ID NDHI_LOXSI Reviewed; 166 AA. AC Q8HVQ0; DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot. DT 01-MAR-2003, sequence version 1. DT 03-OCT-2012, entry version 61. DE RecName: Full=NAD(P)H-quinone oxidoreductase subunit I, chloroplastic; DE EC=1.6.5.-; DE AltName: Full=NAD(P)H dehydrogenase subunit I; DE Short=NDH subunit I; DE AltName: Full=NADH-plastoquinone oxidoreductase subunit I; GN Name=ndhI; OS Loxothysanus sinuatus. OG Plastid; Chloroplast. OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; OC asterids; campanulids; Asterales; Asteraceae; Asteroideae; OC Heliantheae alliance; Bahieae; Loxothysanus. OX NCBI_TaxID=176551; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RA Panero J.L., Baldwin B.G., Schilling E.E., Clevinger J.A.; RT "Chloroplast DNA phylogeny of tribe Heliantheae (Asteraceae)."; RL Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: NDH shuttles electrons from NAD(P)H:plastoquinone, via CC FMN and iron-sulfur (Fe-S) centers, to quinones in the CC photosynthetic chain and possibly in a chloroplast respiratory CC chain. The immediate electron acceptor for the enzyme in this CC species is believed to be plastoquinone. Couples the redox CC reaction to proton translocation, and thus conserves the redox CC energy in a proton gradient (By similarity). CC -!- CATALYTIC ACTIVITY: NAD(P)H + plastoquinone = NAD(P)(+) + CC plastoquinol. CC -!- COFACTOR: Binds 2 4Fe-4S clusters per subunit (By similarity). CC -!- SUBUNIT: NDH is composed of at least 16 different subunits, 5 of CC which are encoded in the nucleus (By similarity). CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane; CC Peripheral membrane protein (By similarity). CC -!- SIMILARITY: Belongs to the complex I 23 kDa subunit family. CC -!- SIMILARITY: Contains 2 4Fe-4S ferredoxin-type domains. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF383813; AAN61754.1; -; Genomic_DNA. DR HSSP; P00193; 1DUR. DR ProteinModelPortal; Q8HVQ0; -. DR GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell. DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro. DR GO; GO:0048038; F:quinone binding; IEA:UniProtKB-KW. DR Gene3D; G3DSA:1.10.1060.10; Fum_reductase_C; 1. DR HAMAP; MF_01351; NDH1_NuoI; 1; -. DR InterPro; IPR017896; 4Fe4S_Fe-S-bd. DR InterPro; IPR017900; 4Fe4S_Fe_S_CS. DR InterPro; IPR012285; Fum_reductase_C. DR InterPro; IPR004497; NADH_plast_OxRdtase_su_I. DR InterPro; IPR010226; NADH_quinone_OxRdtase_chainI. DR TIGRFAMs; TIGR00403; ndhI; 1. DR TIGRFAMs; TIGR01971; NuoI; 1. DR PROSITE; PS00198; 4FE4S_FER_1; 2. DR PROSITE; PS51379; 4FE4S_FER_2; 2. PE 3: Inferred from homology; KW 4Fe-4S; Chloroplast; Iron; Iron-sulfur; Membrane; Metal-binding; NAD; KW NADP; Oxidoreductase; Plastid; Plastoquinone; Quinone; Repeat; KW Thylakoid. FT CHAIN 1 166 NAD(P)H-quinone oxidoreductase subunit I, FT chloroplastic. FT /FTId=PRO_0000250811. FT DOMAIN 55 84 4Fe-4S ferredoxin-type 1. FT DOMAIN 95 124 4Fe-4S ferredoxin-type 2. FT METAL 64 64 Iron-sulfur 1 (4Fe-4S) (By similarity). FT METAL 67 67 Iron-sulfur 1 (4Fe-4S) (By similarity). FT METAL 70 70 Iron-sulfur 1 (4Fe-4S) (By similarity). FT METAL 74 74 Iron-sulfur 2 (4Fe-4S) (By similarity). FT METAL 104 104 Iron-sulfur 2 (4Fe-4S) (By similarity). FT METAL 107 107 Iron-sulfur 2 (4Fe-4S) (By similarity). FT METAL 110 110 Iron-sulfur 2 (4Fe-4S) (By similarity). FT METAL 114 114 Iron-sulfur 1 (4Fe-4S) (By similarity). SQ SEQUENCE 166 AA; 19509 MW; 51D18659EA31BED7 CRC64; MFPMVTEFMN YGQQTVRAAR YIGQGFMITL SHANRLPVTI QYPYEKLITS ERFRGRIHFE FDKCIACEVC VRVCPIDLPV VDWKLETDIR KKRLLNYSID FGICIFCGNC VEYCPTNCLS MTEEYELSTY DRHELNYNQI ALGRLPMSII DDYTIRTIFN LPEIKT //