ID SRR1_ARATH Reviewed; 275 AA. AC Q8GWZ6; Q9LTH5; DT 30-MAY-2003, integrated into UniProtKB/Swiss-Prot. DT 30-MAY-2003, sequence version 2. DT 31-OCT-2006, entry version 31. DE Protein SENSITIVITY TO RED LIGHT REDUCED 1. GN Name=SRR1; OrderedLocusNames=At5g59560; ORFNames=F2O15.23, F2O15.220; OS Arabidopsis thaliana (Mouse-ear cress). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; OC rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis. OX NCBI_TaxID=3702; RN [1] RP NUCLEOTIDE SEQUENCE, FUNCTION, SUBCELLULAR LOCATION, AND INDUCTION. RC STRAIN=cv. Columbia; RX MEDLINE=22421268; PubMed=12533513; DOI=10.1101/gad.244103; RA Staiger D., Allenbach L., Salathia N., Fiechter V., Davis S.J., RA Millar A.J., Chory J., Fankhauser C.; RT "The Arabidopsis SRR1 gene mediates phyB signaling and is required for RT normal circadian clock function."; RL Genes Dev. 17:256-268(2003). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Columbia; RX MEDLINE=21016721; PubMed=11130714; DOI=10.1038/35048507; RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., RA Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., RA Nakazaki N., Naruo K., Okumura S., Shinpo S., Takeuchi C., Wada T., RA Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., RA Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., RA Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., RA Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., RA Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., RA Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., RA Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., RA Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., RA Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., RA Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., RA Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., RA Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., RA van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., RA Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., RA Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., RA Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., RA Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.; RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis RT thaliana."; RL Nature 408:823-826(2000). RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., RA Feldmann K.A.; RT "Full-length cDNA from Arabidopsis thaliana."; RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases. RN [4] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 206-275. RC STRAIN=cv. Columbia; RX MEDLINE=21932900; PubMed=11910074; DOI=10.1126/science.1071006; RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T., RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., RA Hayashizaki Y., Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., RA Shibata K., Shinagawa A., Shinozaki K.; RT "Functional annotation of a full-length Arabidopsis cDNA collection."; RL Science 296:141-145(2002). CC -!- FUNCTION: Probable regulator involved in a circadian clock input CC pathway, which is required for normal oscillator function. CC Regulates the expression of clock-regulated genes such as CCA1 and CC TOC1. Involved in both the phytochrome B (PHYB) and PHYB- CC independent signaling pathways. CC -!- SUBCELLULAR LOCATION: Cytoplasm. Nucleus. CC -!- INDUCTION: By light. Not modulated by far-red light. CC -!- SIMILARITY: Belongs to the SRR1 family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY127047; AAM97478.1; -; mRNA. DR EMBL; AB025604; BAA97490.1; -; Genomic_DNA. DR EMBL; AY084714; AAM61288.1; -; mRNA. DR EMBL; AK118532; BAC43135.1; ALT_INIT; mRNA. DR UniGene; At.28233; -. DR TAIR; At5g59560; -. DR LinkHub; Q8GWZ6; -. DR ArrayExpress; Q8GWZ6; -. DR GO; GO:0005737; C:cytoplasm; IDA:UniProtKB. DR GO; GO:0005634; C:nucleus; IDA:UniProtKB. DR GO; GO:0007623; P:circadian rhythm; IMP:UniProtKB. DR GO; GO:0010017; P:red or far red light signaling pathway; IMP:UniProtKB. DR InterPro; IPR012942; SRR1. DR Pfam; PF07985; SRR1; 1. KW Biological rhythms; Nuclear protein; Phytochrome signaling pathway. FT CHAIN 1 275 Protein SENSITIVITY TO RED LIGHT REDUCED FT 1. FT /FTId=PRO_0000186122. FT MOTIF 26 29 Nuclear localization signal (Potential). FT COMPBIAS 37 40 Poly-Glu. FT CONFLICT 207 207 G -> V (in Ref. 4). FT CONFLICT 209 210 SF -> RS (in Ref. 4). SQ SEQUENCE 275 AA; 31475 MW; 4FBE65C784CFFB4E CRC64; METTVKNSSS DGEWKVVLPS KGRQGRRRKP KPKGQAEEEE QPWKSDDLEI DPQRQARLKQ KMEISLKKIE SSSFYTAFLE QLKSPEVSNQ IRLVLGSETQ LQMVMYGIGS IESYESPRFQ LSIAILMKRE FDWVGDNIEV FDPVLSATES SYLESLGCSV LSVNEQARRE ALKPTLFFMP HCEANLYSNL LQANWRMDRL SKIALFGNSF QMYEEQVSFD AEVICATKRI IAAQRVTSEF AIETESDDYF AAFHDSSWHF FSSGIDSELP LFVSD //