ID Q8HBS8_9SAUR PRELIMINARY; PRT; 170 AA. AC Q8HBS8; DT 01-MAR-2003 (TrEMBLrel. 23, Created) DT 01-MAR-2003 (TrEMBLrel. 23, Last sequence update) DT 01-FEB-2005 (TrEMBLrel. 29, Last annotation update) DE Cytochrome c oxidase subunit I (Fragment). GN Name=COI; OS Orthriophis taeniurus. OG Mitochondrion. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Lepidosauria; Squamata; Scleroglossa; Serpentes; Colubroidea; OC Colubridae; Colubrinae; Orthriophis. OX NCBI_TaxID=74398; RN [1] RP NUCLEOTIDE SEQUENCE. RA Utiger U., Helfenberger N., Schaetti B., Schmidt C., Ruf M., RA Ziswiler V.; RT "Molecular systematics and phylogeny of Old and New World ratsnakes, RT Elaphe auct., and related genera (Reptilia, Squamata, Colubridae)."; RL Russ. J. Herpetol. 9:105-124(2002). CC -!- FUNCTION: Cytochrome c oxidase is the component of the respiratory CC chain that catalyzes the reduction of oxygen to water. Subunits 1- CC 3 form the functional core of the enzyme complex. CO I is the CC catalytic subunit of the enzyme. Electrons originating in CC cytochrome c are transferred via the copper A center of subunit 2 CC and heme A of subunit 1 to the bimetallic center formed by heme A3 CC and copper B (By similarity). CC -!- CATALYTIC ACTIVITY: 4 ferrocytochrome c + O(2) = 4 ferricytochrome CC c + 2 H(2)O. CC -!- PATHWAY: Respiratory chain; terminal step. CC -!- SUBCELLULAR LOCATION: Integral membrane protein. Mitochondrial CC inner membrane (By similarity). CC -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY122723; AAM81041.1; -. DR EMBL; AY122724; AAM81042.1; -. DR EMBL; AY122725; AAM81043.1; -. DR GO; GO:0019866; C:inner membrane; IEA. DR GO; GO:0016021; C:integral to membrane; IEA. DR GO; GO:0005746; C:mitochondrial electron transport chain; IEA. DR GO; GO:0005739; C:mitochondrion; IEA. DR GO; GO:0004129; F:cytochrome-c oxidase activity; IEA. DR GO; GO:0016491; F:oxidoreductase activity; IEA. DR GO; GO:0006118; P:electron transport; IEA. DR GO; GO:0006810; P:transport; IEA. DR InterPro; IPR000883; COX1. DR Pfam; PF00115; COX1; 1. DR PRINTS; PR01165; CYCOXIDASEI. DR PROSITE; PS50855; COX1; 1. DR PROSITE; PS00077; COX1_CUB; 1. KW Copper; Electron transport; Heme; Inner membrane; Membrane; KW Mitochondrion; Oxidoreductase; Respiratory chain; Transmembrane; KW Transport. FT NON_TER 1 1 FT NON_TER 170 170 SQ SEQUENCE 170 AA; 18510 MW; 6FA06BFE78C547B4 CRC64; AGTGWTVYPP LSGNLVHSGP SVDLAIFSLH LAGASSILGA INFITTCINM KPKSMPMFNI PLFVWSVLIT AIMLLLALPV LAAAITMLLT DRNLNTSFFD PCGGGDPVLF QHLFWFFGHP EVYILILPGF GIVSSIITFY TGKKNTFGYT SMIWAMMSIA ILGFVVWAHH //