ID   RM27_NEUCR              Reviewed;         103 AA.
AC   Q7S5W0;
DT   13-SEP-2023, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   08-NOV-2023, entry version 77.
DE   RecName: Full=Large ribosomal subunit protein mL41 {ECO:0000303|PubMed:33056988};
GN   Name=mrpl27; ORFNames=NCU07057;
OS   Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 /
OS   FGSC 987).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=367110;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987;
RX   PubMed=12712197; DOI=10.1038/nature01554;
RA   Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D.,
RA   Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B.,
RA   Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M.,
RA   Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M.,
RA   Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U.,
RA   Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D.,
RA   Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S.,
RA   Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D.,
RA   Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S.,
RA   Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A.,
RA   DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R.,
RA   Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R.,
RA   Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I.,
RA   Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.;
RT   "The genome sequence of the filamentous fungus Neurospora crassa.";
RL   Nature 422:859-868(2003).
RN   [2] {ECO:0007744|PDB:6YWS, ECO:0007744|PDB:6YWV}
RP   STRUCTURE BY ELECTRON MICROSCOPY (2.74 ANGSTROMS).
RX   PubMed=33056988; DOI=10.1038/s41467-020-18830-w;
RA   Itoh Y., Naschberger A., Mortezaei N., Herrmann J.M., Amunts A.;
RT   "Analysis of translating mitoribosome reveals functional characteristics of
RT   translation in mitochondria of fungi.";
RL   Nat. Commun. 11:5187-5187(2020).
CC   -!- FUNCTION: Component of the mitochondrial ribosome (mitoribosome), a
CC       dedicated translation machinery responsible for the synthesis of
CC       mitochondrial genome-encoded proteins, including at least some of the
CC       essential transmembrane subunits of the mitochondrial respiratory
CC       chain. The mitoribosomes are attached to the mitochondrial inner
CC       membrane and translation products are cotranslationally integrated into
CC       the membrane. {ECO:0000305|PubMed:33056988}.
CC   -!- SUBUNIT: Component of the mitochondrial large ribosomal subunit (mt-
CC       LSU). Mature N.crassa 74S mitochondrial ribosomes consist of a small
CC       (37S) and a large (54S) subunit. The 37S small subunit contains a 16S
CC       ribosomal RNA (16S mt-rRNA) and 32 different proteins. The 54S large
CC       subunit contains a 23S rRNA (23S mt-rRNA) and 42 different proteins.
CC       {ECO:0000269|PubMed:33056988}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:33056988}.
CC   -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC       mL41 family. {ECO:0000305}.
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DR   EMBL; CM002241; EAA30910.1; -; Genomic_DNA.
DR   RefSeq; XP_960146.1; XM_955053.2.
DR   PDB; 6YWS; EM; 2.74 A; 3=1-103.
DR   PDB; 6YWV; EM; 3.03 A; 3=1-103.
DR   PDB; 6YWX; EM; 3.10 A; 3=1-103.
DR   PDBsum; 6YWS; -.
DR   PDBsum; 6YWV; -.
DR   PDBsum; 6YWX; -.
DR   AlphaFoldDB; Q7S5W0; -.
DR   SMR; Q7S5W0; -.
DR   STRING; 5141.EFNCRP00000006955; -.
DR   PaxDb; 5141-EFNCRP00000006955; -.
DR   EnsemblFungi; EAA30910; EAA30910; NCU07057.
DR   GeneID; 3876293; -.
DR   KEGG; ncr:NCU07057; -.
DR   VEuPathDB; FungiDB:NCU07057; -.
DR   HOGENOM; CLU_131055_3_0_1; -.
DR   InParanoid; Q7S5W0; -.
DR   OMA; TTKQGPH; -.
DR   OrthoDB; 275237at2759; -.
DR   Proteomes; UP000001805; Chromosome 5, Linkage Group VI.
DR   GO; GO:0005762; C:mitochondrial large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; IBA:GO_Central.
DR   InterPro; IPR019189; Ribosomal_mL41.
DR   PANTHER; PTHR21338:SF0; 39S RIBOSOMAL PROTEIN L41, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR21338; MITOCHONDRIAL RIBOSOMAL PROTEIN L41; 1.
DR   Pfam; PF09809; MRP-L27; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Mitochondrion; Reference proteome; Ribonucleoprotein;
KW   Ribosomal protein; Transit peptide.
FT   CHAIN           1..103
FT                   /note="Large ribosomal subunit protein mL41"
FT                   /id="PRO_0000458588"
SQ   SEQUENCE   103 AA;  11776 MW;  D59C7695C4760FB1 CRC64;
     MQPTRILQGL KYRKLRLTTK DVNKGFYKGN RTGSMGTHTS YGTYKIDYTK VRTYVCPDLT
     GFKLTPFVSK TIRPVHDQFP GDKLGPKNPA TYLARWKSEN GLD
//