ID P2C38_ORYSJ Reviewed; 460 AA. AC Q7XW27; DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot. DT 01-MAR-2004, sequence version 2. DT 17-FEB-2016, entry version 78. DE RecName: Full=Probable protein phosphatase 2C 38; DE Short=OsPP2C38; DE EC=3.1.3.16; GN OrderedLocusNames=Os04g0321800, LOC_Os04g25570; GN ORFNames=OSJNBb0062H02.4; OS Oryza sativa subsp. japonica (Rice). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BOP clade; OC Oryzoideae; Oryzeae; Oryzinae; Oryza. OX NCBI_TaxID=39947; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Nipponbare; RX PubMed=12447439; DOI=10.1038/nature01183; RA Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., RA Liu Y., Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., RA Weng Q., Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., RA Liu X., Lu T., Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., RA Wu M., Zhang R., Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., RA Cai Z., Ren S., Lv G., Gu W., Zhu G., Tu Y., Jia J., Zhang Y., RA Chen J., Kang H., Chen X., Shao C., Sun Y., Hu Q., Zhang X., Zhang W., RA Wang L., Ding C., Sheng H., Gu J., Chen S., Ni L., Zhu F., Chen W., RA Lan L., Lai Y., Cheng Z., Gu M., Jiang J., Li J., Hong G., Xue Y., RA Han B.; RT "Sequence and analysis of rice chromosome 4."; RL Nature 420:316-320(2002). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Nipponbare; RX PubMed=16100779; DOI=10.1038/nature03895; RG International rice genome sequencing project (IRGSP); RT "The map-based sequence of the rice genome."; RL Nature 436:793-800(2005). RN [3] RP GENOME REANNOTATION. RC STRAIN=cv. Nipponbare; RX PubMed=18089549; DOI=10.1093/nar/gkm978; RG The rice annotation project (RAP); RT "The rice annotation project database (RAP-DB): 2008 update."; RL Nucleic Acids Res. 36:D1028-D1033(2008). RN [4] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=cv. Nipponbare; RX PubMed=12869764; DOI=10.1126/science.1081288; RG The rice full-length cDNA consortium; RT "Collection, mapping, and annotation of over 28,000 cDNA clones from RT japonica rice."; RL Science 301:376-379(2003). RN [5] RP GENE FAMILY, AND NOMENCLATURE. RX PubMed=19021904; DOI=10.1186/1471-2164-9-550; RA Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., RA Zhong Y.; RT "Genome-wide and expression analysis of protein phosphatase 2C in rice RT and Arabidopsis."; RL BMC Genomics 9:550-550(2008). CC -!- CATALYTIC ACTIVITY: [a protein]-serine/threonine phosphate + H(2)O CC = [a protein]-serine/threonine + phosphate. CC -!- COFACTOR: CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; CC Note=Binds 2 magnesium or manganese ions per subunit. CC {ECO:0000250}; CC -!- SIMILARITY: Belongs to the PP2C family. {ECO:0000305}. CC -!- SIMILARITY: Contains 1 PPM-type phosphatase domain. CC {ECO:0000255|PROSITE-ProRule:PRU01082}. CC -!- SEQUENCE CAUTION: CC Sequence=AK071295; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305}; CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AL663005; CAD40291.2; -; Genomic_DNA. DR EMBL; AP008210; BAF14379.1; -; Genomic_DNA. DR EMBL; AK071295; -; NOT_ANNOTATED_CDS; mRNA. DR RefSeq; NP_001052465.1; NM_001059000.1. DR UniGene; Os.52757; -. DR ProteinModelPortal; Q7XW27; -. DR STRING; 39947.LOC_Os04g25570.1; -. DR PaxDb; Q7XW27; -. DR EnsemblPlants; OS04T0321800-02; OS04T0321800-02; OS04G0321800. DR GeneID; 4335480; -. DR Gramene; OS04T0321800-02; OS04T0321800-02; OS04G0321800. DR KEGG; osa:4335480; -. DR eggNOG; KOG0698; Eukaryota. DR eggNOG; COG0631; LUCA. DR InParanoid; Q7XW27; -. DR OMA; NMPGLAM; -. DR Proteomes; UP000000763; Chromosome 4. DR Genevisible; Q7XW27; OS. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro. DR Gene3D; 3.60.40.10; -; 1. DR InterPro; IPR015655; PP2C. DR InterPro; IPR001932; PPM-type_phosphatase_dom. DR PANTHER; PTHR13832; PTHR13832; 2. DR Pfam; PF00481; PP2C; 1. DR SMART; SM00331; PP2C_SIG; 1. DR SMART; SM00332; PP2Cc; 1. DR SUPFAM; SSF81606; SSF81606; 2. DR PROSITE; PS51746; PPM_2; 1. PE 2: Evidence at transcript level; KW Complete proteome; Hydrolase; Magnesium; Manganese; Metal-binding; KW Protein phosphatase; Reference proteome. FT CHAIN 1 460 Probable protein phosphatase 2C 38. FT /FTId=PRO_0000363285. FT DOMAIN 118 432 PPM-type phosphatase. FT {ECO:0000255|PROSITE-ProRule:PRU01082}. FT COMPBIAS 45 51 Poly-Gly. FT COMPBIAS 86 90 Poly-Arg. FT COMPBIAS 93 99 Poly-Ser. FT METAL 154 154 Manganese 1. {ECO:0000250}. FT METAL 154 154 Manganese 2. {ECO:0000250}. FT METAL 155 155 Manganese 1; via carbonyl oxygen. FT {ECO:0000250}. FT METAL 377 377 Manganese 2. {ECO:0000250}. FT METAL 423 423 Manganese 2. {ECO:0000250}. SQ SEQUENCE 460 AA; 49687 MW; 40B7D9A4A8E6820C CRC64; MVAVTGGRPP GLQDAPGAPP PAPAAEAVPS RPLARDATYG GRVYGGVGGG GCCLEFLDCV LRAMGVATPA EIMPPADFRW AARPMRRRRR GGSSSSSSSP RDREPRDGRI AANGASAAAS LYTMRGNKGV NQDAMLVWEN FCSKEDTIFC GVFDGHGPYG HLVSKRVRDL LPIKLSANLG RDGHKETSTN IVTSSMTEGG GTERMDRDTE TPLGTEENGD YPEMFAALRT SLLRAFYVMD RDLKFHKTID SVFSGTTAVT VIKQGHDLLI GNLGDSRAVL GTRDEYDQFF AVQLTVDLKP TIPSEAARIR ERSGRIFSLP DEPDVARVWL PKYNMPGLAM ARAFGDFCLK DYGLISMPDV SYHRITEKDE FVVLATDGVW DVLSNSEVVS IVSQAKSEAS AARFVVESAQ RAWRTRFPTS KIDDCAVVCL FLNTDARNKP PGSGIKDLAN AIELGGGNLS //