ID TM111_DANRE Reviewed; 261 AA. AC Q7SXW4; Q5IFI3; DT 19-JUL-2005, integrated into UniProtKB/Swiss-Prot. DT 01-OCT-2003, sequence version 1. DT 05-OCT-2010, entry version 54. DE RecName: Full=Transmembrane protein 111; DE AltName: Full=Protein pob; GN Name=tmem111; Synonyms=pob; ORFNames=zgc:63727; OS Danio rerio (Zebrafish) (Brachydanio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. OX NCBI_TaxID=7955; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY. RX PubMed=15716502; DOI=10.1534/genetics.104.036434; RA Taylor M.R., Kikkawa S., Diez-Juan A., Ramamurthy V., Kawakami K., RA Carmeliet P., Brockerhoff S.E.; RT "The zebrafish pob gene encodes a novel protein required for survival RT of red cone photoreceptor cells."; RL Genetics 170:263-273(2005). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Kidney marrow; RX PubMed=15520368; DOI=10.1073/pnas.0407241101; RA Song H.-D., Sun X.-J., Deng M., Zhang G.-W., Zhou Y., Wu X.-Y., RA Sheng Y., Chen Y., Ruan Z., Jiang C.-L., Fan H.-Y., Zon L.I., RA Kanki J.P., Liu T.X., Look A.T., Chen Z.; RT "Hematopoietic gene expression profile in zebrafish kidney marrow."; RL Proc. Natl. Acad. Sci. U.S.A. 101:16240-16245(2004). RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC STRAIN=AB; RG NIH - Zebrafish Gene Collection (ZGC) project; RL Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein CC (Potential). CC -!- TISSUE SPECIFICITY: Localized to the inner segment and synapse in CC photoreceptor cells. CC -!- SIMILARITY: Belongs to the UPF0347 (TMEM111) family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AY745978; AAW19648.1; -; mRNA. DR EMBL; AY398377; AAQ97810.1; -; mRNA. DR EMBL; BC055222; AAH55222.1; -; mRNA. DR IPI; IPI00512587; -. DR RefSeq; NP_998670.1; -. DR UniGene; Dr.80620; -. DR Ensembl; ENSDART00000025441; ENSDARP00000009691; ENSDARG00000020607. DR GeneID; 406826; -. DR KEGG; dre:406826; -. DR CTD; 406826; -. DR ZFIN; ZDB-GENE-040426-2904; pob. DR eggNOG; fiNOG09286; -. DR HOGENOM; HBG626693; -. DR HOVERGEN; HBG056099; -. DR InParanoid; Q7SXW4; -. DR OMA; QMSGAAM; -. DR OrthoDB; EOG9WDGXC; -. DR PhylomeDB; Q7SXW4; -. DR ArrayExpress; Q7SXW4; -. DR Bgee; Q7SXW4; -. DR GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. DR GO; GO:0030140; C:trans-Golgi network transport vesicle; IDA:ZFIN. DR GO; GO:0045494; P:photoreceptor cell maintenance; IMP:ZFIN. DR GO; GO:0060041; P:retina development in camera-type eye; IMP:ZFIN. DR InterPro; IPR002809; DUF106_TM. DR InterPro; IPR008568; UCP010045_TM_euk. DR PANTHER; PTHR13116; DUF850_TM_euk; 1. DR Pfam; PF01956; DUF106; 1. DR PIRSF; PIRSF010045; DUF850_TM_euk; 1. PE 2: Evidence at transcript level; KW Membrane; Transmembrane; Transmembrane helix. FT CHAIN 1 261 Transmembrane protein 111. FT /FTId=PRO_0000211410. FT TRANSMEM 14 34 Helical; (Potential). FT TRANSMEM 118 138 Helical; (Potential). FT CONFLICT 25 25 F -> I (in Ref. 1; AAW19648). SQ SEQUENCE 261 AA; 29792 MW; EC717145BD15EEBC CRC64; MAEPELLLDS NIRLWVVLPI VFITFLVGVI RHYVSILLQS DKKLTLEQVS DSQVLIRSRV LRENGKYIPK QSFLMRKFYF NNQEDGFFKK TKRKVVPPSP MTDPSMLTDM MKGNVTNVLP MILIGGWINW TFSGFVTTKV PFPLTLRFKP MLQQGIELLS LDASWVSSAS WYFLNVFGLR SMYSLILGQD NGADQSRIMQ EQMSGAAMAM PADTNKAFKA EWEALELTDH QWALENVEED LMSKDLDLSG MFSKDLPTGI F //