ID   NOC_BACCR               Reviewed;         290 AA.
AC   Q814F9;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   18-APR-2012, entry version 49.
DE   RecName: Full=Nucleoid occlusion protein;
DE            Short=Noc;
GN   Name=noc; OrderedLocusNames=BC_5483;
OS   Bacillus cereus (strain ATCC 14579 / DSM 31).
OC   Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=226900;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 14579 / DSM 31;
RX   MEDLINE=22608415; PubMed=12721630; DOI=10.1038/nature01582;
RA   Ivanova N., Sorokin A., Anderson I., Galleron N., Candelon B.,
RA   Kapatral V., Bhattacharyya A., Reznik G., Mikhailova N., Lapidus A.,
RA   Chu L., Mazur M., Goltsman E., Larsen N., D'Souza M., Walunas T.,
RA   Grechkin Y., Pusch G., Haselkorn R., Fonstein M., Ehrlich S.D.,
RA   Overbeek R., Kyrpides N.C.;
RT   "Genome sequence of Bacillus cereus and comparative analysis with
RT   Bacillus anthracis.";
RL   Nature 423:87-91(2003).
CC   -!- FUNCTION: Effects nucleoid occlusion by binding relatively
CC       nonspecifically to DNA and preventing the assembly of the division
CC       machinery in the vicinity of the nucleoid, especially under
CC       conditions that disturb the cell cycle. It helps to coordinate
CC       cell division and chromosome segregation by preventing the
CC       formation of the Z ring through the nucleoid, which would cause
CC       chromosome breakage (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid (By similarity).
CC   -!- SIMILARITY: Belongs to the parB family.
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DR   EMBL; AE016877; AAP12337.1; -; Genomic_DNA.
DR   RefSeq; NP_835136.1; NC_004722.1.
DR   ProteinModelPortal; Q814F9; -.
DR   STRING; Q814F9; -.
DR   EnsemblBacteria; EBBACT00000031475; EBBACP00000030681; EBBACG00000031466.
DR   GeneID; 1207822; -.
DR   GenomeReviews; AE016877_GR; BC_5483.
DR   KEGG; bce:BC5483; -.
DR   PATRIC; 32607188; VBIBacCer54481_5661.
DR   eggNOG; COG1475; -.
DR   HOGENOM; HBG641230; -.
DR   KO; K03497; -.
DR   OMA; RFQPRTI; -.
DR   ProtClustDB; CLSK873785; -.
DR   BioCyc; BCER226900:BC_5483-MONOMER; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000917; P:barrier septum assembly; IEA:UniProtKB-KW.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   Gene3D; G3DSA:1.10.260.40; G3DSA:1.10.260.40; 1.
DR   HAMAP; MF_02015; ParB_Noc; 1; -.
DR   InterPro; IPR010982; Lambda_DNA-bd.
DR   InterPro; IPR023705; Nucleoid_occlusion_protein.
DR   InterPro; IPR004437; ParB_part.
DR   InterPro; IPR003115; ParBc.
DR   Pfam; PF02195; ParBc; 1.
DR   SMART; SM00470; ParB; 1.
DR   SUPFAM; SSF110849; ParBc; 1.
DR   TIGRFAMs; TIGR00180; ParB_part; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Complete proteome; Cytoplasm; DNA-binding;
KW   Reference proteome; Septation.
FT   CHAIN         1    290       Nucleoid occlusion protein.
FT                                /FTId=PRO_0000346619.
FT   DNA_BIND    153    172       H-T-H motif (Potential).
SQ   SEQUENCE   290 AA;  33618 MW;  B3DE34F7E3F0390B CRC64;
     MKNTFSRLFG FGDKESEFEL QDESHEEIDK KVYEEIQEIP IVNITPNRYQ PRTVFDDARI
     DELALTIRTH GLIQPIVVRQ YEDDKYEIIA GERRFRAATK LGWEKVPAII KNLNDTETAS
     VALIENLQRE ELTAIEEAVA YQKLIELHNL TQEALAQRLG KGQSTIANKL RLLKLPEEIK
     SALLEKSITE RHARALIPLK NEELQLKVLQ EIVEKQLNVK QTEERIAKLL EEAKPKRKAK
     QKAVSRDTRI AMNTIRQSLQ MVTESGLNVN SEEEEFDEYY QITIKIPKKK
//