ID VME1_CVP67 STANDARD; PRT; 230 AA. AC Q8BB24; DT 10-OCT-2003 (Rel. 42, Created) DT 10-OCT-2003 (Rel. 42, Last sequence update) DT 10-OCT-2003 (Rel. 42, Last annotation update) DE E1 glycoprotein (Matrix glycoprotein) (Membrane glycoprotein). GN M. OS Porcine hemagglutinating encephalomyelitis virus (strain 67N) OS (HEV-67N). OC Viruses; ssRNA positive-strand viruses, no DNA stage; Nidovirales; OC Coronaviridae; Coronavirus. OX NCBI_TaxID=230237; RN [1] RP SEQUENCE FROM N.A. RX MEDLINE=22222597; PubMed=12237422; RA Sasseville A.M.-J., Boutin M., Gelinas A.-M., Dea S.; RT "Sequence of the 3'-terminal end (8.1 kb) of the genome of porcine RT haemagglutinating encephalomyelitis virus: comparison with other RT haemagglutinating coronaviruses."; RL J. Gen. Virol. 83:2411-2416(2002). CC -!- FUNCTION: Component of the viral envelope that plays a central CC role in virus morphogenesis and assembly via its interactions with CC other viral proteins (By similarity). CC -!- SUBUNIT: Interacts with many viral proteins in infected cells. CC Interacts with envelope E protein in the budding compartment of CC the host cell, which is located between endoplasmic reticulum and CC the Golgi complex. This two proteins are sufficient for the CC formation of virus-like particles. Forms a complex with HE and S CC proteins. Interacts with nucleocapsid N protein. This interaction CC probably participates to the viral mRNA packaging into the virus CC (By similarity). CC -!- SUBCELLULAR LOCATION: Integral membrane protein. Largely embedded CC in the lipid bilayer. In infected cells, it is located in Golgi CC membranes (By similarity). CC -!- SIMILARITY: Belongs to the coronavirus M protein family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY078417; AAL80035.1; -. DR InterPro; IPR002574; Corona_M. DR Pfam; PF01635; Corona_M; 1. KW Envelope protein; Matrix protein; Transmembrane. FT TRANSMEM 25 44 POTENTIAL. FT TRANSMEM 49 71 POTENTIAL. FT TRANSMEM 81 103 POTENTIAL. SQ SEQUENCE 230 AA; 26287 MW; 1820EFAE161F26C4 CRC64; MSSPTTPVPV ISWTADEAIK FLKEWNFSLG IIVLFITIIL QFGYTSRSMF VYVIKMVILW LMWPLTIILT IFNCVYALNN VYLGFSIVFT IVAIIMWVVY FVNSIRLFIR TGSWWSFNPE TNNLMCIDMK GRMYVRPIIE DYHTLTATII RGHLYIQGIK LGTGYSLSDL PAYVTVAKVT HLCTYKRGFL DRIGDTSGFA VYVKSKVGNY RLPSTHKGSG MDTALLRNNI //