ID Q8IP90_DROME Unreviewed; 810 AA. AC Q8IP90; DT 01-MAR-2003, integrated into UniProtKB/TrEMBL. DT 01-MAR-2003, sequence version 1. DT 14-OCT-2015, entry version 123. DE SubName: Full=Arrest, isoform G {ECO:0000313|EMBL:AGB92938.1}; DE SubName: Full=CG31762-PB, isoform B {ECO:0000313|EMBL:AAN10810.1}; DE SubName: Full=FI19388p1 {ECO:0000313|EMBL:AFA28453.1}; GN Name=aret {ECO:0000313|EMBL:AAN10810.1, GN ECO:0000313|FlyBase:FBgn0000114}; GN Synonyms=aret-RB {ECO:0000313|EMBL:AFA28453.1}; GN ORFNames=CG31762 {ECO:0000313|FlyBase:FBgn0000114}, Dmel_CG31762 GN {ECO:0000313|EMBL:AAN10810.1}; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227 {ECO:0000313|EMBL:AAN10810.1, ECO:0000313|Proteomes:UP000000803}; RN [1] {ECO:0000313|EMBL:AAN10810.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., RA Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., RA Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., RA Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [2] {ECO:0000313|EMBL:AAN10810.1} RP NUCLEOTIDE SEQUENCE. RG Berkeley Drosophila Genome Project; RA Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R., RA Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E., RA Yu C., Rubin G.; RT "Drosophila melanogaster release 4 sequence."; RL Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases. RN [3] {ECO:0000313|EMBL:AAN10810.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537568; RA Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., RA Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., RA George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., RA Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J., RA Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., RA Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.; RT "Finishing a whole-genome shotgun: release 3 of the Drosophila RT melanogaster euchromatic genome sequence."; RL Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002). RN [4] {ECO:0000313|EMBL:AAN10810.1, ECO:0000313|Proteomes:UP000000803} RP GENOME REANNOTATION. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). RN [5] {ECO:0000313|EMBL:AAN10810.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537573; RA Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., RA Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., RA Ashburner M., Celniker S.E.; RT "The transposable elements of the Drosophila melanogaster euchromatin: RT a genomics perspective."; RL Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002). RN [6] {ECO:0000313|EMBL:AGB92938.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537574; RA Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., RA Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., RA Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., RA Karpen G.H.; RT "Heterochromatic sequences in a Drosophila whole-genome shotgun RT assembly."; RL Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002). RN [7] {ECO:0000313|EMBL:AGB92938.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=16110336; DOI=10.1371/journal.pcbi.0010022; RA Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., RA Ashburner M., Anxolabehere D.; RT "Combined evidence annotation of transposable elements in genome RT sequences."; RL PLoS Comput. Biol. 1:166-175(2005). RN [8] {ECO:0000313|EMBL:AAN10810.1} RP NUCLEOTIDE SEQUENCE. RG FlyBase; RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases. RN [9] {ECO:0000313|EMBL:AGB92938.1} RP NUCLEOTIDE SEQUENCE. RA Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S., RA Svirskas R., Rubin G.; RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. RN [10] {ECO:0000313|EMBL:AGB92938.1} RP NUCLEOTIDE SEQUENCE. RG Berkeley Drosophila Genome Project; RA Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R., RA Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E., RA Yu C., Rubin G.; RT "Drosophila melanogaster release 4 sequence."; RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases. RN [11] {ECO:0000313|EMBL:AGB92938.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569856; DOI=10.1126/science.1139815; RA Smith C.D., Shu S., Mungall C.J., Karpen G.H.; RT "The Release 5.1 annotation of Drosophila melanogaster RT heterochromatin."; RL Science 316:1586-1591(2007). RN [12] {ECO:0000313|EMBL:AGB92938.1, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569867; DOI=10.1126/science.1139816; RA Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M., RA Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A., RA Dimitri P., Karpen G.H., Celniker S.E.; RT "Sequence finishing and mapping of Drosophila melanogaster RT heterochromatin."; RL Science 316:1625-1628(2007). RN [13] {ECO:0000313|EMBL:AFA28453.1} RP NUCLEOTIDE SEQUENCE. RA Carlson J., Booth B., Frise E., Park S., Wan K., Yu C., Celniker S.; RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases. RN [14] {ECO:0000313|EMBL:AGB92938.1} RP NUCLEOTIDE SEQUENCE. RG FlyBase; RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE003635; AAN10810.1; -; Genomic_DNA. DR EMBL; BT133212; AFA28453.1; -; mRNA. DR EMBL; AE014134; AGB92938.1; -; Genomic_DNA. DR RefSeq; NP_001260403.1; NM_001273474.1. DR RefSeq; NP_723737.1; NM_165002.2. DR UniGene; Dm.4487; -. DR MINT; MINT-1597685; -. DR STRING; 7227.FBpp0079926; -. DR GeneID; 34648; -. DR UCSC; CG31762-RB; d. melanogaster. DR CTD; 34648; -. DR FlyBase; FBgn0000114; aret. DR OMA; ASAYMST; -. DR GenomeRNAi; 34648; -. DR NextBio; 789496; -. DR Proteomes; UP000000803; Chromosome 2L. DR GO; GO:0005737; C:cytoplasm; IDA:FlyBase. DR GO; GO:0016604; C:nuclear body; IDA:FlyBase. DR GO; GO:0031965; C:nuclear membrane; IDA:FlyBase. DR GO; GO:0005634; C:nucleus; IDA:FlyBase. DR GO; GO:0043186; C:P granule; IDA:FlyBase. DR GO; GO:0003730; F:mRNA 3'-UTR binding; IDA:FlyBase. DR GO; GO:0003729; F:mRNA binding; ISS:FlyBase. DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro. DR GO; GO:0003723; F:RNA binding; IDA:FlyBase. DR GO; GO:0036099; P:female germ-line stem cell maintenance; IGI:FlyBase. DR GO; GO:0007281; P:germ cell development; IMP:FlyBase. DR GO; GO:0042078; P:germ-line stem cell division; NAS:FlyBase. DR GO; GO:0030727; P:germarium-derived female germ-line cyst formation; TAS:FlyBase. DR GO; GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase. DR GO; GO:0002121; P:inter-male aggressive behavior; IMP:FlyBase. DR GO; GO:0006378; P:mRNA polyadenylation; TAS:FlyBase. DR GO; GO:0007319; P:negative regulation of oskar mRNA translation; IDA:FlyBase. DR GO; GO:0017148; P:negative regulation of translation; IMP:FlyBase. DR GO; GO:0048477; P:oogenesis; IMP:FlyBase. DR GO; GO:0031536; P:positive regulation of exit from mitosis; IMP:FlyBase. DR GO; GO:2000738; P:positive regulation of stem cell differentiation; IMP:FlyBase. DR GO; GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IMP:FlyBase. DR GO; GO:0014881; P:regulation of myofibril size; IMP:FlyBase. DR GO; GO:0046011; P:regulation of oskar mRNA translation; TAS:FlyBase. DR GO; GO:0045214; P:sarcomere organization; IMP:FlyBase. DR GO; GO:0007286; P:spermatid development; IMP:FlyBase. DR Gene3D; 3.30.70.330; -; 3. DR InterPro; IPR012677; Nucleotide-bd_a/b_plait. DR InterPro; IPR000504; RRM_dom. DR Pfam; PF00076; RRM_1; 3. DR SMART; SM00360; RRM; 3. DR PROSITE; PS50102; RRM; 3. PE 2: Evidence at transcript level; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Complete proteome {ECO:0000313|Proteomes:UP000000803}; KW Reference proteome {ECO:0000313|Proteomes:UP000000803}. FT COILED 178 212 {ECO:0000256|SAM:Coils}. FT COILED 520 547 {ECO:0000256|SAM:Coils}. SQ SEQUENCE 810 AA; 88271 MW; F6669D8A1449D40B CRC64; MLSSLDALAG KIATATPGTG AVTADSKNTQ SLHHHHRLDY DYSAVEIEPP AEQLANSPRS ERERLQQAQQ AYEQQAQAEL EFGLAEVDAK LTQLKSSHSL QHHHSHHHQL QRHTALNQQQ QQLHHHQPHH NHHHHHPYQR PRPTSPPQQQ TSSYQQQLSQ LAALQDHHDL LQTQQELFHK QLATMQEYQR ERERERERER ERERERERER DRSSFIDNSD YDSQTEFKIC LRDSAFGMSD KSSSATNSLP NSPIHSNNNN PSLLNNNNNN SNGTSSNNSL NVGNNNSNPS LGGSNSNALV SVGSNGIMSA AGLVNNNNNP CSANRNVVAM VDDDACFRLD TDATVTYGEK EPDPDNIKMF VGQVPKSMDE SQLREMFEEY GAVHSINVLR DKATGISKGC CFVTFYTRHA ALKAQDALHN VKTLNGMYHP IQMKPADSEN RNERKLFVGM LNKKLNENDV RKLFEVHGAI EECTVLRDQN GQSKGCAFVT FATKHAAISA IKVTLSQNKI MEGCTSPLVV KFADTQKEKE QKKIQQIQAN LWNLASNINI PLGQTATSVT TPILPNPPQQ PSPVLGADAI TPASIQLLQQ LQAVGLQHQL LQALTGLGAQ QSSSATDTSA VAAAGLLTPM TVQNLAAIAA MTQPSLSNAA AAAAAATSPG SAQLTNTAAL LWSDPNPMAS AYMSTAAGLP QFGSASALST SPLASVALSA AAAAAAGKQI EGPEGCNLFI YHLPQEFTDT DLASTFLPFG NVISAKVFID KQTSLSKCFG FVSFDNPDSA QVAIKAMNGF QVGTKRLKVQ LKKPKDSKPY //