ID   Q7T1K2_DANRE            Unreviewed;       470 AA.
AC   Q7T1K2;
DT   01-OCT-2003, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2003, sequence version 1.
DT   16-MAY-2012, entry version 87.
DE   SubName: Full=TRAF4 protein;
DE   SubName: Full=Tnf receptor-associated factor 4a;
DE   SubName: Full=Uncharacterized protein;
GN   Name=traf4a; Synonyms=traf4;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=15749085; DOI=10.1016/j.modgep.2004.10.011;
RA   Kedinger V., Alpy F., Tomasetto C., Thisse C., Thisse B., Rio M.C.;
RT   "Spatial and temporal distribution of the traf4 genes during zebrafish
RT   development.";
RL   Gene Expr. Patterns 5:545-552(2005).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen;
RG   The Danio rerio Sequencing Project at the Sanger Institute;
RT   "The genomic sequence of Danio rerio.";
RL   Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen;
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- SIMILARITY: Contains 1 MATH domain.
CC   -!- SIMILARITY: Contains 1 RING-type zinc finger.
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DR   EMBL; CR848661; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CR855391; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC065969; AAH65969.1; -; mRNA.
DR   EMBL; AJ556548; CAD89005.1; -; mRNA.
DR   IPI; IPI00486500; -.
DR   RefSeq; NP_991325.1; NM_205762.1.
DR   UniGene; Dr.81750; -.
DR   HSSP; Q12933; 1CZY.
DR   SMR; Q7T1K2; 102-164, 190-248.
DR   Ensembl; ENSDART00000016024; ENSDARP00000013849; ENSDARG00000003963.
DR   GeneID; 404045; -.
DR   KEGG; dre:404045; -.
DR   CTD; 404045; -.
DR   ZFIN; ZDB-GENE-040308-1; traf4a.
DR   eggNOG; NOG321306; -.
DR   GeneTree; ENSGT00550000074359; -.
DR   HOGENOM; HOG000004841; -.
DR   HOVERGEN; HBG103438; -.
DR   InParanoid; Q7T1K2; -.
DR   KO; K09848; -.
DR   OMA; KESCGSA; -.
DR   OrthoDB; EOG4868C9; -.
DR   NextBio; 20817516; -.
DR   Bgee; Q7T1K2; -.
DR   GO; GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; G3DSA:3.90.890.10; SIAH-type; 1.
DR   Gene3D; G3DSA:2.60.210.10; TRAF-type; 1.
DR   Gene3D; G3DSA:3.30.40.10; Znf_RING/FYVE/PHD; 1.
DR   InterPro; IPR002083; MATH.
DR   InterPro; IPR013323; SIAH-type.
DR   InterPro; IPR012227; TNF_rcpt--assoc_TRAF.
DR   InterPro; IPR008974; TRAF-like.
DR   InterPro; IPR013322; TRAF-type.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   InterPro; IPR001293; Znf_TRAF.
DR   Pfam; PF00917; MATH; 1.
DR   PIRSF; PIRSF015614; TRAF; 1.
DR   SMART; SM00061; MATH; 1.
DR   SMART; SM00184; RING; 1.
DR   SUPFAM; SSF49599; Traf_like; 4.
DR   PROSITE; PS50144; MATH; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
DR   PROSITE; PS50145; ZF_TRAF; 3.
PE   2: Evidence at transcript level;
KW   Complete proteome; Metal-binding; Receptor; Reference proteome; Zinc;
KW   Zinc-finger.
SQ   SEQUENCE   470 AA;  54427 MW;  B4CEA2AE913363D3 CRC64;
     MPGFDYKFLE KPKRRFQCPL CSKAMREPVQ VSTCGHRFCD TCLQEFLSEG VFKCPEDQLP
     LDYAKIYPDP ELEQQILALP IRCIHSEEGC RWTGQMKQLQ SHFSTCAFNV IPCPNRCSVK
     LTRRDLPEHL QHDCPKRKVK CEFCGSEFTG EAYENHQGIC PQESVYCENK CGARMMRRLL
     SQHTMTECPK RTQPCKYCGK EFVYDTIQNH QYHCPRFPVQ CPNQCGTPNI AREDLANHVK
     ESCGSALVLC PFKEAGCKHR CPKMAIGRHL EESTKSHLTM MCSLVGRQRQ EILELRREME
     ELSVSHDGVL IWKLTDYSRK LQEAKLRNNH EFFSPPFYTH RYGYKLQVSA FLNGNGSGEG
     SHLSIYIRVL PGEYDNLLEW PFSYKVTFSI LDQSDPSLSK PQHITETFNP DPNWKNFQKP
     CSSRNSLDES TLGFGYPKFI SHEEIKKRNY IRDNSIFLKA SIEIPQKIMA
//