ID Q80UJ0_MOUSE Unreviewed; 347 AA. AC Q80UJ0; DT 01-JUN-2003, integrated into UniProtKB/TrEMBL. DT 16-AUG-2004, sequence version 2. DT 14-DEC-2022, entry version 141. DE RecName: Full=ELAV-like protein {ECO:0000256|RuleBase:RU361281}; GN Name=Elavl2 {ECO:0000313|EMBL:AAH46598.2, GN ECO:0000313|Ensembl:ENSMUSP00000102727.2, GN ECO:0000313|MGI:MGI:1100887}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; OC Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|EMBL:AAH46598.2}; RN [1] {ECO:0000313|EMBL:AAH46598.2} RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Olfactory epithelium {ECO:0000313|EMBL:AAH46598.2}; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., RA Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M., RA Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., RA Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., RA Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., RA Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., RA Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., RA Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., RA Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., RA Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., RA Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., RA Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., RA Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., RA Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., RA Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., RA Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., RA Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.; RT "The status, quality, and expansion of the NIH full-length cDNA project: RT the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). RN [2] {ECO:0000313|Ensembl:ENSMUSP00000102727.2, ECO:0000313|Proteomes:UP000000589} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000102727.2, RC ECO:0000313|Proteomes:UP000000589}; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., RA Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of the RT mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [3] {ECO:0000313|Ensembl:ENSMUSP00000102727.2} RP IDENTIFICATION. RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000102727.2}; RG Ensembl; RL Submitted (AUG-2022) to UniProtKB. CC -!- SIMILARITY: Belongs to the RRM elav family. CC {ECO:0000256|ARBA:ARBA00006266, ECO:0000256|RuleBase:RU361281}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC046598; AAH46598.2; -; mRNA. DR RefSeq; NP_034616.1; NM_010486.2. DR RefSeq; NP_997569.1; NM_207686.1. DR SMR; Q80UJ0; -. DR ProteomicsDB; 341143; -. DR Antibodypedia; 10496; 342 antibodies from 30 providers. DR DNASU; 15569; -. DR Ensembl; ENSMUST00000107110.8; ENSMUSP00000102727.2; ENSMUSG00000008489.19. DR GeneID; 15569; -. DR KEGG; mmu:15569; -. DR UCSC; uc008too.2; mouse. DR AGR; MGI:1100887; -. DR CTD; 1993; -. DR MGI; MGI:1100887; Elavl2. DR VEuPathDB; HostDB:ENSMUSG00000008489; -. DR GeneTree; ENSGT00940000156823; -. DR OrthoDB; 775799at2759; -. DR BioGRID-ORCS; 15569; 0 hits in 75 CRISPR screens. DR ChiTaRS; Elavl2; mouse. DR Proteomes; UP000000589; Chromosome 4. DR Bgee; ENSMUSG00000008489; Expressed in superior cervical ganglion and 215 other tissues. DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:InterPro. DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule. DR CDD; cd12650; RRM1_Hu; 1. DR CDD; cd12775; RRM2_HuB; 1. DR CDD; cd12654; RRM3_HuB; 1. DR Gene3D; 3.30.70.330; -; 3. DR InterPro; IPR006548; ELAD_HU_SF. DR InterPro; IPR034775; ELAV/Hu_RRM1. DR InterPro; IPR034999; HuB_RRM2. DR InterPro; IPR034914; HuB_RRM3. DR InterPro; IPR002343; Hud_Sxl_RNA. DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf. DR InterPro; IPR035979; RBD_domain_sf. DR InterPro; IPR000504; RRM_dom. DR Pfam; PF00076; RRM_1; 3. DR PRINTS; PR00961; HUDSXLRNA. DR SMART; SM00360; RRM; 3. DR SUPFAM; SSF54928; RNA-binding domain, RBD; 2. DR TIGRFAMs; TIGR01661; ELAV_HUD_SF; 1. DR PROSITE; PS50102; RRM; 3. PE 1: Evidence at protein level; KW Proteomics identification {ECO:0007829|MaxQB:Q80UJ0, KW ECO:0007829|PeptideAtlas:Q80UJ0}; KW Reference proteome {ECO:0000313|Proteomes:UP000000589}; KW Repeat {ECO:0000256|ARBA:ARBA00022737}; KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE- KW ProRule:PRU00176}. FT DOMAIN 39..117 FT /note="RRM" FT /evidence="ECO:0000259|PROSITE:PS50102" FT DOMAIN 125..205 FT /note="RRM" FT /evidence="ECO:0000259|PROSITE:PS50102" FT DOMAIN 264..342 FT /note="RRM" FT /evidence="ECO:0000259|PROSITE:PS50102" FT REGION 1..36 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" SQ SEQUENCE 347 AA; 38088 MW; 0BF259D5AF5E5FA2 CRC64; METQLSNGPT CNNTANGPTT VNNNCSSPVD SGNTEDSKTN LIVNYLPQNM TQEELKSLFG SIGEIESCKL VRDKITGQSL GYGFVNYIDP KDAEKAINTL NGLRLQTKTI KVSYARPSSA SIRDANLYVS GLPKTMTQKE LEQLFSQYGR IITSRILVDQ VTGISRGVGF IRFDKRIEAE EAIKGLNGQK PPGATEPITV KFANNPSQKT NQAILSQLYQ SPNRRYPGPL AQQAQRFSRF SPMTIDGMTS LAGINIPGHP GTGWCIFVYN LAPDADESIL WQMFGPFGAV TNVKVIRDFN TNKCKGFGFV TMTNYDEAAM AIASLNGYRL GDRVLQVSFK TNKTHKA //