ID A9A1B_DANRE Reviewed; 518 AA. AC Q802W2; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 01-JUN-2003, sequence version 1. DT 02-OCT-2007, entry version 27. DE Aldehyde dehydrogenase family 9 member A1-B (EC 1.2.1.3). GN Name=aldh9a1b; Synonyms=aldh9a1; OS Danio rerio (Zebrafish) (Brachydanio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. OX NCBI_TaxID=7955; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=AB; RG NIH - Zebrafish Gene Collection (ZGC) project; RL Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: An aldehyde + NAD(+) + H(2)O = an acid + NADH. CC -!- SUBUNIT: Homotetramer (By similarity). CC -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity). CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC047176; AAH47176.1; -; mRNA. DR RefSeq; NP_958916.1; -. DR UniGene; Dr.23802; -. DR HSSP; P56533; 1A4S. DR Ensembl; ENSDARG00000037061; Danio rerio. DR GeneID; 399481; -. DR ZFIN; ZDB-GENE-040120-5; aldh9a1. DR ArrayExpress; Q802W2; -. DR InterPro; IPR002086; Ald_DH. DR InterPro; IPR015590; Aldehyde_dehyd. DR InterPro; IPR012303; NAD-dep_ald-DH. DR PANTHER; PTHR11699; Aldehyde_dehyd; 1. DR Pfam; PF00171; Aldedh; 1. DR PIRSF; PIRSF000147; DHA; 1. DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1. DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1. PE 2: Evidence at transcript level; KW Cytoplasm; NAD; Oxidoreductase. FT CHAIN 1 518 Aldehyde dehydrogenase family 9 member FT A1-B. FT /FTId=PRO_0000300625. FT NP_BIND 256 261 NAD (By similarity). FT ACT_SITE 278 278 Potential. FT ACT_SITE 312 312 Potential. SQ SEQUENCE 518 AA; 56387 MW; 8F5077B7F7F802A4 CRC64; MALMRCLLPP GFYRTLYNPG TRCASSGTLQ IKDPLNFWCG ARVDLKDVKT KSEPVFEPAT GRVLCRLQTC GSAEVDAAVR NASVAFTVWR KLSGMERARV MMEAARLIEK RREEIAEMEV INNGKSITEA RLDVDSARLC IEYFAGQATT LSGQHVQLPG GSFAYTHREP FGVCVGIGAW NYPFQIAAWK SAPAIACGNS MVFKPSPLTP VTAVLLAEIY RQAGAPDGLF NVVQGGQETG SLLCLHPSVE KVSFTGSVPT GKKIMEMASR GVKAVTLELG GKSPLIIFED TDLENAVRGA LMANFLSQGQ VCSNGTRVFV QSSIVPQFLK EVVRRTKAIS IRDPLLDETR MGALVSKAHL DKVLRYVEQA KNEGAQVLCG GEPFSPADPK LKDGYYMTPC VLDSCTDDMT CVKEEIFGPV MSVLTFDTED EVLRRANDSD LGLAAGVFTK DVKRAHRVIE NLQAGSCFIN NYNITPVEVP FGGFKASGIG RENGQVTIEF YSQLKTVVVE MGDVDSLF //