ID GSDC3_MOUSE Reviewed; 480 AA. AC Q8CB12; DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot. DT 01-MAR-2003, sequence version 1. DT 28-JUN-2011, entry version 50. DE RecName: Full=Gasdermin-C3; GN Name=Gsdmc3; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=C57BL/6J; TISSUE=Vagina; RX PubMed=16141072; DOI=10.1126/science.1112014; RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., RA Davis M.J., Wilming L.G., Aidinis V., Allen J.E., RA Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., RA Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., RA Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., RA Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., RA di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., RA Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., RA Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., RA Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., RA Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., RA Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., RA Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., RA Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., RA Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., RA Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., RA Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., RA Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., RA Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., RA Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., RA Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., RA Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., RA Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., RA Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., RA Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., RA Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., RA Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., RA Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., RA Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., RA Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., RA Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., RA Hayashizaki Y.; RT "The transcriptional landscape of the mammalian genome."; RL Science 309:1559-1563(2005). RN [2] RP IDENTIFICATION. RX PubMed=17350798; DOI=10.1016/j.ygeno.2007.01.003; RA Tamura M., Tanaka S., Fujii T., Aoki A., Komiyama H., Ezawa K., RA Sumiyama K., Sagai T., Shiroishi T.; RT "Members of a novel gene family, Gsdm, are expressed exclusively in RT the epithelium of the skin and gastrointestinal tract in a highly RT tissue-specific manner."; RL Genomics 89:618-629(2007). CC -!- SIMILARITY: Belongs to the gasdermin family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AK037079; BAC29694.1; -; mRNA. DR IPI; IPI00621324; -. DR RefSeq; NP_899017.2; NM_183194.3. DR UniGene; Mm.483471; -. DR PRIDE; Q8CB12; -. DR GeneID; 270328; -. DR KEGG; mmu:270328; -. DR UCSC; uc007vza.1; mouse. DR CTD; 270328; -. DR MGI; MGI:3580656; Gsdmc3. DR eggNOG; roNOG15788; -. DR GeneTree; ENSGT00530000063218; -. DR HOGENOM; HBG282447; -. DR HOVERGEN; HBG107969; -. DR InParanoid; Q8CB12; -. DR OrthoDB; EOG43R3NK; -. DR NextBio; 393321; -. DR ArrayExpress; Q8CB12; -. DR Bgee; Q8CB12; -. DR Genevestigator; Q8CB12; -. DR InterPro; IPR007677; Gasdermin. DR PANTHER; PTHR16399; DFNA5; 1. DR Pfam; PF04598; Gasdermin; 1. PE 2: Evidence at transcript level; KW Complete proteome. FT CHAIN 1 480 Gasdermin-C3. FT /FTId=PRO_0000347332. SQ SEQUENCE 480 AA; 54192 MW; 0AAFF05923942CC0 CRC64; MGYSFDRASK DVVKKLQGRD LRPVECLSDA TKFRLFHILQ ETPRSGWETE DIPVGFTLLD LLEPNFPVPE PEVSAPKPFI HVQSTDLEAN LNVADIARGG VGYVGYGGYN IEVQSTSIPN PKLEILQNRK LLDKLPTFMK FCRMERKNLY VVTEAYEVSK DTMLTGLSSV NLLVKGFFKQ LFKVRGKAGR SEKYSIPIPK GSVLAYKKQQ LVIENNTCVI LPSATKKKMT FPGTPKYASA SEPTEIYRTE LQGLWINDIE PIGRIQEPAH LDFKCLQYEV SEQTRLLPEL SKDVQEVVLS SFLSMLYEGD RNVLHDLMKM LELSQLGHMD GPGGKILDEL RKDSSNPCVD LKDLILYLLQ ALMVLSDSQL NLLARSVEMR LLTHQVELVT SILQPNFKYP WNIPFTVQPQ LLAPLQGEGL AITYELLEEC GLKMELNNPR STWDLEAKMP LSALYGSLSF LQQLQKANSS FKPSLRPGYI //