ID Q7RTW4_HUMAN PRELIMINARY; PRT; 645 AA. AC Q7RTW4; DT 01-MAR-2004 (TrEMBLrel. 26, Created) DT 01-MAR-2004 (TrEMBLrel. 26, Last sequence update) DT 01-MAR-2004 (TrEMBLrel. 26, Last annotation update) DE Neuregulin 1 isoform HRG-beta1. GN Name=NRG1; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=12145742; RA Stefansson H., Sigurdsson E., Steinthorsdottir V., Bjornsdottir S., RA Sigmundsson T., Ghosh S., Brynjolfsson J., Gunnarsdottir S., RA Ivarsson O., Chou T.T., Hjaltason O., Birgisdottir B., Jonsson H., RA Gudnadottir V.G., Gudmundsdottir E., Bjornsson A., Ingvarsson B., RA Ingason A., Sigfusson S., Hardardottir H., Harvey R.P., Brunner D., RA Mutel V., Gonzalo A., Lemke G., Sainz J., Johannesson G., RA Andresson T., Gudbjartsson D., Manolescu A., Frigge M.L., Gurney M.E., RA Kong A., Gulcher J.R., Petursson H., Stefansson K.; RT "Neuregulin 1 and Susceptibility to Schizophrenia."; RL Am. J. Hum. Genet. 71:0-0(2002). CC -!- MISCELLANEOUS: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ third party annotation (TPA) entry. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; BK000383; DAA00041.1; -; Genomic_DNA. DR HSSP; Q12780; 1HRE. DR SMR; Q7RTW4; 175-241. DR GO; GO:0005102; F:receptor binding; IEA. DR GO; GO:0009790; P:embryonic development; IEA. DR InterPro; IPR000742; EGF_2. DR InterPro; IPR006209; EGF_like. DR InterPro; IPR007110; Ig-like. DR InterPro; IPR002154; Neuregulin_1. DR Pfam; PF00008; EGF; 1. DR Pfam; PF00047; ig; 1. DR Pfam; PF02158; Neuregulin; 1. DR PRINTS; PR01089; NEUREGULIN. DR PROSITE; PS00022; EGF_1; UNKNOWN_1. DR PROSITE; PS50026; EGF_3; 1. DR PROSITE; PS50835; IG_LIKE; 1. SQ SEQUENCE 645 AA; 71126 MW; 04B7AFF528CDD628 CRC64; MSERKEGRGK GKGKKKERGS GKKPESAAGS QSPALPPRLK EMKSQESAAG SKLVLRCETS SEYSSLRFKW FKNGNELNRK NKPQNIKIQK KPGKSELRIN KASLADSGEY MCKVISKLGN DSASANITIV ESNEIITGMP ASTEGAYVSS ESPIRISVST EGANTSSSTS TSTTGTSHLV KCAEKEKTFC VNGGECFMVK DLSNPSRYLC KCPNEFTGDR CQNYVMASFY KHLGIEFMEA EELYQKRVLT ITGICIALLV VGIMCVVAYC KTKKQRKKLH DRLRQSLRSE RNNTMNIANG PHHPNPPPEN VQLVNQYVSK NVISSEHIVE REAETSFSTS HYTSTAHHST TVTQTPSHSW SNGHTESILS ESHSVIVMSS VENSRHSSPT GGPRGRLNGT GGPRECNSFL RHARETPDSY RDSPHSERYV SAMTTPARMS PVDFHTPSSP KSPPSEMSPP VSSMTVSMPS MAVSPFMEEE RPLLLVTPPR LREKKFDHHP QQFSSFHHNP AHDSNSLPAS PLRIVEDEEY ETTQEYEPAQ EPVKKLANSR RAKRTKPNGH IANRLEVDSN TSSQSSNSES ETEDERVGED TPFLGIQNPL AASLEATPAF RLADSRTNPA GRFSTQEEIQ ARLSSVIANQ DPIAV //