ID Q8LT24_9VIRU Unreviewed; 124 AA. AC Q8LT24; DT 01-OCT-2002, integrated into UniProtKB/TrEMBL. DT 01-OCT-2002, sequence version 1. DT 07-OCT-2020, entry version 88. DE SubName: Full=Cholera toxin B subunit {ECO:0000313|EMBL:AEB78280.1}; DE SubName: Full=Cholera toxin subunit B {ECO:0000313|EMBL:ACT83406.1}; DE SubName: Full=CtxB {ECO:0000313|EMBL:AAM70421.1}; GN Name=ctxB {ECO:0000313|EMBL:AAM70421.1}; OS Vibrio virus CTXphi. OG Plasmid pCTX-2 {ECO:0000313|EMBL:AGZ02057.1}. OC Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes; OC Tubulavirales; Inoviridae; Affertcholeramvirus. OX NCBI_TaxID=141904 {ECO:0000313|EMBL:AAM70421.1}; RN [1] {ECO:0000313|EMBL:AAM74174.1} RP NUCLEOTIDE SEQUENCE. RA Rui Y., Kan B., Gao S.; RT "CtxAB gene of strains of Vibrio cholerae isolated from China."; RL Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:AAM70421.1} RP NUCLEOTIDE SEQUENCE. RA Rui Y., Kan B., Gao S., Liu Y., Qi G., Yu S.; RT "CTXphi and nct-CTXphi of Vibrio cholerae strains isolated from China."; RL Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|EMBL:BAG06739.1} RP NUCLEOTIDE SEQUENCE. RA Ehara M., Nguyen M.B., Nguyen T.D., Ngo C.T., Le H.T., Nguyen T.H., RA Iwami M.; RT "Epidemic strains of Vibrio cholerae O1, biotype El Tor with CTX prophage RT integrated into both chromosomes."; RL Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases. RN [4] {ECO:0000313|EMBL:BAG66066.1} RP NUCLEOTIDE SEQUENCE. RA Ehara M., Nguyen M.B., Nguyen T.D., Ngo C.T., Le H.T., Nguyen T.H., RA Tran H.H., Iwami M.; RT "Phage CTXphi encoding classical ctxB in an El Tor strain isolated in RT Vietnam in 2007."; RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases. RN [5] {ECO:0000313|EMBL:ACM16040.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=07.95vp {ECO:0000313|EMBL:ACM16040.1}, E1781 RC {ECO:0000313|EMBL:ACM16056.1}, and MG116926 RC {ECO:0000313|EMBL:ACM16046.1}; RA Lee J.H., Kim D.W.; RT "Variety of CTX prophage in Vibrio cholerae O1 El Tor strains that produce RT classical CTXB."; RL Submitted (NOV-2008) to the EMBL/GenBank/DDBJ databases. RN [6] {ECO:0000313|EMBL:ACV73685.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=01.07vp {ECO:0000313|EMBL:ACV91607.1}, 07.95vp RC {ECO:0000313|EMBL:ACV91542.1}, 12.02vp {ECO:0000313|EMBL:ACV91524.1}, RC B33 {ECO:0000313|EMBL:ACV91470.1}, E1781 RC {ECO:0000313|EMBL:ACV91560.1}, IB4322 {ECO:0000313|EMBL:ACV91581.1}, RC IB4642 {ECO:0000313|EMBL:ACV91594.1}, MG116926 RC {ECO:0000313|EMBL:ACV91506.1}, and MJ1236 RC {ECO:0000313|EMBL:ACV91488.1}; RX PubMed=20127474; DOI=10.1007/s12275-009-0292-6; RA Lee J.H., Choi S.Y., Jeon Y.S., Lee H.R., Kim E.J., Nguyen B.M., Hien N.T., RA Ansaruzzaman M., Islam M.S., Bhuiyan N.A., Niyogi S.K., Sarkar B.L., RA Nair G.B., Kim D.S., Lopez A.L., Czerkinsky C., Clemens J.D., Chun J., RA Kim D.W.; RT "Classification of hybrid and altered Vibrio cholerae strains by CTX RT prophage and RS1 element structure."; RL J. Microbiol. 47:783-788(2009). RN [7] {ECO:0000313|EMBL:ACV73685.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=01.07vp {ECO:0000313|EMBL:ACV91607.1}, 07.95vp RC {ECO:0000313|EMBL:ACV91542.1}, 12.02vp {ECO:0000313|EMBL:ACV91524.1}, RC B33 {ECO:0000313|EMBL:ACV91470.1}, E1781 RC {ECO:0000313|EMBL:ACV91560.1}, IB4322 {ECO:0000313|EMBL:ACV91581.1}, RC IB4642 {ECO:0000313|EMBL:ACV91594.1}, MG116926 RC {ECO:0000313|EMBL:ACV91506.1}, and MJ1236 RC {ECO:0000313|EMBL:ACV91488.1}; RA Lee J.H., Kim D.W.; RT "Diversity of Vibrio cholerae O1 biotype El Tor strains producing classical RT type cholera toxin B."; RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases. RN [8] {ECO:0000313|EMBL:ACT83406.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=20621579; DOI=10.1016/j.meegid.2010.05.015; RA Mantri C.K., Mohapatra S.S., Singh D.V.; RT "Effect of storage and sodium chloride on excision of CTXPhi or pre-CTXPhi RT and CTXPhi from Vibrio cholerae O139 strains."; RL Infect. Genet. Evol. 10:925-930(2010). RN [9] {ECO:0000313|EMBL:ACV95543.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=IB1346 {ECO:0000313|EMBL:ACV95543.1}, IB1482 RC {ECO:0000313|EMBL:ACV95601.1}, IB1617 {ECO:0000313|EMBL:ACV95591.1}, RC and IB1627 {ECO:0000313|EMBL:ACV95578.1}; RX PubMed=20007761; DOI=10.1099/jmm.0.017053-0; RA Choi S.Y., Lee J.H., Kim E.J., Lee H.R., Jeon Y.S., von Seidlein L., RA Deen J., Ansaruzzaman M., Lucas G.M., Barreto A., Songane F.F., RA Mondlane C., Nair G.B., Czerkinsky C., Clemens J.D., Chun J., Kim D.W.; RT "Classical RS1 and environmental RS1 elements in Vibrio cholerae O1 El Tor RT strains harbouring a tandem repeat of CTX prophage: revisiting Mozambique RT in 2005."; RL J. Med. Microbiol. 59:302-308(2010). RN [10] {ECO:0000313|EMBL:ADX31889.1, ECO:0000313|Proteomes:UP000202246} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Lee J.H., Kim D.W.; RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases. RN [11] {ECO:0000313|EMBL:AEK94076.1} RP NUCLEOTIDE SEQUENCE. RA Mohapatra S.S., Mantri C.K., Fazil M.H.U.T., Singh D.V.; RT "Vibrio cholerae O1 biotype El Tor strains isolated in 1992 from Varanasi, RT India harboured El Tor CTXphi and classical ctxB on the chromosome-I and RT classical CTXphi and classical ctxB on the chromosome-II."; RL Environ. Microbiol. Rep. 3:783-790(2011). RN [12] {ECO:0000313|EMBL:AEB78280.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=VC104 {ECO:0000313|EMBL:AEB78280.1}, VC105 RC {ECO:0000313|EMBL:AEB78281.1}, VC106 {ECO:0000313|EMBL:AEB78282.1}, RC VC107 {ECO:0000313|EMBL:AEB78283.1}, VC108 RC {ECO:0000313|EMBL:AEB78284.1}, VC110 {ECO:0000313|EMBL:AEB78285.1}, RC VC111 {ECO:0000313|EMBL:AEB78286.1}, VC114 RC {ECO:0000313|EMBL:AEB78287.1}, VC115 {ECO:0000313|EMBL:AEB78288.1}, RC VC118 {ECO:0000313|EMBL:AEB78289.1}, VC119 RC {ECO:0000313|EMBL:AEB78290.1}, and VC120 RC {ECO:0000313|EMBL:AEB78291.1}; RA Mohapatra S.S., Mantri C.K., Fazil M.H.U.T.T., Singh D.V.; RT "Vibrio cholerae O1 biotype El Tor strains isolated in 1992 from Varanasi, RT India harboured El Tor CTXphi and classical ctxB on the chromosome-I and RT classical CTXphi and classical ctxB on the chromosome-II."; RL Environ. Microbiol. Rep. 3:783-790(2011). RN [13] {ECO:0000313|EMBL:AGZ02057.1} RP NUCLEOTIDE SEQUENCE. RC PLASMID=pCTX-2 {ECO:0000313|EMBL:AGZ02057.1}; RX PubMed=25233006; RA Kim E.J., Lee D., Moon S.H., Lee C.H., Kim S.J., Lee J.H., Kim J.O., RA Song M., Das B., Clemens J.D., Pape J.W., Nair G.B., Kim D.W.; RT "Molecular Insights Into the Evolutionary Pathway of Vibrio cholerae O1 RT Atypical El Tor Variants."; RL PLoS Pathog. 10:E1004384-E1004384(2014). RN [14] {ECO:0000313|EMBL:AHY24962.1, ECO:0000313|Proteomes:UP000024440} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Kim E.J., Kim D.W.; RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases. RN [15] {ECO:0000313|EMBL:AIZ03621.1, ECO:0000313|Proteomes:UP000277310} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=81 {ECO:0000313|EMBL:AIZ03621.1, RC ECO:0000313|Proteomes:UP000277310}; RA Pisanov R.R.V., Monakhova E.E.V., Kermanov A.A.V.; RT "Annual monitoring of river water."; RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases. RN [16] {ECO:0000313|EMBL:AWD92952.1, ECO:0000313|Proteomes:UP000247177} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Monakhova E.V., Pisanov R.V., Ezhova M.I., Titova S.V.; RT "Genotypic characterization of toxigenic Vibrio cholerae strains isolated RT in Russia."; RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF510994; AAM70421.1; -; Genomic_DNA. DR EMBL; AF510995; AAM70424.1; -; Genomic_DNA. DR EMBL; AF516342; AAM74174.1; -; Genomic_DNA. DR EMBL; AF516343; AAM74177.1; -; Genomic_DNA. DR EMBL; AF516347; AAM74189.1; -; Genomic_DNA. DR EMBL; FJ449739; ACM16040.1; -; Genomic_DNA. DR EMBL; FJ449741; ACM16042.1; -; Genomic_DNA. DR EMBL; FJ449742; ACM16044.1; -; Genomic_DNA. DR EMBL; FJ449744; ACM16046.1; -; Genomic_DNA. DR EMBL; FJ449745; ACM16048.1; -; Genomic_DNA. DR EMBL; FJ449749; ACM16056.1; -; Genomic_DNA. DR EMBL; FJ449750; ACM16058.1; -; Genomic_DNA. DR EMBL; GQ214706; ACT83406.1; -; Genomic_DNA. DR EMBL; GQ214707; ACT83407.1; -; Genomic_DNA. DR EMBL; GQ214708; ACT83408.1; -; Genomic_DNA. DR EMBL; GQ214709; ACT83409.1; -; Genomic_DNA. DR EMBL; GQ214710; ACT83410.1; -; Genomic_DNA. DR EMBL; GQ499847; ACV73685.1; -; Genomic_DNA. DR EMBL; GQ485644; ACV91470.1; -; Genomic_DNA. DR EMBL; GQ485644; ACV91478.1; -; Genomic_DNA. DR EMBL; GQ485645; ACV91488.1; -; Genomic_DNA. DR EMBL; GQ485645; ACV91497.1; -; Genomic_DNA. DR EMBL; GQ485646; ACV91506.1; -; Genomic_DNA. DR EMBL; GQ485646; ACV91515.1; -; Genomic_DNA. DR EMBL; GQ485647; ACV91524.1; -; Genomic_DNA. DR EMBL; GQ485647; ACV91533.1; -; Genomic_DNA. DR EMBL; GQ485648; ACV91542.1; -; Genomic_DNA. DR EMBL; GQ485648; ACV91551.1; -; Genomic_DNA. DR EMBL; GQ485649; ACV91560.1; -; Genomic_DNA. DR EMBL; GQ485649; ACV91569.1; -; Genomic_DNA. DR EMBL; GQ485650; ACV91581.1; -; Genomic_DNA. DR EMBL; GQ485651; ACV91594.1; -; Genomic_DNA. DR EMBL; GQ485652; ACV91607.1; -; Genomic_DNA. DR EMBL; GQ466608; ACV95543.1; -; Genomic_DNA. DR EMBL; GQ466609; ACV95560.1; -; Genomic_DNA. DR EMBL; GQ466609; ACV95569.1; -; Genomic_DNA. DR EMBL; GQ466610; ACV95578.1; -; Genomic_DNA. DR EMBL; GQ466611; ACV95591.1; -; Genomic_DNA. DR EMBL; GQ466612; ACV95601.1; -; Genomic_DNA. DR EMBL; GQ466612; ACV95610.1; -; Genomic_DNA. DR EMBL; HQ224500; ADX31889.1; -; Genomic_DNA. DR EMBL; HQ404503; AEB78280.1; -; Genomic_DNA. DR EMBL; HQ404504; AEB78281.1; -; Genomic_DNA. DR EMBL; HQ404505; AEB78282.1; -; Genomic_DNA. DR EMBL; HQ404506; AEB78283.1; -; Genomic_DNA. DR EMBL; HQ404507; AEB78284.1; -; Genomic_DNA. DR EMBL; HQ404508; AEB78285.1; -; Genomic_DNA. DR EMBL; HQ404509; AEB78286.1; -; Genomic_DNA. DR EMBL; HQ404510; AEB78287.1; -; Genomic_DNA. DR EMBL; HQ404511; AEB78288.1; -; Genomic_DNA. DR EMBL; HQ404512; AEB78289.1; -; Genomic_DNA. DR EMBL; HQ404513; AEB78290.1; -; Genomic_DNA. DR EMBL; HQ404514; AEB78291.1; -; Genomic_DNA. DR EMBL; GQ144654; AEK94076.1; -; Genomic_DNA. DR EMBL; GQ144655; AEK94077.1; -; Genomic_DNA. DR EMBL; GQ144656; AEK94078.1; -; Genomic_DNA. DR EMBL; GQ144657; AEK94079.1; -; Genomic_DNA. DR EMBL; KF664567; AGZ02057.1; -; Genomic_DNA. DR EMBL; KF664567; AGZ02066.1; -; Genomic_DNA. DR EMBL; KF664572; AGZ02096.1; -; Genomic_DNA. DR EMBL; KJ619459; AHY24962.1; -; Genomic_DNA. DR EMBL; KM352500; AIZ03621.1; -; Genomic_DNA. DR EMBL; MF155889; AWD92952.1; -; Genomic_DNA. DR EMBL; AB378082; BAG06739.1; -; Genomic_DNA. DR EMBL; AB449339; BAG66066.1; -; Genomic_DNA. DR RefSeq; YP_004286241.1; NC_015209.1. DR SMR; Q8LT24; -. DR GeneID; 10271078; -. DR KEGG; vg:10271078; -. DR KO; K10929; -. DR Proteomes; UP000024440; Genome. DR Proteomes; UP000202246; Genome. DR Proteomes; UP000247177; Genome. DR Proteomes; UP000277310; Genome. DR GO; GO:0005576; C:extracellular region; IEA:InterPro. DR GO; GO:0098676; P:modulation of host virulence by virus; IEA:UniProtKB-KW. DR GO; GO:0009405; P:pathogenesis; IEA:InterPro. DR InterPro; IPR008992; Enterotoxin. DR InterPro; IPR001835; Enterotoxin_B. DR Pfam; PF01376; Enterotoxin_b; 1. DR PRINTS; PR00772; ENTEROTOXINB. DR SUPFAM; SSF50203; SSF50203; 1. PE 4: Predicted; KW Modulation of host virulence by virus {ECO:0000256|ARBA:ARBA00023092}; KW Plasmid {ECO:0000313|EMBL:AGZ02057.1}; KW Reference proteome {ECO:0000313|Proteomes:UP000024440}; KW Toxin {ECO:0000256|ARBA:ARBA00022509}; KW Viral exotoxin {ECO:0000256|ARBA:ARBA00022509}; KW Virulence {ECO:0000256|ARBA:ARBA00023092}. SQ SEQUENCE 124 AA; 13919 MW; D6BF83FFF7924EA3 CRC64; MIKLKFGVFF TVLLSSAYAH GTPQNITDLC AEYHNTQIHT LNDKIFSYTE SLAGKREMAI ITFKNGATFQ VEVPGSQHID SQKKAIERMK DTLRIAYLTE AKVEKLCVWN NKTPHAIAAI SMAN //