ID Q8F9P1_LEPIN Unreviewed; 606 AA. AC Q8F9P1; DT 01-MAR-2003, integrated into UniProtKB/TrEMBL. DT 01-MAR-2003, sequence version 1. DT 10-APR-2019, entry version 112. DE SubName: Full=ATPase and permease components of ABC-type multidrug transport system {ECO:0000313|EMBL:AAN47349.1}; GN Name=mdlB {ECO:0000313|EMBL:AAN47349.1}; GN OrderedLocusNames=LA_0150 {ECO:0000313|EMBL:AAN47349.1}; OS Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai OS (strain 56601). OC Bacteria; Spirochaetes; Leptospirales; Leptospiraceae; Leptospira. OX NCBI_TaxID=189518 {ECO:0000313|EMBL:AAN47349.1, ECO:0000313|Proteomes:UP000001408}; RN [1] {ECO:0000313|EMBL:AAN47349.1, ECO:0000313|Proteomes:UP000001408} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=56601 {ECO:0000313|EMBL:AAN47349.1, RC ECO:0000313|Proteomes:UP000001408}; RX PubMed=12712204; DOI=10.1038/nature01597; RA Ren S.X., Fu G., Jiang X.G., Zeng R., Miao Y.G., Xu H., Zhang Y.X., RA Xiong H., Lu G., Lu L.F., Jiang H.Q., Jia J., Tu Y.F., Jiang J.X., RA Gu W.Y., Zhang Y.Q., Cai Z., Sheng H.H., Yin H.F., Zhang Y., Zhu G.F., RA Wan M., Huang H.L., Qian Z., Wang S.Y., Ma W., Yao Z.J., Shen Y., RA Qiang B.Q., Xia Q.C., Guo X.K., Danchin A., Saint Girons I., RA Somerville R.L., Wen Y.M., Shi M.H., Chen Z., Xu J.G., Zhao G.P.; RT "Unique physiological and pathogenic features of Leptospira RT interrogans revealed by whole-genome sequencing."; RL Nature 422:888-893(2003). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE010300; AAN47349.1; -; Genomic_DNA. DR RefSeq; NP_710331.1; NC_004342.2. DR RefSeq; WP_000828456.1; NC_004342.2. DR ProteinModelPortal; Q8F9P1; -. DR EnsemblBacteria; AAN47349; AAN47349; LA_0150. DR GeneID; 1149493; -. DR KEGG; lil:LA_0150; -. DR PATRIC; fig|189518.3.peg.154; -. DR eggNOG; ENOG4105BZ1; Bacteria. DR eggNOG; COG1132; LUCA. DR HOGENOM; HOG000271742; -. DR KO; K06147; -. DR OMA; FSYLWFM; -. DR BioCyc; LINT189518:G1GL4-137-MONOMER; -. DR Proteomes; UP000001408; Chromosome I. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule. DR GO; GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro. DR Gene3D; 1.20.1560.10; -; 1. DR InterPro; IPR003593; AAA+_ATPase. DR InterPro; IPR011527; ABC1_TM_dom. DR InterPro; IPR036640; ABC1_TM_sf. DR InterPro; IPR003439; ABC_transporter-like. DR InterPro; IPR017871; ABC_transporter_CS. DR InterPro; IPR027417; P-loop_NTPase. DR InterPro; IPR039421; Type_I_exporter. DR PANTHER; PTHR24221; PTHR24221; 1. DR Pfam; PF00664; ABC_membrane; 1. DR Pfam; PF00005; ABC_tran; 1. DR SMART; SM00382; AAA; 1. DR SUPFAM; SSF52540; SSF52540; 1. DR SUPFAM; SSF90123; SSF90123; 1. DR PROSITE; PS50929; ABC_TM1F; 1. DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1. DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1. PE 4: Predicted; KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00434}; KW Complete proteome {ECO:0000313|Proteomes:UP000001408}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00434}; KW Reference proteome {ECO:0000313|Proteomes:UP000001408}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 63 80 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 100 120 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 174 197 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 203 222 Helical. {ECO:0000256|SAM:Phobius}. FT TRANSMEM 294 311 Helical. {ECO:0000256|SAM:Phobius}. FT DOMAIN 64 346 ABC transmembrane type-1. FT {ECO:0000259|PROSITE:PS50929}. FT DOMAIN 379 606 ABC transporter. {ECO:0000259|PROSITE: FT PS50893}. FT NP_BIND 412 419 ATP. {ECO:0000256|PROSITE-ProRule: FT PRU00434}. SQ SEQUENCE 606 AA; 68077 MW; AF79FD8E10CB5F1B CRC64; MKRPLEYNPE LIQKSEPLPE KGSSKKWKVP NPKKEKAGSE TEGAPSLLIF GLFRFAKKYK GRIFLIIGLL CFEIGFYASI PFSFKYLIDE ALINRNQNAL YWIGAYLAIG TIAFAILGTL RDYLYNWASA RIIQDLRLQM YEHLDQLSLD FFSNNKLGDI LSRFFNDLTA LEHALLAFIP WGLGPLLEAV FGTILLFLLD WKLALIALLI WPISFLGPGF LSRKSTEISY TRKLEEAQVL SLVEESISAQ NLIRAYDLSD YFFARFKNNC EKLFQVSLRL GLTNSYLERS AGSGILLLQG VLLLVGTIFA YHNTLSIGTL AAFLPPFLNL SYSLLYLSQY LPALNHASGS AKRILELLRT PVFESNPEES SIPELKEAIH FENVHFRYKG RSKNLSDITL TISKGSYTAI VGGSGVGKST FIKLLLGMVQ PNEGRILFDG MDINLLSRSS VRSLVGVVFQ ETFLFNTTIF ENIRIGKPSA TLEEVIEAAK RAEIHETILS LPMGYETNAG DRGTKLSGGE RQRIAIARAF LRNPQILLLD EATSSLDPVT EARIMKTLSL LREGRTVISV THRLSTIREA DQVFQMRNGK LERFSVPEPE QQAMVL //