ID Q7TMI9_MOUSE Unreviewed; 435 AA. AC Q7TMI9; DT 01-OCT-2003, integrated into UniProtKB/TrEMBL. DT 01-OCT-2003, sequence version 1. DT 03-JUL-2019, entry version 82. DE SubName: Full=Axin1 protein {ECO:0000313|EMBL:AAH55491.1}; DE Flags: Fragment; GN Name=Axin1 {ECO:0000313|EMBL:AAH55491.1, ECO:0000313|MGI:MGI:1096327}; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090 {ECO:0000313|EMBL:AAH55491.1}; RN [1] {ECO:0000313|EMBL:AAH55491.1} RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=FVB/N {ECO:0000313|EMBL:AAH55491.1}; RC TISSUE=Mammary tumor. C3 {ECO:0000313|EMBL:AAH55491.1}; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., RA Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., RA Feolo M., Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., RA Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., RA Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., RA Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., RA Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., RA Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., RA Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., RA Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., RA Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., RA Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., RA Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., RA Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., RA Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., RA Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., RA Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., RA Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., RA Makowski K.A., Bosak S., Malek J.; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC055491; AAH55491.1; -; mRNA. DR PeptideAtlas; Q7TMI9; -. DR MGI; MGI:1096327; Axin1. DR ChiTaRS; Axin1; mouse. DR GO; GO:0030877; C:beta-catenin destruction complex; IEA:InterPro. DR GO; GO:0008013; F:beta-catenin binding; IEA:InterPro. DR GO; GO:0046330; P:positive regulation of JNK cascade; IEA:InterPro. DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW. DR Gene3D; 3.10.20.380; -; 1. DR InterPro; IPR029797; AXIN1. DR InterPro; IPR014936; Axin_b-cat-bd. DR InterPro; IPR001158; DIX. DR InterPro; IPR038207; DIX_dom_sf. DR InterPro; IPR029071; Ubiquitin-like_domsf. DR PANTHER; PTHR46102:SF3; PTHR46102:SF3; 1. DR Pfam; PF08833; Axin_b-cat_bind; 1. DR Pfam; PF00778; DIX; 1. DR SMART; SM00021; DAX; 1. DR SUPFAM; SSF54236; SSF54236; 1. DR PROSITE; PS50841; DIX; 1. PE 2: Evidence at transcript level; KW Wnt signaling pathway {ECO:0000256|PROSITE-ProRule:PRU00069}. FT DOMAIN 353 435 DIX. {ECO:0000259|PROSITE:PS50841}. FT REGION 20 42 Disordered. {ECO:0000256|MobiDB-lite: FT Q7TMI9}. FT REGION 137 232 Disordered. {ECO:0000256|MobiDB-lite: FT Q7TMI9}. FT REGION 250 276 Disordered. {ECO:0000256|MobiDB-lite: FT Q7TMI9}. FT REGION 321 350 Disordered. {ECO:0000256|MobiDB-lite: FT Q7TMI9}. FT NON_TER 1 1 {ECO:0000313|EMBL:AAH55491.1}. SQ SEQUENCE 435 AA; 48456 MW; C8E468789A2A880C CRC64; IHRLEAVQRT REAEEKLEER LKRVRMEEEG EDGEMPSGPM ASHKLPSVPA WHHFPPRYVD MGCSGLRDAH EENPESILDE HVQRVMRTPG CQSPGPGHRS PDSGHVAKTA VLGGTASGHG KHVPKLGLKL DTAGLHHHRH VHHHVHHNSA RPKEQMEAEV ARRVQSSFSW GPETHGHAKP RSYSENAGTT LSAGDLAFGG KTSAPSKRNT KKAESGKNAN AEVPSTTEDA EKNQKIMQWI IEGEKEISRH RKAGHGSSGL RKQQAHESSR PLSIERPGAV HPWVSAQLRN SVQPSHLFIQ DPTMPPNPAP NPLTQLEEAR RRLEEEEKRA NKLPSKQRTK SQRKAGGGSA PPCDSIVVAY YFCGEPIPYR TLVRGRAVTL GQFKELLTKK GSYRYYFKKV SDEFDCGVVF EEVREDEAVL PVFEEKIIGK VEKVD //