ID Q8IZE1_HUMAN Unreviewed; 44 AA. AC Q8IZE1; DT 01-MAR-2003, integrated into UniProtKB/TrEMBL. DT 01-MAR-2003, sequence version 1. DT 31-OCT-2012, entry version 46. DE SubName: Full=Truncated tyrosine hydroxylase; DE Flags: Fragment; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Neuroblastoma; RX MEDLINE=22381858; PubMed=12493595; DOI=10.1016/S0304-3940(02)01220-X; RA Parareda A., Villaescusa J.C., Sanchez de Toledo J., Gallego S.; RT "New splicing variants for human Tyrosine Hydroxylase gene with RT possible implications for the detection of minimal residual disease in RT patients with neuroblastoma."; RL Neurosci. Lett. 336:29-32(2003). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY144495; AAN39539.1; -; mRNA. DR IPI; IPI00878515; -. DR UniGene; Hs.435609; -. DR HSSP; P04177; 1TOH. DR ProteinModelPortal; Q8IZE1; -. DR STRING; Q8IZE1; -. DR ArrayExpress; Q8IZE1; -. DR Bgee; Q8IZE1; -. DR GO; GO:0030659; C:cytoplasmic vesicle membrane; IEA:Compara. DR GO; GO:0005829; C:cytosol; IEA:Compara. DR GO; GO:0030425; C:dendrite; IEA:Compara. DR GO; GO:0005739; C:mitochondrion; IEA:Compara. DR GO; GO:0005634; C:nucleus; IEA:Compara. DR GO; GO:0043204; C:perikaryon; IEA:Compara. DR GO; GO:0008021; C:synaptic vesicle; IEA:Compara. DR GO; GO:0043195; C:terminal button; IEA:Compara. DR GO; GO:0016597; F:amino acid binding; IEA:Compara. DR GO; GO:0035240; F:dopamine binding; IEA:Compara. DR GO; GO:0008199; F:ferric iron binding; IEA:Compara. DR GO; GO:0008198; F:ferrous iron binding; IEA:Compara. DR GO; GO:0019825; F:oxygen binding; IEA:Compara. DR GO; GO:0034617; F:tetrahydrobiopterin binding; IEA:Compara. DR GO; GO:0004511; F:tyrosine 3-monooxygenase activity; IEA:Compara. DR GO; GO:0035690; P:cellular response to drug; IEA:Compara. DR GO; GO:0071333; P:cellular response to glucose stimulus; IEA:Compara. DR GO; GO:0071363; P:cellular response to growth factor stimulus; IEA:Compara. DR GO; GO:0071287; P:cellular response to manganese ion; IEA:Compara. DR GO; GO:0071316; P:cellular response to nicotine; IEA:Compara. DR GO; GO:0021987; P:cerebral cortex development; IEA:Compara. DR GO; GO:0042745; P:circadian sleep/wake cycle; IEA:Compara. DR GO; GO:0006585; P:dopamine biosynthetic process from tyrosine; IEA:Compara. DR GO; GO:0042755; P:eating behavior; IEA:Compara. DR GO; GO:0048596; P:embryonic camera-type eye morphogenesis; IEA:Compara. DR GO; GO:0042462; P:eye photoreceptor cell development; IEA:Compara. DR GO; GO:0006631; P:fatty acid metabolic process; IEA:Compara. DR GO; GO:0007507; P:heart development; IEA:Compara. DR GO; GO:0033076; P:isoquinoline alkaloid metabolic process; IEA:Compara. DR GO; GO:0007612; P:learning; IEA:Compara. DR GO; GO:0007626; P:locomotory behavior; IEA:Compara. DR GO; GO:0007617; P:mating behavior; IEA:Compara. DR GO; GO:0007613; P:memory; IEA:Compara. DR GO; GO:0010259; P:multicellular organismal aging; IEA:Compara. DR GO; GO:0018963; P:phthalate metabolic process; IEA:Compara. DR GO; GO:0052314; P:phytoalexin metabolic process; IEA:Compara. DR GO; GO:0008016; P:regulation of heart contraction; IEA:Compara. DR GO; GO:0014823; P:response to activity; IEA:Compara. DR GO; GO:0001975; P:response to amphetamine; IEA:Compara. DR GO; GO:0051412; P:response to corticosterone stimulus; IEA:Compara. DR GO; GO:0051602; P:response to electrical stimulus; IEA:Compara. DR GO; GO:0032355; P:response to estradiol stimulus; IEA:Compara. DR GO; GO:0045471; P:response to ethanol; IEA:Compara. DR GO; GO:0045472; P:response to ether; IEA:Compara. DR GO; GO:0009635; P:response to herbicide; IEA:Compara. DR GO; GO:0001666; P:response to hypoxia; IEA:Compara. DR GO; GO:0009416; P:response to light stimulus; IEA:Compara. DR GO; GO:0032496; P:response to lipopolysaccharide; IEA:Compara. DR GO; GO:0031667; P:response to nutrient levels; IEA:Compara. DR GO; GO:0043434; P:response to peptide hormone stimulus; IEA:Compara. DR GO; GO:0046684; P:response to pyrethroid; IEA:Compara. DR GO; GO:0009651; P:response to salt stress; IEA:Compara. DR GO; GO:0009414; P:response to water deprivation; IEA:Compara. DR GO; GO:0010043; P:response to zinc ion; IEA:Compara. DR GO; GO:0007605; P:sensory perception of sound; IEA:Compara. DR GO; GO:0035176; P:social behavior; IEA:Compara. DR GO; GO:0006665; P:sphingolipid metabolic process; IEA:Compara. DR GO; GO:0001963; P:synaptic transmission, dopaminergic; IEA:Compara. DR GO; GO:0015842; P:synaptic vesicle amine transport; IEA:Compara. DR GO; GO:0042214; P:terpene metabolic process; IEA:Compara. DR GO; GO:0007601; P:visual perception; IEA:Compara. DR Gene3D; G3DSA:1.10.800.10; Aaa_hydroxylase; 1. DR InterPro; IPR001273; ArAA_hydroxylase. DR InterPro; IPR019774; Aromatic-AA_hydroxylase_C. DR PANTHER; PTHR11473; PTHR11473; 1. DR Pfam; PF00351; Biopterin_H; 1. DR SUPFAM; SSF56534; Aaa_hydroxylase; 1. DR PROSITE; PS51410; BH4_AAA_HYDROXYL_2; 1. PE 2: Evidence at transcript level; FT NON_TER 1 1 SQ SEQUENCE 44 AA; 5203 MW; 6E4BCB99D0827690 CRC64; DLDHPGFSDQ VYRQRRKLIA EIAFQYRHGD PIPRVEYTAE EIAT //