ID Q86Q42_9CARA Unreviewed; 146 AA. AC Q86Q42; DT 01-JUN-2003, integrated into UniProtKB/TrEMBL. DT 01-JUN-2003, sequence version 1. DT 24-JAN-2024, entry version 75. DE RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500}; DE Flags: Fragment; OS Carabus seishinensis. OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Coleoptera; Adephaga; Caraboidea; Carabidae; OC Carabinae; Carabini; Carabina; Carabus; Leptocarabus. OX NCBI_TaxID=103247 {ECO:0000313|EMBL:AAO32299.1}; RN [1] {ECO:0000313|EMBL:AAO32299.1} RP NUCLEOTIDE SEQUENCE. RX AGRICOLA=IND43720374; RA Sota T., Ishikawa R.; RT "Phylogeny and life-history evolution in Carabus (subtribe Carabina: RT Coleoptera, Carabidae) based on sequences of two nuclear genes."; RL Biol. J. Linn. Soc. Lond. 81:135-149(2004). CC -!- FUNCTION: Ligand for members of the frizzled family of seven CC transmembrane receptors. {ECO:0000256|RuleBase:RU003500}. CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular CC matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}. CC -!- SIMILARITY: Belongs to the Wnt family. {ECO:0000256|ARBA:ARBA00005683, CC ECO:0000256|RuleBase:RU003500}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY183647; AAO32299.1; -; Genomic_DNA. DR AlphaFoldDB; Q86Q42; -. DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW. DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro. DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW. DR InterPro; IPR005817; Wnt. DR PANTHER; PTHR12027:SF91; PROTO-ONCOGENE WNT-1; 1. DR PANTHER; PTHR12027; WNT RELATED; 1. DR Pfam; PF00110; wnt; 1. DR SMART; SM00097; WNT1; 1. PE 3: Inferred from homology; KW Developmental protein {ECO:0000256|ARBA:ARBA00022473, KW ECO:0000256|RuleBase:RU003500}; KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530}; KW Secreted {ECO:0000256|ARBA:ARBA00022525}; KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687, KW ECO:0000256|RuleBase:RU003500}. FT REGION 30..95 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 30..64 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:AAO32299.1" FT NON_TER 146 FT /evidence="ECO:0000313|EMBL:AAO32299.1" SQ SEQUENCE 146 AA; 15999 MW; 40E39C07CF431AD6 CRC64; KTCWMRLPAF RVIGDNLKDR FDGASRVMVS NAGSQRGGNN AHSHHGNSAS TNSIGNSIHS NHANTERGQG RKKKHKYGFQ LKPFNPEHKP PGSKDLVYLE PSPGFCEKNP KLGIEGTHGR YCNDTSIGVD GCDLMCCGRG YLTKEI //