ID Q7TMV8_MOUSE Unreviewed; 380 AA. AC Q7TMV8; DT 01-OCT-2003, integrated into UniProtKB/TrEMBL. DT 01-OCT-2003, sequence version 1. DT 08-JUN-2016, entry version 66. DE SubName: Full=Mpa2l protein {ECO:0000313|EMBL:AAH52867.1}; DE Flags: Fragment; GN Name=Gbp6 {ECO:0000313|MGI:MGI:2140937}; GN Synonyms=Mpa2l {ECO:0000313|EMBL:AAH52867.1}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|EMBL:AAH52867.1}; RN [1] {ECO:0000313|EMBL:AAH52867.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=C57BL/6NCr {ECO:0000313|EMBL:AAH52867.1}; RC TISSUE=Hematopoietic Stem Cell {ECO:0000313|EMBL:AAH52867.1}; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., RA Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., RA Feolo M., Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., RA Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., RA Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., RA Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., RA Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., RA Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., RA Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., RA Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., RA Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., RA Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., RA Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., RA Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., RA Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., RA Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., RA Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., RA Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., RA Makowski K.A., Bosak S., Malek J.; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC052867; AAH52867.1; -; mRNA. DR UniGene; Mm.491210; -. DR ProteinModelPortal; Q7TMV8; -. DR STRING; 10090.ENSMUSP00000062528; -. DR PaxDb; Q7TMV8; -. DR MGI; MGI:2140937; Gbp6. DR eggNOG; KOG2037; Eukaryota. DR eggNOG; ENOG410XR6Z; LUCA. DR HOVERGEN; HBG001979; -. DR GO; GO:0031410; C:cytoplasmic vesicle; IDA:MGI. DR GO; GO:0070062; C:extracellular exosome; ISO:MGI. DR GO; GO:0020005; C:symbiont-containing vacuole membrane; IDA:MGI. DR GO; GO:0005525; F:GTP binding; IEA:InterPro. DR GO; GO:0003924; F:GTPase activity; IEA:InterPro. DR GO; GO:0044406; P:adhesion of symbiont to host; IDA:MGI. DR GO; GO:0035458; P:cellular response to interferon-beta; IDA:MGI. DR GO; GO:0071346; P:cellular response to interferon-gamma; IDA:MGI. DR GO; GO:0071222; P:cellular response to lipopolysaccharide; IDA:MGI. DR GO; GO:0050830; P:defense response to Gram-positive bacterium; IDA:MGI. DR GO; GO:0042832; P:defense response to protozoan; IDA:MGI. DR InterPro; IPR030386; G_GB1_RHD3_dom. DR InterPro; IPR003191; Guanylate-bd_C. DR InterPro; IPR015894; Guanylate-bd_N. DR Pfam; PF02263; GBP; 1. DR Pfam; PF02841; GBP_C; 1. DR SUPFAM; SSF48340; SSF48340; 1. DR PROSITE; PS51715; G_GB1_RHD3; 1. PE 2: Evidence at transcript level; KW Coiled coil {ECO:0000256|SAM:Coils}. FT DOMAIN 1 44 GB1/RHD3-type G (guanine nucleotide- FT binding). {ECO:0000259|PROSITE:PS51715}. FT COILED 253 309 {ECO:0000256|SAM:Coils}. FT COILED 326 360 {ECO:0000256|SAM:Coils}. FT NON_TER 1 1 {ECO:0000313|EMBL:AAH52867.1}. SQ SEQUENCE 380 AA; 44287 MW; 7799E5F13BFE1CA6 CRC64; RGNPRPTHDK ELLQKLDSIT EDQLDPKFQE VTKAFVSYIF TYAKIKTLKE GIKVTGNRLG ILVTTYVNAI NSGAVPCLDD AVTTLAQREN SVAVQKAADH YSEQMAQRLR LPTETLQELL DVHAACEKEA MAVFMEHSFK DENQQFLKKL VELIGENKEL FLSKNEEASN KYCQEELDRL SKDFMENIST FFVPCGHKLY MDKREKIEHD YWQVPRKGVK ASEVFQSFLQ SQAFIESSIL QADTALTAGE KAIAEERAQK VAAEKEQELL RQKQKEQQEH MEAQEKSHKE NLEQLRRKLE QEREQDIKDH DMMLKKLMKD QKAFLEEGFK KKAEEMNKEI QQLRDVIKDK KRNTDRIKEA LLNGFSTVLF HYLVRYLKHL //