ID Q7TMI9_MOUSE Unreviewed; 435 AA. AC Q7TMI9; DT 01-OCT-2003, integrated into UniProtKB/TrEMBL. DT 01-OCT-2003, sequence version 1. DT 22-JAN-2014, entry version 52. DE SubName: Full=Axin1 protein; DE Flags: Fragment; GN Name=Axin1; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=FVB/N; TISSUE=Mammary tumor. C3; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., RA Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., RA Feolo M., Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., RA Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., RA Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., RA Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., RA Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., RA Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., RA Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., RA Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., RA Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., RA Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., RA Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., RA Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., RA Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., RA Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., RA Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., RA Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., RA Makowski K.A., Bosak S., Malek J.; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BC055491; AAH55491.1; -; mRNA. DR UniGene; Mm.23684; -. DR STRING; 10090.ENSMUSP00000073974; -. DR MGI; MGI:1096327; Axin1. DR HOVERGEN; HBG004324; -. DR ArrayExpress; Q7TMI9; -. DR Bgee; Q7TMI9; -. DR Genevestigator; Q7TMI9; -. DR GO; GO:0030877; C:beta-catenin destruction complex; IDA:MGI. DR GO; GO:0005938; C:cell cortex; IDA:MGI. DR GO; GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:MGI. DR GO; GO:0005881; C:cytoplasmic microtubule; IDA:MGI. DR GO; GO:0005886; C:plasma membrane; IDA:MGI. DR GO; GO:0014069; C:postsynaptic density; IBA:RefGenome. DR GO; GO:0070016; F:armadillo repeat domain binding; IBA:RefGenome. DR GO; GO:0008013; F:beta-catenin binding; IMP:MGI. DR GO; GO:0005096; F:GTPase activator activity; IBA:RefGenome. DR GO; GO:0008022; F:protein C-terminus binding; IDA:MGI. DR GO; GO:0004871; F:signal transducer activity; IEA:InterPro. DR GO; GO:0007257; P:activation of JUN kinase activity; IBA:RefGenome. DR GO; GO:0048320; P:axial mesoderm formation; IMP:MGI. DR GO; GO:0060823; P:canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation; IBA:RefGenome. DR GO; GO:0008219; P:cell death; IBA:RefGenome. DR GO; GO:0071407; P:cellular response to organic cyclic compound; IBA:RefGenome. DR GO; GO:0031122; P:cytoplasmic microtubule organization; IGI:MGI. DR GO; GO:0007368; P:determination of left/right symmetry; IBA:RefGenome. DR GO; GO:0009950; P:dorsal/ventral axis specification; IDA:MGI. DR GO; GO:0048048; P:embryonic eye morphogenesis; IBA:RefGenome. DR GO; GO:0021797; P:forebrain anterior/posterior pattern specification; IBA:RefGenome. DR GO; GO:0071514; P:genetic imprinting; IMP:MGI. DR GO; GO:0001701; P:in utero embryonic development; IMP:MGI. DR GO; GO:0055001; P:muscle cell development; IBA:RefGenome. DR GO; GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:MGI. DR GO; GO:0045599; P:negative regulation of fat cell differentiation; IDA:MGI. DR GO; GO:0051248; P:negative regulation of protein metabolic process; IDA:MGI. DR GO; GO:0034244; P:negative regulation of transcription elongation from RNA polymerase II promoter; IDA:MGI. DR GO; GO:0006913; P:nucleocytoplasmic transport; IDA:MGI. DR GO; GO:0030910; P:olfactory placode formation; IBA:RefGenome. DR GO; GO:0001743; P:optic placode formation; IBA:RefGenome. DR GO; GO:0046330; P:positive regulation of JNK cascade; IMP:MGI. DR GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:MGI. DR GO; GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:MGI. DR GO; GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IDA:MGI. DR GO; GO:0036342; P:post-anal tail morphogenesis; IMP:MGI. DR GO; GO:0030163; P:protein catabolic process; IDA:MGI. DR GO; GO:0051260; P:protein homooligomerization; IDA:MGI. DR GO; GO:0000209; P:protein polyubiquitination; IDA:MGI. DR GO; GO:0035412; P:regulation of catenin import into nucleus; IDA:MGI. DR GO; GO:0007605; P:sensory perception of sound; IMP:MGI. DR GO; GO:0021881; P:Wnt receptor signaling pathway involved in forebrain neuron fate commitment; IBA:RefGenome. DR GO; GO:0090244; P:Wnt receptor signaling pathway involved in somitogenesis; IBA:RefGenome. DR InterPro; IPR014936; Axin_b-cat-bd. DR InterPro; IPR001158; DIX. DR Pfam; PF08833; Axin_b-cat_bind; 1. DR Pfam; PF00778; DIX; 1. DR SMART; SM00021; DAX; 1. DR PROSITE; PS50841; DIX; 1. PE 2: Evidence at transcript level; FT NON_TER 1 1 SQ SEQUENCE 435 AA; 48456 MW; C8E468789A2A880C CRC64; IHRLEAVQRT REAEEKLEER LKRVRMEEEG EDGEMPSGPM ASHKLPSVPA WHHFPPRYVD MGCSGLRDAH EENPESILDE HVQRVMRTPG CQSPGPGHRS PDSGHVAKTA VLGGTASGHG KHVPKLGLKL DTAGLHHHRH VHHHVHHNSA RPKEQMEAEV ARRVQSSFSW GPETHGHAKP RSYSENAGTT LSAGDLAFGG KTSAPSKRNT KKAESGKNAN AEVPSTTEDA EKNQKIMQWI IEGEKEISRH RKAGHGSSGL RKQQAHESSR PLSIERPGAV HPWVSAQLRN SVQPSHLFIQ DPTMPPNPAP NPLTQLEEAR RRLEEEEKRA NKLPSKQRTK SQRKAGGGSA PPCDSIVVAY YFCGEPIPYR TLVRGRAVTL GQFKELLTKK GSYRYYFKKV SDEFDCGVVF EEVREDEAVL PVFEEKIIGK VEKVD //