ID Q8MY87_HEMPU Unreviewed; 250 AA. AC Q8MY87; DT 01-OCT-2002, integrated into UniProtKB/TrEMBL. DT 01-OCT-2002, sequence version 1. DT 24-JAN-2024, entry version 77. DE RecName: Full=TATA-box-binding protein {ECO:0000256|ARBA:ARBA00021962}; DE AltName: Full=TATA sequence-binding protein {ECO:0000256|ARBA:ARBA00030739}; DE AltName: Full=TATA-binding factor {ECO:0000256|ARBA:ARBA00042653}; DE AltName: Full=TATA-box factor {ECO:0000256|ARBA:ARBA00033017}; DE AltName: Full=Transcription initiation factor TFIID TBP subunit {ECO:0000256|ARBA:ARBA00042691}; GN Name=TBP {ECO:0000313|EMBL:BAB92075.1}; OS Hemicentrotus pulcherrimus (Sea urchin) (Strongylocentrotus pulcherrimus). OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea; OC Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae; OC Hemicentrotus. OX NCBI_TaxID=7650 {ECO:0000313|EMBL:BAB92075.1}; RN [1] {ECO:0000313|EMBL:BAB92075.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=12136085; DOI=10.1093/nar/gkf439; RA Kobayashi A., Akasaka K., Kawaichi M., Kokubo T.; RT "Functional interaction between TATA and upstream CACGTG elements regulates RT the temporally specific expression of Otx mRNAs during early embryogenesis RT of the sea urchin, Hemicentrotus pulcherrimus."; RL Nucleic Acids Res. 30:3034-3044(2002). CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}. CC -!- SIMILARITY: Belongs to the TBP family. {ECO:0000256|ARBA:ARBA00005560}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB074420; BAB92075.1; -; mRNA. DR AlphaFoldDB; Q8MY87; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW. DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro. DR CDD; cd04516; TBP_eukaryotes; 1. DR Gene3D; 3.30.310.10; TATA-Binding Protein; 2. DR HAMAP; MF_00408; TATA_bind_prot_arch; 1. DR InterPro; IPR000814; TBP. DR InterPro; IPR030491; TBP_CS. DR InterPro; IPR012295; TBP_dom_sf. DR InterPro; IPR033710; TBP_eukaryotic. DR PANTHER; PTHR10126:SF42; RT01008P-RELATED; 1. DR PANTHER; PTHR10126; TATA-BOX BINDING PROTEIN; 1. DR Pfam; PF00352; TBP; 2. DR PRINTS; PR00686; TIFACTORIID. DR SUPFAM; SSF55945; TATA-box binding protein-like; 2. DR PROSITE; PS00351; TFIID; 1. PE 2: Evidence at transcript level; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125}; KW Nucleus {ECO:0000256|ARBA:ARBA00023242}; KW Repeat {ECO:0000256|ARBA:ARBA00022737}; KW Transcription {ECO:0000256|ARBA:ARBA00023163}. FT REGION 1..28 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 250 AA; 27376 MW; 3E5654EEE14D4F16 CRC64; MDNQDGGQQR SHYPQISSQQ SQSYLSVPSI GTPSFGSVGS VSSLAPGSSF IPPSPMAPLT PATPASSESS GIVPQLQNIV STVNLNCRLD LKKIALHARN AEYNPKRFAA VIMRIREPRT TALIFSSGKM VCTGAKSEDD SRLAARKYAR VVQKLGFAAK FLDFKIQNMV GSCDVKFPIR LEGLVLTHGQ FSSYEPELFP GLIYRMVKPR IVLLIFVSGK VVLTGAKVRQ EIYDAFNNIY PILKSFKKTS //