ID Q80SV8 PRELIMINARY; PRT; 1013 AA. AC Q80SV8; DT 01-JUN-2003 (TrEMBLrel. 24, Created) DT 01-JUN-2003 (TrEMBLrel. 24, Last sequence update) DT 01-MAR-2004 (TrEMBLrel. 26, Last annotation update) DE NOD2. GN CARD15 OR NOD2. OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Mus. OX NCBI_TaxID=10090; RN [1] RP SEQUENCE FROM N.A. RC STRAIN=SM/J, NZW/LacJ, and AU/SsJ; RX MEDLINE=22563394; PubMed=12676561; RA Ogura Y., Saab L., Chen F.F., Benito A., Inohara N., Nunez G.; RT "Genetic variation and activity of mouse Nod2, a susceptibility gene RT for Crohn's disease."; RL Genomics 81:369-377(2003). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY160388; AAN57791.1; -. DR EMBL; AY160380; AAN57791.1; JOINED. DR EMBL; AY160381; AAN57791.1; JOINED. DR EMBL; AY160382; AAN57791.1; JOINED. DR EMBL; AY160383; AAN57791.1; JOINED. DR EMBL; AY160384; AAN57791.1; JOINED. DR EMBL; AY160385; AAN57791.1; JOINED. DR EMBL; AY160386; AAN57791.1; JOINED. DR EMBL; AY160387; AAN57791.1; JOINED. DR EMBL; AY160468; AAN59994.1; -. DR EMBL; AY160460; AAN59994.1; JOINED. DR EMBL; AY160461; AAN59994.1; JOINED. DR EMBL; AY160462; AAN59994.1; JOINED. DR EMBL; AY160463; AAN59994.1; JOINED. DR EMBL; AY160464; AAN59994.1; JOINED. DR EMBL; AY160465; AAN59994.1; JOINED. DR EMBL; AY160466; AAN59994.1; JOINED. DR EMBL; AY160467; AAN59994.1; JOINED. DR EMBL; AY160638; AAN63037.1; -. DR EMBL; AY160630; AAN63037.1; JOINED. DR EMBL; AY160631; AAN63037.1; JOINED. DR EMBL; AY160632; AAN63037.1; JOINED. DR EMBL; AY160633; AAN63037.1; JOINED. DR EMBL; AY160634; AAN63037.1; JOINED. DR EMBL; AY160635; AAN63037.1; JOINED. DR EMBL; AY160636; AAN63037.1; JOINED. DR EMBL; AY160637; AAN63037.1; JOINED. DR MGD; MGI:2429397; Card15. DR GO; GO:0005622; C:intracellular; IEA. DR GO; GO:0016329; F:apoptosis regulator activity; IEA. DR GO; GO:0006915; P:apoptosis; IEA. DR InterPro; IPR001315; CARD. DR InterPro; IPR001611; LRR. DR InterPro; IPR007091; LRR_RNinh. DR InterPro; IPR003590; LRR_RNinh_sub. DR InterPro; IPR007111; NACHT_NTPase. DR InterPro; IPR001130; TatD_DNase. DR Pfam; PF00560; LRR; 1. DR Pfam; PF05729; NACHT; 1. DR SMART; SM00368; LRR_RI; 8. DR PROSITE; PS50209; CARD; 2. DR PROSITE; PS50837; NACHT; 1. DR PROSITE; PS01137; TATD_1; UNKNOWN_1. SQ SEQUENCE 1013 AA; 112803 MW; 9D41BA39FAC1905E CRC64; MCSQEEFQAQ RSQLVALLIS GSLEGFESIL DWLLSWDVLS REDYEGLSLP GQPLSHSARR LLDTVWNKGV WGCQKLLEAV QEAQANSHTF ELHGSWDTHS VHPTRDLQSH RPAIVRRLYN HVEAMLELAR EGGFLSQYEC EEIRLPIFTS SQRARRLLDL AAVKANGLAA FLLQHVRELP ALLPLPYEAA ECQKFISKLR TMVLAQSRFL STYDGSENLC LEDIYTENIL ELRTEVGTAG ALQKSPAILG LEDLFDTHGH LNRDADTILV VGEAGSGKST LLQRLHLLWA TGRSFQEFLF IFPFSCRQLQ CVAKPLSLRT LLFEHCCWPD VAQDDVFQFL LDHPDRVLLT FDGLDEFKFR FTDRERHCSP IDPTSVQTLL FNLLQGNLLK NACKVLTSRP DAVSALLRKF VRTECQLKGF SEEGIQLYLR KHHREPGVAD RLIQLIQATS ALHGLCHLPV FSWMVSRCHR ELLLQNRVFP TTSTDMYLLI LQHFLLHASP PDSSPFGLGP GLLQSRLSTL LHLGHLALRG LAMSCYVFSA QQLQAAQVDS DDISLGFLVR AQSSVPGSKA PLEFLHITFQ CFFAAFYLAV SADTSAASLK HLFSCGRLGS SLLGRLLPNL CIQGSRVKKG SEAALLQKAE PHNLQITAAF LAGLLSQQHR DLLAACQISE RVLLQRQARA RSCLAHSLRE HFHSIPPAVP GETKSMHAMP GFIWLIRSLY EMQEEQLAQE AVRRLDIGHL KLTFCRVGPA ECAALAFVLQ HLQRPVALQL DYNSVGDVGV EQLRPCLGVC TALYLRDNNI SDRGARTLVE CALRCEQLQK LALFNNKLTD ACACSMAKLL AHKQNFLSLR VGNNHITAAG AEVLAQGLKS NTSLKFLGFW GNSVGDKGTQ ALAEVVADHQ NLKWLSLVGN NIGSMGAQAL ALMLEKNKSL EELCLEENHI CDEGVYSLAE GLKRNSTLKF LKLSNNGITY RGAEALLQAL SRNSAILEVW LRGNTFSLEE IQTLSSRDAR LLL //