ID CYOB_BUCBP STANDARD; PRT; 659 AA. AC Q89AA4; DT 15-JUN-2004 (Rel. 44, Created) DT 15-JUN-2004 (Rel. 44, Last sequence update) DT 15-JUN-2004 (Rel. 44, Last annotation update) DE Ubiquinol oxidase polypeptide I (EC 1.10.3.-) (Cytochrome o subunit 1) DE (Oxidase BO(3) subunit 1) (Cytochrome o ubiquinol oxidase subunit 1). GN CYOB OR BBP416. OS Buchnera aphidicola (subsp. Baizongia pistaciae). OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; OC Enterobacteriaceae; Buchnera. OX NCBI_TaxID=135842; RN [1] RP SEQUENCE FROM N.A. RX PubMed=12522265; DOI=10.1073/pnas.0235981100; RA Van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F., RA Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J., RA Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A.; RT "Reductive genome evolution in Buchnera aphidicola."; RL Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003). CC -!- FUNCTION: Cytochrome o terminal oxidase complex is the component CC of the aerobic respiratory chain that predominates when cells are CC grown at high aeration. This ubiquinol oxidase shows proton pump CC activity across the membrane in addition to the electron transfer CC (By similarity). CC -!- CATALYTIC ACTIVITY: Ubiquinol-8 + O(2) = Ubiquinone-8 + H(2)O. CC -!- COFACTOR: Contains two protoheme IX (heme b55 and b562) and CC copper B (By similarity). CC -!- PATHWAY: Ubiquinol oxidase catalyzes the terminal step in the CC electron transport chain. CC -!- SUBCELLULAR LOCATION: Integral membrane protein (By similarity). CC -!- SIMILARITY: Belongs to the heme-copper respiratory oxidase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE014017; AAO27126.1; -. DR HSSP; P18401; 1FFT. DR InterPro; IPR000883; COX1. DR Pfam; PF00115; COX1; 1. DR PRINTS; PR01165; CYCOXIDASEI. DR PROSITE; PS00077; COX1; 1. KW Oxidoreductase; Respiratory chain; Transmembrane; Heme; Copper; KW Hydrogen ion transport; Complete proteome. FT DOMAIN 1 14 Extracellular (Potential). FT TRANSMEM 15 35 Potential. FT DOMAIN 36 56 Cytoplasmic (Potential). FT TRANSMEM 57 77 Potential. FT DOMAIN 78 109 Extracellular (Potential). FT TRANSMEM 110 130 Potential. FT DOMAIN 131 148 Cytoplasmic (Potential). FT TRANSMEM 149 169 Potential. FT DOMAIN 170 192 Extracellular (Potential). FT TRANSMEM 193 213 Potential. FT DOMAIN 214 235 Cytoplasmic (Potential). FT TRANSMEM 236 256 Potential. FT DOMAIN 257 280 Extracellular (Potential). FT TRANSMEM 281 301 Potential. FT DOMAIN 302 318 Cytoplasmic (Potential). FT TRANSMEM 319 339 Potential. FT DOMAIN 340 350 Extracellular (Potential). FT TRANSMEM 351 371 Potential. FT DOMAIN 372 382 Cytoplasmic (Potential). FT TRANSMEM 383 403 Potential. FT DOMAIN 404 416 Extracellular (Potential). FT TRANSMEM 417 437 Potential. FT DOMAIN 438 459 Cytoplasmic (Potential). FT TRANSMEM 460 480 Potential. FT DOMAIN 481 499 Extracellular (Potential). FT TRANSMEM 500 520 Potential. FT DOMAIN 521 587 Cytoplasmic (Potential). FT TRANSMEM 588 608 Potential. FT DOMAIN 609 609 Extracellular (Potential). FT TRANSMEM 610 630 Potential. FT DOMAIN 631 659 Cytoplasmic (Potential). FT METAL 109 109 Iron (heme B axial ligand) (Probable). FT METAL 287 287 Copper B (Probable). FT METAL 291 291 Copper B (Probable). FT METAL 336 336 Copper B (Probable). FT METAL 337 337 Copper B (Probable). FT METAL 422 422 Iron (heme O axial ligand) (Probable). FT METAL 424 424 Iron (heme B axial ligand) (Probable). FT CROSSLNK 287 291 1'-histidyl-3'-tyrosine (His-Tyr) FT (By similarity). SQ SEQUENCE 659 AA; 75583 MW; 13DD8E19D4F5FC15 CRC64; MFGKLSLNSI PYHDPIIMIT CCVVILVFLV ISIIITIAQK WQYLWNEWCC TVDHKKIAKM YIFLAFIMLF RGFADAIMMR MQQFLVSSYH GNGTGFLPPH HYDQIFTAHG VIMIFFVAMP LVIGLMNFVV PLQIGSRDVA FPFLNNLSLW LTIFSALLMN VSLGIGEFAQ TGWLAYPPLS ELQYSPGVGV DYWIWSLQIS GIGTTLTAIN FLVTIIKMRS SGMNWFKIPV FTWTSFCTNI LIIASFPVLT VSLLLLTLDR YLGFHFFTND FGGNMMMYVN LIWIWGHPEV YILILPVFGI FSEVVATFSS KELFGYTSLI WATIVITILS FIVWLHHFFT MGASANVNAF FGITTMIISI PTGVKIFNWL FTMYRGNVRI NSIMLWTIGF LITFSIGGMA GVLLSLPVID FSLHNSLFLV AHFHNVIIGG VVFGCFAGIT YWFPKLFGFM LSEKWGKRAF WCWFFGFFCA FMPLYALGLM GMTRRLSQNI NPQFHSMLTI AALGTILIFI GIVFQIIQIF VSIRDRNLNR DCSGDPWNGR TLEWSTTSPP PFYNFAVLPI VQFRDSFWES KKSFKSNKLP ILYTSFHMPK NTKFGFLIGF FAFLLGFSAV WYIFWLFFIS FFVIIYLLVI KSLDTNCDYI ISIEEIKEIE KCINIKKMD //