ID Q8BLR3_MOUSE Unreviewed; 374 AA. AC Q8BLR3; DT 01-MAR-2003, integrated into UniProtKB/TrEMBL. DT 01-MAR-2003, sequence version 1. DT 02-OCT-2024, entry version 107. DE RecName: Full=PHD-type domain-containing protein {ECO:0000259|PROSITE:PS51805}; DE Flags: Fragment; GN Name=Kdm4b {ECO:0000313|MGI:MGI:2442355}; GN Synonyms=Jmjd2b {ECO:0000313|MGI:MGI:2442355}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|EMBL:BAC31617.1}; RN [1] {ECO:0000313|EMBL:BAC31617.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAC31617.1}; RC TISSUE=Cortex {ECO:0000313|EMBL:BAC31617.1}; RX PubMed=10349636; DOI=10.1016/S0076-6879(99)03004-9; RA Carninci P., Hayashizaki Y.; RT "High-efficiency full-length cDNA cloning."; RL Methods Enzymol. 303:19-44(1999). RN [2] {ECO:0000313|EMBL:BAC31617.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAC31617.1}; RC TISSUE=Cortex {ECO:0000313|EMBL:BAC31617.1}; RX PubMed=11042159; DOI=10.1101/gr.145100; RA Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., RA Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.; RT "Normalization and subtraction of cap-trapper-selected cDNAs to prepare RT full-length cDNA libraries for rapid discovery of new genes."; RL Genome Res. 10:1617-1630(2000). RN [3] {ECO:0000313|EMBL:BAC31617.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAC31617.1}; RC TISSUE=Cortex {ECO:0000313|EMBL:BAC31617.1}; RX PubMed=11076861; DOI=10.1101/gr.152600; RA Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., RA Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., RA Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A., Yamamoto R., RA Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., RA Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., RA Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., RA Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.; RT "RIKEN integrated sequence analysis (RISA) system--384-format sequencing RT pipeline with 384 multicapillary sequencer."; RL Genome Res. 10:1757-1771(2000). RN [4] {ECO:0000313|EMBL:BAC31617.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAC31617.1}; RC TISSUE=Cortex {ECO:0000313|EMBL:BAC31617.1}; RX PubMed=11217851; DOI=10.1038/35055500; RG The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium; RT "Functional annotation of a full-length mouse cDNA collection."; RL Nature 409:685-690(2001). RN [5] {ECO:0000313|EMBL:BAC31617.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAC31617.1}; RC TISSUE=Cortex {ECO:0000313|EMBL:BAC31617.1}; RA Adachi J., Aizawa K., Akimura T., Arakawa T., Bono H., Carninci P., RA Fukuda S., Furuno M., Hanagaki T., Hara A., Hashizume W., Hayashida K., RA Hayatsu N., Hiramoto K., Hiraoka T., Hirozane T., Hori F., Imotani K., RA Ishii Y., Itoh M., Kagawa I., Kasukawa T., Katoh H., Kawai J., Kojima Y., RA Kondo S., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., RA Miyazaki A., Murata M., Nakamura M., Nishi K., Nomura K., Numazaki R., RA Ohno M., Ohsato N., Okazaki Y., Saito R., Saitoh H., Sakai C., Sakai K., RA Sakazume N., Sano H., Sasaki D., Shibata K., Shinagawa A., Shiraki T., RA Sogabe Y., Tagami M., Tagawa A., Takahashi F., Takaku-Akahira S., RA Takeda Y., Tanaka T., Tomaru A., Toya T., Yasunishi A., Muramatsu M., RA Hayashizaki Y.; RL Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. RN [6] {ECO:0000313|EMBL:BAC31617.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAC31617.1}; RC TISSUE=Cortex {ECO:0000313|EMBL:BAC31617.1}; RX PubMed=12466851; DOI=10.1038/nature01266; RG The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team; RT "Analysis of the mouse transcriptome based on functional annotation of RT 60,770 full-length cDNAs."; RL Nature 420:563-573(2002). RN [7] {ECO:0000313|EMBL:BAC31617.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAC31617.1}; RC TISSUE=Cortex {ECO:0000313|EMBL:BAC31617.1}; RG The FANTOM Consortium; RG Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group); RT "The Transcriptional Landscape of the Mammalian Genome."; RL Science 309:1559-1563(2005). RN [8] {ECO:0000313|EMBL:BAC31617.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J {ECO:0000313|EMBL:BAC31617.1}; RC TISSUE=Cortex {ECO:0000313|EMBL:BAC31617.1}; RX PubMed=16141073; DOI=10.1126/science.1112009; RG RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium; RT "Antisense Transcription in the Mammalian Transcriptome."; RL Science 309:1564-1566(2005). CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AK043678; BAC31617.1; -; mRNA. DR AlphaFoldDB; Q8BLR3; -. DR AGR; MGI:2442355; -. DR MGI; MGI:2442355; Kdm4b. DR ChiTaRS; Kdm4b; mouse. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:TreeGrafter. DR CDD; cd20464; Tudor_JMJD2B_rpt1; 1. DR Gene3D; 2.30.30.140; -; 1. DR Gene3D; 3.10.330.70; -; 1. DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2. DR InterPro; IPR034732; EPHD. DR InterPro; IPR050701; Histone_Mod_Regulator. DR InterPro; IPR040477; KDM4-like_Tudor. DR InterPro; IPR002999; Tudor. DR InterPro; IPR047483; Tudor_KDM4B_rpt1. DR InterPro; IPR011011; Znf_FYVE_PHD. DR InterPro; IPR001965; Znf_PHD. DR InterPro; IPR019787; Znf_PHD-finger. DR InterPro; IPR013083; Znf_RING/FYVE/PHD. DR PANTHER; PTHR13793:SF132; PHD FINGER PROTEIN RHINOCEROS; 1. DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1. DR Pfam; PF13831; PHD_2; 1. DR Pfam; PF18104; Tudor_2; 2. DR Pfam; PF13832; zf-HC5HC2H_2; 1. DR SMART; SM00249; PHD; 2. DR SMART; SM00333; TUDOR; 2. DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1. DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 2. DR PROSITE; PS51805; EPHD; 1. PE 2: Evidence at transcript level; KW Metal-binding {ECO:0000256|ARBA:ARBA00022723}; KW Nucleus {ECO:0000256|ARBA:ARBA00023242}; KW Repeat {ECO:0000256|ARBA:ARBA00022737}; KW Zinc {ECO:0000256|ARBA:ARBA00022833}; KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}. FT DOMAIN 70..183 FT /note="PHD-type" FT /evidence="ECO:0000259|PROSITE:PS51805" FT REGION 312..331 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:BAC31617.1" SQ SEQUENCE 374 AA; 41590 MW; 56A9FCE7CD35B75B CRC64; RPLIPEMCFT SSGENTEPLP ANSYVGEDGT SPLISCAHCC LQVHASCYGV RPELAKEGWT CSRCAAHAWT AECCLCNLRG GALQRTTEHR WIHVICAIAV PEVRFLNVIE RNPVDVSAIP EQRWKLKCIY CRKRMKRVSG ACIQCSYEHC STSFHVTCAH AAGVLMEPDD WPYVVSITCL KHRASGAGGQ LLRTVSLGQI VITKNRNGLY YRCRVIGTTA QTFYEVNFDD GSYSDNLYPE SITSRDCLRL GPPPEGELVE LRWTDGNLYR ARFISMATSL IYQVEFEDGS QLTVKRGDIF TLEEELPKRV RSRLSLSTGT PQEPSFSGDD VKAAKRPRVA SVLATTTEDT GRSPEYLSFM ESLLQAQGRP GAPF //