ID Q8MLW7_DROME Unreviewed; 506 AA. AC Q8MLW7; DT 01-OCT-2002, integrated into UniProtKB/TrEMBL. DT 30-NOV-2010, sequence version 3. DT 31-MAY-2011, entry version 76. DE SubName: Full=X box binding protein-1; DE Flags: Fragment; GN Name=Xbp1; ORFNames=Dmel_CG9415; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=22426069; PubMed=12537572; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX MEDLINE=20196006; PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., RA Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., RA Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., RA Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). CC -!- SIMILARITY: Belongs to the bZIP family. CC -!- SIMILARITY: Contains 1 bZIP domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE013599; AAM70855.3; -; Genomic_DNA. DR RefSeq; NP_726032.3; NM_166427.3. DR UniGene; Dm.1850; -. DR ProteinModelPortal; Q8MLW7; -. DR IntAct; Q8MLW7; 23. DR GeneID; 44226; -. DR KEGG; dme:Dmel_CG9415; -. DR CTD; 44226; -. DR FlyBase; FBgn0021872; Xbp1. DR OrthoDB; EOG4NVX2J; -. DR Bgee; Q8MLW7; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW. DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro. DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro. DR GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. DR GO; GO:0016563; F:transcription activator activity; IDA:FlyBase. DR GO; GO:0022416; P:bristle development; IMP:FlyBase. DR GO; GO:0030968; P:endoplasmic reticulum unfolded protein response; IDA:FlyBase. DR GO; GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. DR GO; GO:0035220; P:wing disc development; IMP:FlyBase. DR InterPro; IPR011700; bZIP_2. DR InterPro; IPR004827; TF_bZIP. DR Pfam; PF07716; bZIP_2; 1. DR SMART; SM00338; BRLZ; 1. DR PROSITE; PS50217; BZIP; 1. DR PROSITE; PS00036; BZIP_BASIC; 1. PE 3: Inferred from homology; KW Complete proteome; DNA-binding; Nucleus. FT NON_TER 506 506 SQ SEQUENCE 506 AA; 54970 MW; E688521EA2B0B7C6 CRC64; MAPTANTVLI TVPRTAITSN NLPKLRPAPL TAALLKVSAT PSASPTPSSS GYASSSNMDD DNMAASQPKA KKRRLDHLTW EEKVQRKKLK NRVAAQTSRD RKKARMEEMD YEIKELTDRT EILQNKCDSL QAINESLLAK NHKLDSELEL LRQELAELKQ QQQHNTRCIS QSNASAGAEG CASTNLGSAA SKADPLPQGI QQVDTQSSAR LLAEQLKSSK SLASLWKVVA LCLLYKTCLA STKSSTSSAS KSWPKVCSQI SQQTWKQALE RAAQLLPKMQ ATQSDCLDQW WGPQQSAWNP TGIELMALNV EQEQETEHKV SLNVQMLKIN GNPQHTTAAP ASRTATITAT AAASQLQATP DTVYGTYDAK TNSITIVMDG DAVPVNEAVE EIYCDGVSAG DDSTDVIMKC PPPATSPSQV YLNVMNAVDN SDDEESFDPI DRFLRPRVKA ISPLAKSPAL SLHSATSDHG YESILGSPTS VALTLPADED DFPWESNFDE LFPSLI //