ID Q7KYS4 PRELIMINARY; PRT; 606 AA. AC Q7KYS4; DT 05-JUL-2004 (TrEMBLrel. 27, Created) DT 05-JUL-2004 (TrEMBLrel. 27, Last sequence update) DT 05-JUL-2004 (TrEMBLrel. 27, Last annotation update) DE Phosphodiesterase 4C. OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Glioblastoma; RX MEDLINE=98091596; PubMed=9429761; DOI=10.1016/S0898-6568(97)00072-7; RA Owens R.J., Lumb S., Rees-Milton K., Russell A., Baldock D., Lang V., RA Crabbe T., Ballesteros M., Perry M.J.; RT "Molecular cloning and expression of a human phosphodiesterase 4C."; RL Cell. Signal. 9:575-585(1997). CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; U88712; AAC51915.1; -. DR GO; GO:0004114; F:3',5'-cyclic-nucleotide phosphodiesterase a...; IEA. DR GO; GO:0003824; F:catalytic activity; IEA. DR GO; GO:0008883; F:glutamyl-tRNA reductase activity; IEA. DR GO; GO:0006779; P:porphyrin biosynthesis; IEA. DR GO; GO:0007165; P:signal transduction; IEA. DR InterPro; IPR003607; Met_phos_hydro. DR InterPro; IPR002073; PDEase. DR Pfam; PF00233; PDEase_I; 1. DR PRINTS; PR00387; PDIESTERASE1. DR SMART; SM00471; HDc; 1. DR PROSITE; PS00126; PDEASE_I; 1. KW Hydrolase; cAMP. SQ SEQUENCE 606 AA; 67718 MW; AC14D9401F5CCDCE CRC64; MQAPVPHSQR RESFLYRSDS DYELSPKAMS RNSSVASDLH GEDMIVTPFA QVLASLRTVR SNVAALARQQ CLGAAKQGPV GNPSSSNQLP PAEDTGQKLA LETLDELDWC LDQLETLQTR HSVGEMASNK FKRILNRELT HLSETSRSGN QVSEYISRTF LDQQTEVELP KVTAEEAPQP MSRISGLHGL CHSASLSSAT VPRFGVQTDQ EEQLAKELED TNKWGLDVFK VAELSGNQPL TAIIFSIFQE RDLLKTFQIP ADTLATYLLM LEGHYHANVA YHNSLHAADV AQSTHVLLAT PALEAVFTDL EILAALFASA IHDVDHPGVS NQFLINTNSE LALMYNDASV LENHHLAVGF KLLQAENCDI FQNLSAKQRL SLRRMVIDMV LATDMSKHMN LLADLKTMVE TKKVTSLGVL LLDNYSDRIQ VLQNLVHCAD LSNPTKPLPL YRQWTDRIMA EFFQQGDRER ESGLDISPMC DKHTASVEKS QVGFIDYIAH PLWETWADLV HPDAQDLLDT LEDNREWYQS KIPRSPSDLT NPERDGPDRF QFELTLEEAE EEDEEEEEEG EETALAKEAL ELPDTELLSP EAGPAPGDLP LDNQRT //