ID Q7TSV8_MOUSE Unreviewed; 275 AA. AC Q7TSV8; DT 01-OCT-2003, integrated into UniProtKB/TrEMBL. DT 01-OCT-2003, sequence version 1. DT 07-JAN-2015, entry version 54. DE SubName: Full=Ace protein {ECO:0000313|EMBL:AAH52531.1}; DE Flags: Fragment; GN Name=Ace {ECO:0000313|EMBL:AAH52531.1, ECO:0000313|MGI:MGI:87874}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|EMBL:AAH52531.1}; RN [1] {ECO:0000313|EMBL:AAH52531.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=Czech II {ECO:0000313|EMBL:AAH52531.1}; RC TISSUE=Lung {ECO:0000313|EMBL:AAH52531.1}; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., RA Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., RA Feolo M., Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., RA Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., RA Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., RA Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., RA Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., RA Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., RA Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., RA Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., RA Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., RA Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., RA Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., RA Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., RA Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., RA Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., RA Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., RA Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., RA Makowski K.A., Bosak S., Malek J.; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). CC -!- COFACTOR: CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105; CC Evidence={ECO:0000256|RuleBase:RU361144}; CC Note=Binds 1 zinc ion per subunit. CC {ECO:0000256|RuleBase:RU361144}; CC -!- COFACTOR: CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105; CC Evidence={ECO:0000256|RuleBase:RU361144}; CC Note=Binds 2 Zn(2+) ions per subunit. CC {ECO:0000256|RuleBase:RU361144}; CC -!- SIMILARITY: Belongs to the peptidase M2 family. CC {ECO:0000256|RuleBase:RU361144}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC052531; AAH52531.1; -; mRNA. DR UniGene; Mm.754; -. DR ProteinModelPortal; Q7TSV8; -. DR MGI; MGI:87874; Ace. DR HOVERGEN; HBG103676; -. DR Genevestigator; Q7TSV8; -. DR GO; GO:0016020; C:membrane; IEA:InterPro. DR GO; GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW. DR GO; GO:0008233; F:peptidase activity; IMP:MGI. DR GO; GO:0008241; F:peptidyl-dipeptidase activity; IEA:InterPro. DR GO; GO:0060047; P:heart contraction; IMP:MGI. DR GO; GO:0001822; P:kidney development; IMP:MGI. DR GO; GO:0002446; P:neutrophil mediated immunity; IMP:MGI. DR GO; GO:0003084; P:positive regulation of systemic arterial blood pressure; IMP:MGI. DR GO; GO:0007283; P:spermatogenesis; IMP:MGI. DR InterPro; IPR001548; Peptidase_M2. DR PANTHER; PTHR10514; PTHR10514; 1. DR Pfam; PF01401; Peptidase_M2; 1. DR PRINTS; PR00791; PEPDIPTASEA. PE 2: Evidence at transcript level; KW Carboxypeptidase {ECO:0000256|RuleBase:RU361144}; KW Glycoprotein {ECO:0000256|RuleBase:RU361144}; KW Hydrolase {ECO:0000256|RuleBase:RU361144}; KW Metal-binding {ECO:0000256|RuleBase:RU361144}; KW Metalloprotease {ECO:0000256|RuleBase:RU361144}; KW Protease {ECO:0000256|RuleBase:RU361144}; KW Zinc {ECO:0000256|RuleBase:RU361144}. FT NON_TER 1 1 {ECO:0000313|EMBL:AAH52531.1}. SQ SEQUENCE 275 AA; 31580 MW; AEB59A8A27881999 CRC64; GTRNLLSTEG SGYEFDINFL MKMALDKIAF IPFSYLIDQW RWRVFDGSIT KENYNQEWWS LRLNYQGLCP PVPRSQGDFD PGSKFHVPAN VPYVRYFVSF IIQFQFHEAL CRAAGHTGPL HKCDIYQSKE AGKLLADAMK LGYSKPWPEA MKLITGQPNM SASAMMNYFK PLTEWLVTEN RRHGETLGWP EYNWAPNTAR AEGSTAESNR VNFLGLYLEP QQARVGQWVL LFLGVALLVA TVGLAHRLYN IRNHHSLRRP HRGPQFGSEV ELRHS //