ID RM27_NEUCR Reviewed; 103 AA. AC Q7S5W0; DT 13-SEP-2023, integrated into UniProtKB/Swiss-Prot. DT 15-DEC-2003, sequence version 1. DT 13-SEP-2023, entry version 76. DE RecName: Full=Large ribosomal subunit protein mL41 {ECO:0000303|PubMed:33056988}; GN Name=mrpl27; ORFNames=NCU07057; OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / OS FGSC 987). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes; OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora. OX NCBI_TaxID=367110; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987; RX PubMed=12712197; DOI=10.1038/nature01554; RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., RA Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B., RA Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., RA Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M., RA Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U., RA Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D., RA Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S., RA Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D., RA Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S., RA Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A., RA DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R., RA Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R., RA Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., RA Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.; RT "The genome sequence of the filamentous fungus Neurospora crassa."; RL Nature 422:859-868(2003). RN [2] {ECO:0007744|PDB:6YWS, ECO:0007744|PDB:6YWV} RP STRUCTURE BY ELECTRON MICROSCOPY (2.74 ANGSTROMS). RX PubMed=33056988; DOI=10.1038/s41467-020-18830-w; RA Itoh Y., Naschberger A., Mortezaei N., Herrmann J.M., Amunts A.; RT "Analysis of translating mitoribosome reveals functional characteristics of RT translation in mitochondria of fungi."; RL Nat. Commun. 11:5187-5187(2020). CC -!- FUNCTION: Component of the mitochondrial ribosome (mitoribosome), a CC dedicated translation machinery responsible for the synthesis of CC mitochondrial genome-encoded proteins, including at least some of the CC essential transmembrane subunits of the mitochondrial respiratory CC chain. The mitoribosomes are attached to the mitochondrial inner CC membrane and translation products are cotranslationally integrated into CC the membrane. {ECO:0000305|PubMed:33056988}. CC -!- SUBUNIT: Component of the mitochondrial large ribosomal subunit (mt- CC LSU). Mature N.crassa 74S mitochondrial ribosomes consist of a small CC (37S) and a large (54S) subunit. The 37S small subunit contains a 16S CC ribosomal RNA (16S mt-rRNA) and 32 different proteins. The 54S large CC subunit contains a 23S rRNA (23S mt-rRNA) and 42 different proteins. CC {ECO:0000269|PubMed:33056988}. CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:33056988}. CC -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein CC mL41 family. {ECO:0000305}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CM002241; EAA30910.1; -; Genomic_DNA. DR RefSeq; XP_960146.1; XM_955053.2. DR PDB; 6YWS; EM; 2.74 A; 3=1-103. DR PDB; 6YWV; EM; 3.03 A; 3=1-103. DR PDB; 6YWX; EM; 3.10 A; 3=1-103. DR PDBsum; 6YWS; -. DR PDBsum; 6YWV; -. DR PDBsum; 6YWX; -. DR AlphaFoldDB; Q7S5W0; -. DR SMR; Q7S5W0; -. DR STRING; 5141.EFNCRP00000006955; -. DR EnsemblFungi; EAA30910; EAA30910; NCU07057. DR GeneID; 3876293; -. DR KEGG; ncr:NCU07057; -. DR VEuPathDB; FungiDB:NCU07057; -. DR HOGENOM; CLU_131055_3_0_1; -. DR InParanoid; Q7S5W0; -. DR OMA; TTKQGPH; -. DR OrthoDB; 275237at2759; -. DR Proteomes; UP000001805; Chromosome 5, Linkage Group VI. DR GO; GO:0005762; C:mitochondrial large ribosomal subunit; IBA:GO_Central. DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central. DR GO; GO:0006412; P:translation; IBA:GO_Central. DR InterPro; IPR019189; Ribosomal_L27/L41_mit. DR PANTHER; PTHR21338:SF0; 39S RIBOSOMAL PROTEIN L41, MITOCHONDRIAL; 1. DR PANTHER; PTHR21338; MITOCHONDRIAL RIBOSOMAL PROTEIN L41; 1. DR Pfam; PF09809; MRP-L27; 1. PE 1: Evidence at protein level; KW 3D-structure; Mitochondrion; Reference proteome; Ribonucleoprotein; KW Ribosomal protein; Transit peptide. FT CHAIN 1..103 FT /note="Large ribosomal subunit protein mL41" FT /id="PRO_0000458588" SQ SEQUENCE 103 AA; 11776 MW; D59C7695C4760FB1 CRC64; MQPTRILQGL KYRKLRLTTK DVNKGFYKGN RTGSMGTHTS YGTYKIDYTK VRTYVCPDLT GFKLTPFVSK TIRPVHDQFP GDKLGPKNPA TYLARWKSEN GLD //