ID PHR2_ARATH Reviewed; 447 AA. AC Q8LB72; O22253; DT 17-OCT-2006, integrated into UniProtKB/Swiss-Prot. DT 17-OCT-2006, sequence version 2. DT 22-FEB-2023, entry version 108. DE RecName: Full=Blue-light photoreceptor PHR2; GN Name=PHR2; OrderedLocusNames=At2g47590; ORFNames=T30B22.11; OS Arabidopsis thaliana (Mouse-ear cress). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis. OX NCBI_TaxID=3702; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA]. RC STRAIN=cv. Columbia; RA Ahmad M., Jarillo J.A., Cashmore A.R.; RT "PHR2: a novel Arabidopsis gene related to the blue-light RT photoreceptor/photolyase family."; RL (er) Plant Gene Register PGR98-096(1998). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Columbia; RX PubMed=10617197; DOI=10.1038/45471; RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.; RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana."; RL Nature 402:761-768(1999). RN [3] RP GENOME REANNOTATION. RC STRAIN=cv. Columbia; RX PubMed=27862469; DOI=10.1111/tpj.13415; RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S., RA Town C.D.; RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference RT genome."; RL Plant J. 89:789-804(2017). RN [4] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., RA Feldmann K.A.; RT "Full-length cDNA from Arabidopsis thaliana."; RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases. CC -!- COFACTOR: CC Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000250}; CC Note=Binds 1 FAD per subunit. {ECO:0000250}; CC -!- SIMILARITY: Belongs to the DNA photolyase class-1 family. CC {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF053366; AAC26199.1; -; mRNA. DR EMBL; AC002535; AAC62851.1; -; Genomic_DNA. DR EMBL; CP002685; AEC10862.1; -; Genomic_DNA. DR EMBL; AY087383; AAM64933.1; -; mRNA. DR PIR; T00425; T00425. DR RefSeq; NP_182281.1; NM_130327.4. DR AlphaFoldDB; Q8LB72; -. DR SMR; Q8LB72; -. DR BioGRID; 4707; 4. DR STRING; 3702.AT2G47590.1; -. DR PaxDb; Q8LB72; -. DR ProteomicsDB; 235106; -. DR EnsemblPlants; AT2G47590.1; AT2G47590.1; AT2G47590. DR GeneID; 819372; -. DR Gramene; AT2G47590.1; AT2G47590.1; AT2G47590. DR KEGG; ath:AT2G47590; -. DR Araport; AT2G47590; -. DR TAIR; locus:2061961; AT2G47590. DR eggNOG; KOG0133; Eukaryota. DR HOGENOM; CLU_010348_0_0_1; -. DR InParanoid; Q8LB72; -. DR OMA; VMKDEGL; -. DR OrthoDB; 124765at2759; -. DR PhylomeDB; Q8LB72; -. DR PRO; PR:Q8LB72; -. DR Proteomes; UP000006548; Chromosome 2. DR ExpressionAtlas; Q8LB72; baseline and differential. DR Genevisible; Q8LB72; AT. DR GO; GO:0003904; F:deoxyribodipyrimidine photo-lyase activity; IBA:GO_Central. DR GO; GO:0003677; F:DNA binding; IBA:GO_Central. DR GO; GO:0071949; F:FAD binding; IBA:GO_Central. DR GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW. DR GO; GO:0000719; P:photoreactive repair; IBA:GO_Central. DR Gene3D; 1.25.40.80; -; 1. DR Gene3D; 3.40.50.620; HUPs; 1. DR InterPro; IPR036134; Crypto/Photolyase_FAD-like_sf. DR InterPro; IPR036155; Crypto/Photolyase_N_sf. DR InterPro; IPR002081; Cryptochrome/DNA_photolyase_1. DR InterPro; IPR006050; DNA_photolyase_N. DR InterPro; IPR014729; Rossmann-like_a/b/a_fold. DR PANTHER; PTHR11455:SF2; BLUE-LIGHT PHOTORECEPTOR PHR2; 1. DR PANTHER; PTHR11455; CRYPTOCHROME; 1. DR Pfam; PF00875; DNA_photolyase; 1. DR SUPFAM; SSF48173; Cryptochrome/photolyase FAD-binding domain; 1. DR SUPFAM; SSF52425; Cryptochrome/photolyase, N-terminal domain; 1. DR PROSITE; PS51645; PHR_CRY_ALPHA_BETA; 1. PE 2: Evidence at transcript level; KW Chromophore; FAD; Flavoprotein; Photoreceptor protein; Receptor; KW Reference proteome; Sensory transduction. FT CHAIN 1..447 FT /note="Blue-light photoreceptor PHR2" FT /id="PRO_0000253763" FT DOMAIN 115..249 FT /note="Photolyase/cryptochrome alpha/beta" FT REGION 1..20 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 447 AA; 48878 MW; 29194B6DBDF6DA7C CRC64; MDSSNVEENL NPETKSAEEQ NPLAIFHSSL PIASLSLTLF PSSTQFLKLF AHHPNKVKIP TQASSLTHLS LSSVSPFPSS RISFKSTIAA NPLQSPLSIV PRRPVDPSSA AALRRAAVVW FRNDLRVHDN ECLNSANDEC VSVLPVYCFD PRDYGKSSSG FDKTGPFRAQ FLIESVSELR KNLQARGSNL VVRVGKPEAV LVELAKEIGA DAVYAHREVS HDEVKAEGKI ETAMKEEGVE VKYFWGSTLY HLDDLPFKIE DLPSNYGAFK DKVQKLEIRK TIAALDQLKS LPSRGDVELG DIPSLLDLGI SPTPRTSQEG KPTMVGGETE ALTRLKSFAA DCQARLSKGN QKGGNNSVFG ANFSCKISPW LAMGSISPRS MFDELKKTIS ASTTSTTPRN GPGDTGLNWL MYELLWRDFF RFITKKYSSA KTQVEAGPAT ACTGAFA //