ID Q8IIT5_PLAF7 Unreviewed; 1501 AA. AC Q8IIT5; DT 01-MAR-2003, integrated into UniProtKB/TrEMBL. DT 22-SEP-2009, sequence version 2. DT 20-DEC-2017, entry version 101. DE SubName: Full=Conserved Plasmodium protein {ECO:0000313|EMBL:AAN35668.2}; DE SubName: Full=Protein kinase, putative {ECO:0000313|EMBL:CZT98734.1}; GN ORFNames=PF11_0079 {ECO:0000313|EMBL:AAN35668.2}, PF3D7_1106800 GN {ECO:0000313|EMBL:CZT98734.1}; OS Plasmodium falciparum (isolate 3D7). OC Eukaryota; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; OC Plasmodiidae; Plasmodium; Plasmodium (Laverania). OX NCBI_TaxID=36329 {ECO:0000313|EMBL:AAN35668.2, ECO:0000313|Proteomes:UP000001450}; RN [1] {ECO:0000313|EMBL:AAN35668.2, ECO:0000313|Proteomes:UP000001450} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=3D7 {ECO:0000313|EMBL:AAN35668.2}, and Isolate 3D7 RC {ECO:0000313|Proteomes:UP000001450}; RX PubMed=12368864; DOI=10.1038/nature01097; RA Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W., RA Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K., RA Eisen J.A., Rutherford K., Salzberg S.L., Craig A., Kyes S., RA Chan M.S., Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., RA Pertea M., Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., RA Martin D.M., Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., RA McFadden G.I., Cummings L.M., Subramanian G.M., Mungall C., RA Venter J.C., Carucci D.J., Hoffman S.L., Newbold C., Davis R.W., RA Fraser C.M., Barrell B.; RT "Genome sequence of the human malaria parasite Plasmodium RT falciparum."; RL Nature 419:498-511(2002). RN [2] {ECO:0000313|EMBL:AAN35668.2} RP NUCLEOTIDE SEQUENCE. RC STRAIN=3D7 {ECO:0000313|EMBL:CZT98734.1}; RG P. falciparum Genome Sequencing Consortium; RA Aslett M., Brunk B., Gardner M., Berriman M.; RL Submitted (JUL-2009) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE014186; AAN35668.2; -; Genomic_DNA. DR EMBL; LN999945; CZT98734.1; -; Genomic_DNA. DR RefSeq; XP_001347755.2; XM_001347719.2. DR SMR; Q8IIT5; -. DR EnsemblProtists; CZT98734; CZT98734; PF3D7_1106800. DR GeneDB; PF3D7_1106800.1:pep; -. DR GeneID; 810631; -. DR KEGG; pfa:PF11_0079; -. DR EuPathDB; PlasmoDB:PF3D7_1106800; -. DR InParanoid; Q8IIT5; -. DR OMA; HIYCNNI; -. DR Proteomes; UP000001450; Chromosome 11. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW. DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro. DR InterPro; IPR011009; Kinase-like_dom_sf. DR InterPro; IPR000719; Prot_kinase_dom. DR InterPro; IPR001660; SAM. DR InterPro; IPR013761; SAM/pointed_sf. DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom. DR Pfam; PF07714; Pkinase_Tyr; 3. DR Pfam; PF07647; SAM_2; 1. DR SMART; SM00454; SAM; 1. DR SUPFAM; SSF47769; SSF47769; 1. DR SUPFAM; SSF56112; SSF56112; 3. DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1. DR PROSITE; PS50105; SAM_DOMAIN; 1. PE 4: Predicted; KW ATP-binding {ECO:0000256|SAAS:SAAS00442036}; KW Coiled coil {ECO:0000256|SAM:Coils}; KW Complete proteome {ECO:0000313|Proteomes:UP000001450}; KW Kinase {ECO:0000313|EMBL:CZT98734.1}; KW Nucleotide-binding {ECO:0000256|SAAS:SAAS00047817}; KW Reference proteome {ECO:0000313|Proteomes:UP000001450}; KW Transferase {ECO:0000313|EMBL:CZT98734.1}. FT DOMAIN 301 366 SAM. {ECO:0000259|PROSITE:PS50105}. FT DOMAIN 1088 1483 Protein kinase. {ECO:0000259|PROSITE: FT PS50011}. FT COILED 198 221 {ECO:0000256|SAM:Coils}. FT COILED 261 281 {ECO:0000256|SAM:Coils}. FT COILED 399 433 {ECO:0000256|SAM:Coils}. FT COILED 983 1003 {ECO:0000256|SAM:Coils}. SQ SEQUENCE 1501 AA; 176120 MW; E517CBE251A2999F CRC64; MGNTLDSNKP KNFVTYADYK YIGKLNNKNE HHGIGIILYN SGESFYGSFI NGKKEGKGIY IDKNLTRYIN TWVDNKVFGK VKVVPYNSNR VYYFYYKNYM IEKCIYFDNN INNKESHHKN NIYNNYDNNS YNNNSCDDEE KRKYPIGVTK FKEDLSNYIH STHIMKKNNK LFNKNDNEYN IFSSSLSYSS DSENINLLDI LKKKKNKKNK KNKKKKNKKT KNTQILSCTQ HKMYEHNMNE SNFTKKDNVN CEHTDKMNIS LHEKNDKKNE KKNEKKNKKK KLFKYFSNNI ENLIIENYQT WSLREVIQWL MLCNVPVKWL ISFYKNNITG DKLKYININT IRNELGIIAY GHAIKILQLI KNLQVMAYNK KFNNLIQIEE YKNYIRQKEN TNKNIKKGKN IKKEKKKKKE KNIKKEKKKK KKETKKFNNM DKKYIDLAIH KNVKNIQNDT FYNKHENIYN CKNQTNFIYQ NDSEIKKIMN KKKVSFEYDN NEEKKKKNII KFIKNNKSLQ NSNGEYYLIN HLSKGICSDS IFYKSSQSKS SSQLSSPLSS PLSSPSPSSS PSSSPSSSPS SSPSSSPSPS SSPSPSSSPS SSPSSSPSSP PSPLSYKDNF PISSSCSSLE RLPSYEKKLL SSSQSNIEHI KNLPLDVLSN NNSSANIKIK KSKSKYNNDK KEQKKLPLIL NKSSSEFSPS HSYTSKSYHY NIKPSLQSSS NNSSDSSYSI SSTCSSSSSY VSSLYSNRSN DILNFYRNKI IKYCNNIYMN TKLAYSYMNG FIIPHEDLIF IHPIENYYMD NTNEKNNINN PYTKEKIMNH NFSFNTKNNT SFIDINTNIF SSNKQQNINN FGKYKKMKSR MFKGKYMGKE VAIKILVGKI KNFKKLHQIL YNLYNLRHSN LVLIMGVSIH YPFVFIIYEY MKNKCLFSYL HCIKYKHVYI STFLQRYKTL LHITQQEKIK KTNNINNNNN INHNNINNNN INHNNINHNN INNNNINNNN INYNKDYNNK KKKEDEQHNI EHQDTFIDLP EKSNISSDDN NSTDISQIQK ENFHFLNKKI EENKNIIYDD HTSTLSDHSI HNINKSYDNV YKNKMNIFHY QHNVLCGAYD NNDNNINDND IYCNNIYDNN INDNHIYCNN INDNHIYCNN INDNHIYCNN IYDHHKNTSL NSKEQNTDHN IEQINECNKY ASETKYNIKK SNLKNNIISH KNFQKCNQIQ MNQPYTFPPY QKELSSYLKN EKIKRKRKVL FSYLKTHIHF NSQQINDQHN RLSVQKIMKI ITDVTLACTY LEKEKMSPIN LKPTNILLDE SLNAKISDFG ISKIENCLDM NIDYSYKISS NSVIKINKKE YEQKKAKKIK IVNKNNNDLL YLYDHNNNVY KYNTQYIDVT YNNSYPSIFY WTPPEILRGK KNKKFYSDIY AFGIILWEML SNDIPYNYPF ASHIMAVVGY ANEELSFNNI PVSIQSLIKA CVNRNKYKRP TFEHILKTIS TLYQKANTKV EDALISFMDG T //