ID RSM28_NEUCR Reviewed; 414 AA. AC Q7SG49; DT 13-SEP-2023, integrated into UniProtKB/Swiss-Prot. DT 15-DEC-2003, sequence version 1. DT 13-SEP-2023, entry version 64. DE RecName: Full=Small ribosomal subunit protein mS46 {ECO:0000303|PubMed:33056988}; GN Name=rsm28; ORFNames=NCU07493; OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / OS FGSC 987). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes; OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora. OX NCBI_TaxID=367110; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987; RX PubMed=12712197; DOI=10.1038/nature01554; RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., RA Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B., RA Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., RA Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M., RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U., RA Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D., RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S., RA Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D., RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S., RA Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A., RA DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R., RA Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R., RA Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., RA Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.; RT "The genome sequence of the filamentous fungus Neurospora crassa."; RL Nature 422:859-868(2003). RN [2] {ECO:0007744|PDB:6YW5, ECO:0007744|PDB:6YWX} RP STRUCTURE BY ELECTRON MICROSCOPY (2.85 ANGSTROMS). RX PubMed=33056988; DOI=10.1038/s41467-020-18830-w; RA Itoh Y., Naschberger A., Mortezaei N., Herrmann J.M., Amunts A.; RT "Analysis of translating mitoribosome reveals functional characteristics of RT translation in mitochondria of fungi."; RL Nat. Commun. 11:5187-5187(2020). CC -!- FUNCTION: Component of the mitochondrial ribosome (mitoribosome), a CC dedicated translation machinery responsible for the synthesis of CC mitochondrial genome-encoded proteins, including at least some of the CC essential transmembrane subunits of the mitochondrial respiratory CC chain. The mitoribosomes are attached to the mitochondrial inner CC membrane and translation products are cotranslationally integrated into CC the membrane. {ECO:0000305|PubMed:33056988}. CC -!- SUBUNIT: Component of the mitochondrial small ribosomal subunit (mt- CC SSU). Mature N.crassa 74S mitochondrial ribosomes consist of a small CC (37S) and a large (54S) subunit. The 37S small subunit contains a 16S CC ribosomal RNA (16S mt-rRNA) and 32 different proteins. The 54S large CC subunit contains a 23S rRNA (23S mt-rRNA) and 42 different proteins. CC {ECO:0000269|PubMed:33056988}. CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:33056988}. CC -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein CC mS46 family. {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CM002236; EAA35804.1; -; Genomic_DNA. DR RefSeq; XP_965040.1; XM_959947.3. DR PDB; 6YW5; EM; 2.85 A; 77=1-414. DR PDB; 6YWX; EM; 3.10 A; 77=1-414. DR PDBsum; 6YW5; -. DR PDBsum; 6YWX; -. DR AlphaFoldDB; Q7SG49; -. DR SMR; Q7SG49; -. DR STRING; 5141.EFNCRP00000007416; -. DR EnsemblFungi; EAA35804; EAA35804; NCU07493. DR GeneID; 3881189; -. DR KEGG; ncr:NCU07493; -. DR VEuPathDB; FungiDB:NCU07493; -. DR HOGENOM; CLU_053748_0_0_1; -. DR InParanoid; Q7SG49; -. DR OMA; QHETPKF; -. DR OrthoDB; 1778977at2759; -. DR Proteomes; UP000001805; Chromosome 1, Linkage Group I. PE 1: Evidence at protein level; KW 3D-structure; Mitochondrion; Reference proteome. FT CHAIN 1..414 FT /note="Small ribosomal subunit protein mS46" FT /id="PRO_0000458565" SQ SEQUENCE 414 AA; 43046 MW; 272753C6EB5BC3DF CRC64; MNRQVVTSTL GRRGVASTIL NAQQQQRPFS STTTRCAAED DSKKPAAAPS TPRAAAPGPI SASRQKSEAA VGKLTQLRGS FTSLTNDNSF HKTLPAGARD ARRLAAAPIA GKGAGAGAVA PLGGGGGASG APKVINVRSL KGTLGSRGSN NIPGAVAPGA ALRPRFAAGP GAAAGRPRFG AAASPGAGPT GAARRPPFGA RRARPAGDKK RSGGSGDKRP RGDDYDAPPT EEEKAFLRGL EQGKVTEYVP KLTPDTLLGY GPPVATDAAL GKVESAMRTM RILGGGLPFN DQSGVTSDPT AIKHRYVHEK KPVFFSSVEE KEWVRESLDK FAVSEGPEKK TKQKILETSV LGKYEEPKYV ESLTETVKMV EKYQGGTFSY APSDADKFNK KLNQLLAAGL PRAAPAPAQA QKKA //