ID Q8MY87_HEMPU Unreviewed; 250 AA. AC Q8MY87; DT 01-OCT-2002, integrated into UniProtKB/TrEMBL. DT 01-OCT-2002, sequence version 1. DT 03-OCT-2012, entry version 50. DE RecName: Full=TATA-box-binding protein; DE AltName: Full=Box A-binding protein; DE AltName: Full=TATA sequence-binding protein; DE AltName: Full=TATA-box factor; GN Name=TBP; Synonyms=tbp; OS Hemicentrotus pulcherrimus (Sea urchin) (Strongylocentrotus OS pulcherrimus). OC Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; OC Echinoidea; Euechinoidea; Echinacea; Echinoida; Strongylocentrotidae; OC Hemicentrotus. OX NCBI_TaxID=7650; RN [1] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=22131754; PubMed=12136085; DOI=10.1093/nar/gkf439; RA Kobayashi A., Akasaka K., Kawaichi M., Kokubo T.; RT "Functional interaction between TATA and upstream CACGTG elements RT regulates the temporally specific expression of Otx mRNAs during early RT embryogenesis of the sea urchin, Hemicentrotus pulcherrimus."; RL Nucleic Acids Res. 30:3034-3044(2002). CC -!- FUNCTION: General factor that plays a role in the activation of CC archaeal genes transcribed by RNA polymerase. Binds specifically CC to the TATA box promoter element which lies close to the position CC of transcription initiation (By similarity). CC -!- SIMILARITY: Belongs to the TBP family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AB074420; BAB92075.1; -; mRNA. DR HSSP; P20226; 1TGH. DR ProteinModelPortal; Q8MY87; -. DR SMR; Q8MY87; 67-249. DR GO; GO:0003677; F:DNA binding; IEA:InterPro. DR GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. DR GO; GO:0006367; P:transcription initiation from RNA polymerase II promoter; IEA:InterPro. DR Gene3D; G3DSA:3.30.310.10; b_Adaptin_TBP_C; 2. DR HAMAP; MF_00408; TATA_bind_prot_arch; 1; -. DR InterPro; IPR012295; Beta2_adaptin/TBP_C_dom. DR InterPro; IPR000814; TBP. DR PANTHER; PTHR10126; PTHR10126; 1. DR Pfam; PF00352; TBP; 2. DR PRINTS; PR00686; TIFACTORIID. DR PROSITE; PS00351; TFIID; 2. PE 2: Evidence at transcript level; KW DNA-binding; Repeat; Transcription; Transcription regulation. FT REPEAT 76 152 1 (By similarity). FT REPEAT 166 243 2 (By similarity). SQ SEQUENCE 250 AA; 27376 MW; 3E5654EEE14D4F16 CRC64; MDNQDGGQQR SHYPQISSQQ SQSYLSVPSI GTPSFGSVGS VSSLAPGSSF IPPSPMAPLT PATPASSESS GIVPQLQNIV STVNLNCRLD LKKIALHARN AEYNPKRFAA VIMRIREPRT TALIFSSGKM VCTGAKSEDD SRLAARKYAR VVQKLGFAAK FLDFKIQNMV GSCDVKFPIR LEGLVLTHGQ FSSYEPELFP GLIYRMVKPR IVLLIFVSGK VVLTGAKVRQ EIYDAFNNIY PILKSFKKTS //