ID Q8IIT5_PLAF7 Unreviewed; 1501 AA. AC Q8IIT5; DT 01-MAR-2003, integrated into UniProtKB/TrEMBL. DT 22-SEP-2009, sequence version 2. DT 26-FEB-2020, entry version 115. DE SubName: Full=Pseudo-tyrosine kinase-like protein {ECO:0000313|EMBL:CZT98734.1}; GN ORFNames=PF3D7_1106800 {ECO:0000313|EMBL:CZT98734.1}; OS Plasmodium falciparum (isolate 3D7). OC Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; OC Plasmodiidae; Plasmodium; Plasmodium (Laverania). OX NCBI_TaxID=36329 {ECO:0000313|EMBL:CZT98734.1, ECO:0000313|Proteomes:UP000001450}; RN [1] {ECO:0000313|EMBL:CZT98734.1, ECO:0000313|Proteomes:UP000001450} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Isolate 3D7 {ECO:0000313|Proteomes:UP000001450}; RX PubMed=12368864; DOI=10.1038/nature01097; RA Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W., RA Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D., RA Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S., RA Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M., RA Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A., RA Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I., RA Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J., RA Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.; RT "Genome sequence of the human malaria parasite Plasmodium falciparum."; RL Nature 419:498-511(2002). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; LN999945; CZT98734.1; -; Genomic_DNA. DR RefSeq; XP_001347755.2; XM_001347719.2. DR SMR; Q8IIT5; -. DR PRIDE; Q8IIT5; -. DR EnsemblProtists; CZT98734; CZT98734; PF3D7_1106800. DR GeneDB; PF3D7_1106800.1:pep; -. DR GeneID; 810631; -. DR KEGG; pfa:PF3D7_1106800; -. DR EuPathDB; PlasmoDB:PF3D7_1106800; -. DR HOGENOM; CLU_248690_0_0_1; -. DR OMA; LFSYLHC; -. DR Proteomes; UP000001450; Chromosome 11. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro. DR Gene3D; 1.10.150.50; -; 1. DR InterPro; IPR011009; Kinase-like_dom_sf. DR InterPro; IPR000719; Prot_kinase_dom. DR InterPro; IPR001660; SAM. DR InterPro; IPR013761; SAM/pointed_sf. DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom. DR Pfam; PF07714; Pkinase_Tyr; 3. DR Pfam; PF07647; SAM_2; 1. DR SMART; SM00454; SAM; 1. DR SUPFAM; SSF47769; SSF47769; 1. DR SUPFAM; SSF56112; SSF56112; 1. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. DR PROSITE; PS50105; SAM_DOMAIN; 1. PE 4: Predicted; KW ATP-binding {ECO:0000256|SAAS:SAAS00752238}; KW Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:CZT98734.1}; KW Nucleotide-binding {ECO:0000256|SAAS:SAAS00753232}; KW Reference proteome {ECO:0000313|Proteomes:UP000001450}; KW Transferase {ECO:0000313|EMBL:CZT98734.1}. FT REGION 204..223 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 257..276 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 392..425 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 543..607 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT REGION 659..678 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COILED 983..1003 FT /evidence="ECO:0000256|SAM:Coils" FT COMPBIAS 204..221 FT /note="Basic" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 257..272 FT /note="Polyampholyte" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 398..425 FT /note="Basic" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 543..575 FT /note="Polar" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 662..677 FT /note="Polyampholyte" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 1501 AA; 176120 MW; E517CBE251A2999F CRC64; MGNTLDSNKP KNFVTYADYK YIGKLNNKNE HHGIGIILYN SGESFYGSFI NGKKEGKGIY IDKNLTRYIN TWVDNKVFGK VKVVPYNSNR VYYFYYKNYM IEKCIYFDNN INNKESHHKN NIYNNYDNNS YNNNSCDDEE KRKYPIGVTK FKEDLSNYIH STHIMKKNNK LFNKNDNEYN IFSSSLSYSS DSENINLLDI LKKKKNKKNK KNKKKKNKKT KNTQILSCTQ HKMYEHNMNE SNFTKKDNVN CEHTDKMNIS LHEKNDKKNE KKNEKKNKKK KLFKYFSNNI ENLIIENYQT WSLREVIQWL MLCNVPVKWL ISFYKNNITG DKLKYININT IRNELGIIAY GHAIKILQLI KNLQVMAYNK KFNNLIQIEE YKNYIRQKEN TNKNIKKGKN IKKEKKKKKE KNIKKEKKKK KKETKKFNNM DKKYIDLAIH KNVKNIQNDT FYNKHENIYN CKNQTNFIYQ NDSEIKKIMN KKKVSFEYDN NEEKKKKNII KFIKNNKSLQ NSNGEYYLIN HLSKGICSDS IFYKSSQSKS SSQLSSPLSS PLSSPSPSSS PSSSPSSSPS SSPSSSPSPS SSPSPSSSPS SSPSSSPSSP PSPLSYKDNF PISSSCSSLE RLPSYEKKLL SSSQSNIEHI KNLPLDVLSN NNSSANIKIK KSKSKYNNDK KEQKKLPLIL NKSSSEFSPS HSYTSKSYHY NIKPSLQSSS NNSSDSSYSI SSTCSSSSSY VSSLYSNRSN DILNFYRNKI IKYCNNIYMN TKLAYSYMNG FIIPHEDLIF IHPIENYYMD NTNEKNNINN PYTKEKIMNH NFSFNTKNNT SFIDINTNIF SSNKQQNINN FGKYKKMKSR MFKGKYMGKE VAIKILVGKI KNFKKLHQIL YNLYNLRHSN LVLIMGVSIH YPFVFIIYEY MKNKCLFSYL HCIKYKHVYI STFLQRYKTL LHITQQEKIK KTNNINNNNN INHNNINNNN INHNNINHNN INNNNINNNN INYNKDYNNK KKKEDEQHNI EHQDTFIDLP EKSNISSDDN NSTDISQIQK ENFHFLNKKI EENKNIIYDD HTSTLSDHSI HNINKSYDNV YKNKMNIFHY QHNVLCGAYD NNDNNINDND IYCNNIYDNN INDNHIYCNN INDNHIYCNN INDNHIYCNN IYDHHKNTSL NSKEQNTDHN IEQINECNKY ASETKYNIKK SNLKNNIISH KNFQKCNQIQ MNQPYTFPPY QKELSSYLKN EKIKRKRKVL FSYLKTHIHF NSQQINDQHN RLSVQKIMKI ITDVTLACTY LEKEKMSPIN LKPTNILLDE SLNAKISDFG ISKIENCLDM NIDYSYKISS NSVIKINKKE YEQKKAKKIK IVNKNNNDLL YLYDHNNNVY KYNTQYIDVT YNNSYPSIFY WTPPEILRGK KNKKFYSDIY AFGIILWEML SNDIPYNYPF ASHIMAVVGY ANEELSFNNI PVSIQSLIKA CVNRNKYKRP TFEHILKTIS TLYQKANTKV EDALISFMDG T //