PRO_0000325799. FT VARIANT 26 26 A -> T (in a colorectal cancer sample; FT somatic mutation). FT {ECO:0000269|PubMed:16959974}. FT /FTId=VAR_039916. SQ SEQUENCE 135 AA; 14959 MW; 42A798DE2376F0B3 CRC64; MFQNLQGTFE KEIGKIIPFT IAFKRAEAVE PDGCVQSWRC CLPCDLGQAS RFIHTTVCSA IRWRSCKGER NFAERHILPA ELEEQSNHAG MGPILPAMPS VDGNHFQHPA GDCHPYGILC LQAHSASVTA RQVLQ //