ID Q80XG0_PERMA Unreviewed; 61 AA. AC Q80XG0; DT 01-JUN-2003, integrated into UniProtKB/TrEMBL. DT 01-JUN-2003, sequence version 1. DT 06-FEB-2007, entry version 19. DE Interleukin-12 p35 subunit (Fragment). GN Name=Il12a; OS Peromyscus maniculatus (Deer mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Cricetidae; Neotominae; Peromyscus. OX NCBI_TaxID=10042; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=14720307; DOI=10.1186/1471-2172-5-1; RA Schountz T., Green R., Davenport B., Buniger A., Richens T., RA Root J.J., Davidson F., Calisher C.H., Beaty B.J.; RT "Cloning and characterization of deer mouse (Peromyscus maniculatus) RT cytokine and chemokine cDNAs."; RL BMC Immunol. 5:1-1(2004). CC -!- FUNCTION: Cytokine that can act as a growth factor for activated T CC and NK cells, enhance the lytic activity of NK/lymphokine- CC activated Killer cells, and stimulate the production of IFN-gamma CC by resting PBMC (By similarity). CC -!- SUBUNIT: Heterodimer with IL12B; disulfide-linked. The heterodimer CC is known as interleukin IL-12 (By similarity). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY247763; AAP04422.1; -; mRNA. DR HSSP; P29459; 1F45. DR GO; GO:0005576; C:extracellular region; IEA:InterPro. DR GO; GO:0005143; F:interleukin-12 receptor binding; IEA:InterPro. DR GO; GO:0006955; P:immune response; IEA:InterPro. DR InterPro; IPR009079; 4_helix_cytokine. DR InterPro; IPR004281; IL12. DR Gene3D; G3DSA:1.20.120.250; IL12; 1. DR PANTHER; PTHR10523; IL12; 1. DR Pfam; PF03039; IL12; 1. FT NON_TER 1 1 FT NON_TER 61 61 SQ SEQUENCE 61 AA; 6975 MW; 43FF88BD8ED8746F CRC64; HLSLARATPV SRPAQCLDHS KNLLRTTKHM LEKARQTLRH YPCTPEDVDY EDITGEKTST L //