ID ADCL4_MOUSE Reviewed; 407 AA. AC Q8BM81; DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot. DT 12-DEC-2006, sequence version 2. DT 01-SEP-2009, entry version 45. DE RecName: Full=Arylacetamide deacetylase-like 4; DE EC=3.1.1.-; GN Name=Aadacl4; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=C57BL/6J; TISSUE=Embryo; RX PubMed=16141072; DOI=10.1126/science.1112014; RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., RA Davis M.J., Wilming L.G., Aidinis V., Allen J.E., RA Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., RA Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., RA Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., RA Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., RA di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., RA Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., RA Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., RA Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., RA Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., RA Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., RA Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., RA Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., RA Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., RA Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., RA Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., RA Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., RA Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., RA Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., RA Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., RA Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., RA Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., RA Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., RA Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., RA Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., RA Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., RA Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., RA Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., RA Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., RA Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., RA Hayashizaki Y.; RT "The transcriptional landscape of the mammalian genome."; RL Science 309:1559-1563(2005). CC -!- SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein CC (Potential). CC -!- SIMILARITY: Belongs to the 'GDXG' lipolytic enzyme family. CC -!- SEQUENCE CAUTION: CC Sequence=BAC28757.1; Type=Erroneous termination; Positions=361; Note=Translated as Glu; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AK034567; BAC28757.1; -; mRNA. DR IPI; IPI00387222; -. DR RefSeq; NP_941064.2; -. DR UniGene; Mm.184290; -. DR MEROPS; S09.968; -. DR PRIDE; Q8BM81; -. DR Ensembl; ENSMUST00000030328; ENSMUSP00000030328; ENSMUSG00000028593; Mus musculus. DR GeneID; 381572; -. DR KEGG; mmu:381572; -. DR UCSC; uc008vrh.1; mouse. DR MGI; MGI:2685880; 9430007A20Rik. DR HOVERGEN; Q8BM81; -. DR OMA; Q8BM81; ITCICKY. DR NextBio; 402262; -. DR ArrayExpress; Q8BM81; -. DR Bgee; Q8BM81; -. DR CleanEx; MM_9430007A20RIK; -. DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. DR GO; GO:0008152; P:metabolic process; IEA:InterPro. DR InterPro; IPR013094; AB_hydrolase_3. DR InterPro; IPR002168; Lipase_GDXG_AS. DR Pfam; PF07859; Abhydrolase_3; 1. DR PROSITE; PS01173; LIPASE_GDXG_HIS; FALSE_NEG. DR PROSITE; PS01174; LIPASE_GDXG_SER; FALSE_NEG. PE 2: Evidence at transcript level; KW Glycoprotein; Hydrolase; Membrane; Signal-anchor; Transmembrane. FT CHAIN 1 407 Arylacetamide deacetylase-like 4. FT /FTId=PRO_0000265938. FT TOPO_DOM 1 4 Cytoplasmic (Potential). FT TRANSMEM 5 25 Signal-anchor for type II membrane FT protein (Potential). FT TOPO_DOM 26 407 Lumenal (Potential). FT ACT_SITE 119 119 Potential. FT ACT_SITE 193 193 Potential. FT CARBOHYD 168 168 N-linked (GlcNAc...) (Potential). SQ SEQUENCE 407 AA; 46220 MW; 22153AF5490E7CD1 CRC64; MLYLVGFLLA TVCLLVLGVN VWVLIDHFLT IDVPPSIPHP VKFRILHFCF HLTTTWGHIL EKMNICSMPQ FFCFLQDSLS SKENHGVFVK DLRFGTIPVR LFRPKAASSK PRRGILFFHG GGAMIGSLDS HHNLCTFLAR ETDSVLVSVG YRKLPYYHHP SLYHDCINAS IHFLKSLKAY GIDPSRVVIC GESIGGAAAV VVTQTLLSRT DIPKIRAQVL IYPILQAFYF QSPSHLMHKN IPFLTKDFMI TCICKYLAID FSWKDAMLTG ACISPSAWKK YEKWLSPDNI PKRFRTTYQP PESPAPFNEA AYLETKHAMN IDISPLVADD KIIAQLPEAF LVSLHWDIIR DDVLLYKKRL EDQGVPVTWH HVEDGFHGCI LLFDKKLFSF PCSLNIVNAV VSYIKDL //