ID Q83625_9MONO Unreviewed; 617 AA. AC Q83625; DT 01-NOV-1996, integrated into UniProtKB/TrEMBL. DT 01-NOV-1996, sequence version 1. DT 07-APR-2021, entry version 119. DE RecName: Full=Hemagglutinin glycoprotein {ECO:0000256|ARBA:ARBA00020483}; GN Name=H {ECO:0000313|EMBL:AAT99297.1}; OS Measles morbillivirus. OC Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina; OC Monjiviricetes; Mononegavirales; Paramyxoviridae; Orthoparamyxovirinae; OC Morbillivirus. OX NCBI_TaxID=11234 {ECO:0000313|EMBL:CAA91369.1, ECO:0000313|Proteomes:UP000100252}; RN [1] {ECO:0000313|EMBL:CAA91369.1, ECO:0000313|Proteomes:UP000100252} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Edmonston B {ECO:0000313|EMBL:CAA91369.1}; RX PubMed=2303032; RA Ballart I., Eschle D., Cattaneo R., Schmid A., Metzler M., Chan J., RA Pifko-Hirst S., Udem S.A., Billeter M.A.; RT "Infectious measles virus from cloned cDNA."; RL EMBO J. 9:379-384(1990). RN [2] {ECO:0000313|EMBL:CAA91369.1, ECO:0000313|Proteomes:UP000100252} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Edmonston B {ECO:0000313|EMBL:CAA91369.1}; RX PubMed=8846771; RA Radecke F., Spielhofer P., Schneider H., Kaelin K., Huber M., Doetsch C., RA Christiansen G., Billeter M.A.; RT "Rescue of measles viruses from cloned DNA."; RL EMBO J. 14:5773-5784(1995). RN [3] {ECO:0000313|Proteomes:UP000100252} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=7747453; DOI=10.1006/viro.1995.1214; RA Komase K., Rima B., Pardowitz I., Kunz C., Billeter M.A., ter Meulen V., RA Baczko K.; RT "A comparison of nucleotide sequences of measles virus L genes derived from RT wild-type viruses and SSPE brain tissues."; RL Virology 208:795-799(1995). RN [4] {ECO:0000313|EMBL:CAA91369.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Edmonston B {ECO:0000313|EMBL:CAA91369.1}; RA Billeter M.M.; RL Submitted (OCT-1995) to the EMBL/GenBank/DDBJ databases. RN [5] {ECO:0000313|EMBL:AAV84958.1, ECO:0000313|Proteomes:UP000131292} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Leningrad-4 {ECO:0000313|EMBL:AAV84958.1}; RA Zhao D.; RT "The whole gene sequence of Measles virus."; RL Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases. RN [6] {ECO:0000313|EMBL:AAT99297.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=MVi/Prague.CZH/Havlowa.1/60 {ECO:0000313|EMBL:AAT99297.1}; RX PubMed=15659756; DOI=10.1099/vir.0.80467-0; RA Santibanez S., Niewiesk S., Heider A., Schneider-Schaulies J., RA Berbers G.A., Zimmermann A., Halenius A., Wolbert A., Deitemeier I., RA Tischer A., Hengel H.; RT "Probing neutralizing-antibody responses against emerging measles viruses RT (MVs): immune selection of MV by H protein-specific antibodies?"; RL J. Gen. Virol. 86:365-374(2005). CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single- CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}. Virion CC membrane {ECO:0000256|ARBA:ARBA00004208}; Single-pass type II membrane CC protein {ECO:0000256|ARBA:ARBA00004208}. CC -!- SIMILARITY: Belongs to the paramyxoviruses hemagglutinin-neuraminidase CC family. {ECO:0000256|RuleBase:RU004216}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY685221; AAT99297.1; -; Genomic_RNA. DR EMBL; AY730614; AAV84958.1; -; Genomic_RNA. DR EMBL; Z66517; CAA91369.1; -; Genomic_RNA. DR PIR; PQ0377; PQ0377. DR PIR; PQ0381; PQ0381. DR Proteomes; UP000100252; Genome. DR Proteomes; UP000131292; Genome. DR GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-KW. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0019031; C:viral envelope; IEA:UniProtKB-KW. DR GO; GO:0055036; C:virion membrane; IEA:UniProtKB-SubCell. DR GO; GO:0046789; F:host cell surface receptor binding; IEA:InterPro. DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW. DR GO; GO:0019062; P:virion attachment to host cell; IEA:UniProtKB-KW. DR InterPro; IPR000665; Hemagglutn/HN. DR InterPro; IPR036278; Sialidase_sf. DR Pfam; PF00423; HN; 1. DR SUPFAM; SSF50939; SSF50939; 1. PE 3: Inferred from homology; KW Hemagglutinin {ECO:0000256|ARBA:ARBA00022546, KW ECO:0000256|RuleBase:RU004216}; KW Host-virus interaction {ECO:0000256|ARBA:ARBA00022581}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968}; KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, KW ECO:0000256|SAM:Phobius}; KW Viral attachment to host cell {ECO:0000256|ARBA:ARBA00022804}; KW Viral envelope protein {ECO:0000256|ARBA:ARBA00022879, KW ECO:0000256|RuleBase:RU004216}; KW Virion {ECO:0000256|ARBA:ARBA00022879, ECO:0000256|RuleBase:RU004216}; KW Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}. FT TRANSMEM 36..58 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" SQ SEQUENCE 617 AA; 69220 MW; 0E45DF3EDA43D9C6 CRC64; MSPQRDRINA FYKDNPHPKG SRIVINREHL MIDRPYVLLA VLFVMFLSLI GLLAIAGIRL HRAAIYTAEI HKSLSTNLDV TNSIEHQVKD VLTPLFKIIG DEVGLRTPQR FTDLVKFISD KIKFLNPDRE YDFRDLTWCI NPPERIKLDY DQYCADVAAE ELMNALVNST LLETRTTNQF LAVSKGNCSG PTTIRGQFSN MSLSLLDLYL GRGYNVSSIV TMTSQGMYGG TYLVEKPNLS SKRSELSQLS MYRVFEVGVI RNPGLGAPVF HMTNYLEQPV SNDLSNCMVA LGELKLAALC HGEDSITIPY QGSGKGVSFQ LVKLGVWKSP TDMQSWVPLS TDDPVIDRLY LSSHRGVIAD NQAKWAVPTT RTDDKLRMET CFQQACKGKI QALCENPEWA PLKDNRIPSY GVLSVDLSLT VELKIKIASG FGPLITHGSG MDLYKSNHNN VYWLTIPPMK NLALGVINTL EWIPRFKVSP YLFNVPIKEA GEDCHAPTYL PAEVDGDVKL SSNLVILPGQ DLQYVLATYD TSRVEHAVVY YVYSPSRSFS YFYPFRLPIK GVPIELQVEC FTWDQKLWCR HFCVLADSES GGHITHSGMV GMGVSCTVTR EDGTNRR //