ID Q7KVT3_DROME Unreviewed; 1367 AA. AC Q7KVT3; DT 05-JUL-2004, integrated into UniProtKB/TrEMBL. DT 05-JUL-2004, sequence version 1. DT 06-FEB-2007, entry version 28. DE CG32717-PE, isoform E. GN Name=sdt; ORFNames=Dmel_CG32717; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=20196006; PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., RA Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., RA Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., RA Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [2] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=22426065; PubMed=12537568; RA Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., RA Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., RA George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., RA Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J., RA Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., RA Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.; RT "Finishing a whole-genome shotgun: release 3 of the Drosophila RT melanogaster euchromatic genome sequence."; RL Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002). RN [3] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=22426070; PubMed=12537573; RA Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J.W., Svirskas R., RA Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., RA Ashburner M., Celniker S.E.; RT "The transposable elements of the Drosophila melanogaster euchromatin: RT a genomics perspective."; RL Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002). RN [4] RP NUCLEOTIDE SEQUENCE. RX MEDLINE=22426069; PubMed=12537572; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). RN [5] RP NUCLEOTIDE SEQUENCE. RX PubMed=16110336; DOI=10.1371/journal.pcbi.0010022; RA Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., RA Ashburner M., Anxolabehere D.; RT "Combined evidence annotation of transposable elements in genome RT sequences."; RL PLoS Comput. Biol. 1:166-175(2005). RN [6] RP NUCLEOTIDE SEQUENCE. RG Berkeley Drosophila Genome Project; RA Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R., RA Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E., RA Yu C., Rubin G.; RT "Drosophila melanogaster release 4 sequence."; RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. RN [7] RP NUCLEOTIDE SEQUENCE. RG Drosophila Heterochromatin Genome Project; RA Smith C.D., Shu S., Yandell M.D., Karpen G.H.; RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. RN [8] RP NUCLEOTIDE SEQUENCE. RA Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S., RA Svirskas R., Rubin G.; RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. RN [9] RP NUCLEOTIDE SEQUENCE. RA Celniker S., Carlson J., Kennedy C., Wan K., Frise E., Hoskins R., RA Park S., Svirskas R., Karpen G.; RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. RN [10] RP NUCLEOTIDE SEQUENCE. RG FlyBase; RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Contains 1 PDZ (DHR) domain. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE014298; AAS65284.1; -; Genomic_DNA. DR UniGene; Dm.17605; -. DR HSSP; P31016; 1JXM. DR KEGG; dme:CG32717-PE; -. DR FlyBase; FBgn0003349; sdt. DR GO; GO:0045179; C:apical cortex; IDA:FlyBase. DR GO; GO:0016324; C:apical plasma membrane; TAS:FlyBase. DR GO; GO:0016324; C:apical plasma membrane; IDA:FlyBase. DR GO; GO:0016324; C:apical plasma membrane; NAS:FlyBase. DR GO; GO:0005918; C:septate junction; TAS:FlyBase. DR GO; GO:0035003; C:subapical complex; TAS:FlyBase. DR GO; GO:0004385; F:guanylate kinase activity; TAS:FlyBase. DR GO; GO:0005515; F:protein binding; TAS:FlyBase. DR GO; GO:0045197; P:establishment and/or maintenance of epithel...; TAS:FlyBase. DR GO; GO:0045197; P:establishment and/or maintenance of epithel...; IEP:FlyBase. DR GO; GO:0016332; P:establishment and/or maintenance of polarit...; IMP:FlyBase. DR GO; GO:0001738; P:morphogenesis of a polarized epithelium; TAS:FlyBase. DR GO; GO:0045186; P:zonula adherens assembly; TAS:FlyBase. DR GO; GO:0045186; P:zonula adherens assembly; IMP:FlyBase. DR InterPro; IPR008144; Guanylate_kin. DR InterPro; IPR008145; Guanylt/Ca. DR InterPro; IPR004172; L27. DR InterPro; IPR001478; PDZ. DR InterPro; IPR001452; SH3. DR InterPro; IPR011511; SH3_2. DR Pfam; PF00625; Guanylate_kin; 1. DR Pfam; PF02828; L27; 1. DR Pfam; PF00595; PDZ; 1. DR Pfam; PF07653; SH3_2; 1. DR PRINTS; PR00452; SH3DOMAIN. DR ProDom; PD000066; SH3; 1. DR SMART; SM00072; GuKc; 1. DR SMART; SM00228; PDZ; 1. DR SMART; SM00326; SH3; 1. DR PROSITE; PS00856; GUANYLATE_KINASE_1; 1. DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1. DR PROSITE; PS51022; L27; 1. DR PROSITE; PS50106; PDZ; 1. DR PROSITE; PS50002; SH3; 1. KW Complete proteome; Repeat; SH3 domain. SQ SEQUENCE 1367 AA; 148311 MW; 1D7E0610B05DF6EE CRC64; MRILKQWNRR RSGSSIVVLD GDDLKPCLPD DYISGQHHLN HQQQLQLQQQ LQQQHPLQQQ HYRTHSGDIR EIDQEMLTML SVNQDNGPHR EMAVDCPDTF IARNKTPPRY PPPRPPQKHK KSTNTTTTTT ITALTNNDHA NKMLIVAYHS SHQHEQLQQQ HPSKTSTTTT TIALDVATQN LYNQKQQNKL EQIENYENCL QSERNEQHEQ QFEQQKQHQA TTAMAATQVA QQQTPSHKLQ ATLSSDPNGN SNSNNNSHIV GISSSSSSNN SSITDDFLCV VDGLYQGRKD TASPSSSAFD EVMSKHTLDS FGSIAYRHLH QQHQATSNGN SSSNTSNTNS NTNSNTNSNS NTNGNTSNNT AVSTKTATVT KTGVSSSNSN SNSLNSSNSS MHTSSSSSGH SSNIASATSS SSATSSSTVP DDLSLAPPGY EVSQQQQQQH LVATPVTMLL PPMAKHRELP VDVPDSFIEM VKTTPRYPPP AHLSSRGSLL SNGSASTAHT TLSSMGVAPS PVTATAAAAA SASAACATTA VAAAAVSGVA DGDARRVADE LNGNAKPVPP PRDHLRVEKD GRLVNCSPAP QLPDRRAPGN ASSGSSGATT HPLQHQQIAQ IVEPTLEQLD SIKKYQEQLR RRREEEERIA QQNEFLRNSL RGSRKLKALQ DTATPGKAVA QQQQQATLAT QVVGVENEAY LPDEDQPQAE QIDGYGELIA ALTRLQNQLS KSGLSTLAGR VSAAHSVLAS ASVAHVLAAR TAVLQRRRSR VSGPLHHSSL GLQKDIVELL TQSNTAAAIE LGNLLTSHEM EGLLLAHDRI ANHTDGTPSP TPTPTPAIGA ATGSTLSSPV AGPKRNLGMV VPPPVVPPPL AQRGAMPLPR GESPPPVPMP PLATMPMSMP VNLPMSACFG TLNDQNDNIR IIQIEKSTEP LGATVRNEGE AVVIGRIVRG GAAEKSGLLH EGDEILEVNG QELRGKTVNE VCALLGAMQG TLTFLIVPAG SPPSVGVMGG TTGSQLAGLG GAHRDTAVLH VRAHFDYDPE DDLYIPCREL GISFQKGDVL HVISREDPNW WQAYREGEED QTLAGLIPSQ SFQHQRETMK LAIAEEAGLA RSRGKDGSGS KGATLLCARK GRKKKKKASS EAGYPLYATT APDETDPEEI LTYEEVALYY PRATHKRPIV LIGPPNIGRH ELRQRLMADS ERFSAAVPHT SRARREGEVP GVDYHFITRQ AFEADILARR FVEHGEYEKA YYGTSLEAIR TVVASGKICV LNLHPQSLKL LRASDLKPYV VLVAPPSLDK LRQKKLRNGE PFKEEELKDI IATARDMEAR WGHLFDMIII NNDTERAYHQ LLAEINSLER EPQWVPAQWV HNNRDES //