ID Q8MR99_DROME Unreviewed; 314 AA. AC Q8MR99; DT 01-OCT-2002, integrated into UniProtKB/TrEMBL. DT 01-OCT-2002, sequence version 1. DT 24-JUL-2024, entry version 76. DE SubName: Full=RH36510p {ECO:0000313|EMBL:AAM52031.1}; GN Name=abo {ECO:0000313|EMBL:AAM52031.1, GN ECO:0000313|FlyBase:FBgn0000018}; GN ORFNames=CG6093 {ECO:0000313|FlyBase:FBgn0000018}; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; OC Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227 {ECO:0000313|EMBL:AAM52031.1}; RN [1] {ECO:0000313|EMBL:AAM52031.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Berkeley {ECO:0000313|EMBL:AAM52031.1}; RA Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., RA Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., RA Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A., RA Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., RA Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S.; RL Submitted (JUN-2002) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY121704; AAM52031.1; -; mRNA. DR AlphaFoldDB; Q8MR99; -. DR AGR; FB:FBgn0000018; -. DR FlyBase; FBgn0000018; abo. DR VEuPathDB; VectorBase:FBgn0000018; -. DR HOGENOM; CLU_036725_1_0_1; -. DR ExpressionAtlas; Q8MR99; baseline and differential. DR GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IBA:GO_Central. DR GO; GO:0005634; C:nucleus; IDA:FlyBase. DR GO; GO:0005700; C:polytene chromosome; IDA:FlyBase. DR GO; GO:0003682; F:chromatin binding; IDA:FlyBase. DR GO; GO:0031625; F:ubiquitin protein ligase binding; IBA:GO_Central. DR GO; GO:1990756; F:ubiquitin-like ligase-substrate adaptor activity; IBA:GO_Central. DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IMP:FlyBase. DR GO; GO:0048477; P:oogenesis; IMP:FlyBase. DR GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IBA:GO_Central. DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central. DR InterPro; IPR019138; De-etiolated_protein_1_Det1. DR PANTHER; PTHR13374:SF3; DET1 HOMOLOG; 1. DR PANTHER; PTHR13374; DET1 HOMOLOG DE-ETIOLATED-1 HOMOLOG; 1. DR Pfam; PF09737; Det1; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 314 AA; 35978 MW; 58AB73AC28C3E3D1 CRC64; MAYKKRLQSQ NLVHLLQNRE SGYTNVGQQP GRMPLLAYER LFYKCITPCL TIDSITIPPI YLRKFTPDGR KLLAFSQDQR SLLIYSYGGS SCAAVGELIR QADVGSGECF SSQDTTLKSR IFERLFPTKE TLNLCQGDFG LYYLHREFSV FLEEGRYAML AAMTVVRGAL PVDDYVRYPD LFDKVDAFSY VFFLVDLKLG VVTDRLILPN DSIVIAHNHG ISVFGSTVMM MSRLHQCVYV YWVNDGKFHQ QETIGPRPRD FIEKATTDFD NLDATTVLPI THIKQRVLSF LYRKINDKSG NPTESQKSFY KNFE //