ID SGF11_ANOGA Reviewed; 182 AA. AC Q7PXG4; DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot. DT 24-MAR-2009, sequence version 5. DT 24-MAR-2009, entry version 28. DE RecName: Full=SAGA-associated factor 11 homolog; GN Name=Sgf11; ORFNames=AGAP001393; OS Anopheles gambiae (African malaria mosquito). OC Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae; OC Anophelinae; Anopheles. OX NCBI_TaxID=7165; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=PEST; RX MEDLINE=22251359; PubMed=12364791; DOI=10.1126/science.1076181; RA Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., RA Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R., RA Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., RA Lai Z., Kraft C.L., Abril J.F., Anthouard V., Arensburger P., RA Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V., RA Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S., RA Center A., Chaturverdi K., Christophides G.K., Chrystal M.A.M., RA Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I., RA Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z., RA Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R., RA Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C.D., Kokoza E., RA Koutsos A., Letunic I., Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., RA Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J.R., RA Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C., RA Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V., RA Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D., RA Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B., Wang A.H., RA Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., RA Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., RA Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., RA Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S., RA Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C., RA Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L.; RT "The genome sequence of the malaria mosquito Anopheles gambiae."; RL Science 298:129-149(2002). CC -!- FUNCTION: Component of the transcription regulatory histone CC acetylation (HAT) complex SAGA, a multiprotein complex that CC activates transcription by remodeling chromatin and mediating CC histone acetylation and deubiquitination. Within the SAGA complex, CC participates to a subcomplex that specifically deubiquitinates CC histone H2B. The SAGA complex is recruited to specific gene CC promoters by activators, where it is required for transcription CC (By similarity). CC -!- SUBUNIT: Component of some SAGA transcription coactivator-HAT CC complexes (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the SGF11 family. CC -!- SIMILARITY: Contains 1 SGF11-type zinc finger. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AAAB01008987; EAA01107.4; ALT_INIT; Genomic_DNA. DR RefSeq; XP_321744.4; -. DR GeneID; 1281785; -. DR KEGG; aga:AgaP_AGAP001393; -. DR VectorBase; AGAP001393; Anopheles gambiae. DR InterPro; IPR013246; Sgf11. DR Pfam; PF08209; Sgf11; 1. PE 3: Inferred from homology; KW Activator; Chromatin regulator; Complete proteome; Metal-binding; KW Nucleus; Transcription; Transcription regulation; Zinc; Zinc-finger. FT CHAIN 1 182 SAGA-associated factor 11 homolog. FT /FTId=PRO_0000367519. FT ZN_FING 98 119 SGF11-type. SQ SEQUENCE 182 AA; 20312 MW; 7E1EC8EBCDB2316D CRC64; MSENDGIHIE YVDEQELKRE FRRFMSDPET REKAANYLYE SLVDETILGI AYEVHHANKT GSGAAVEGEP EDSKPYTIVD QPDTDVFGSS NTKKAIDCHC PNCNRIVAAS RFAPHLEKCM GMGRNSSRIA SRRIANTRDV GTGNYFGGDE DDEDDADWSG EKRKKKISQV RTNGSKKNGK TS //