ID Q7KVG9_DROME Unreviewed; 596 AA. AC Q7KVG9; DT 05-JUL-2004, integrated into UniProtKB/TrEMBL. DT 05-JUL-2004, sequence version 1. DT 25-OCT-2017, entry version 124. DE SubName: Full=Chip, isoform B {ECO:0000313|EMBL:AAM68293.2}; DE SubName: Full=RE67266p {ECO:0000313|EMBL:ADI46811.1}; GN Name=Chi {ECO:0000313|EMBL:AAM68293.2, GN ECO:0000313|FlyBase:FBgn0013764}; GN Synonyms=CG3924 {ECO:0000313|FlyBase:FBgn0013764}, Chi-RB GN {ECO:0000313|EMBL:ADI46811.1}; GN ORFNames=Dmel_CG3924 {ECO:0000313|EMBL:AAM68293.2}; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227 {ECO:0000313|EMBL:AAM68293.2, ECO:0000313|Proteomes:UP000000803}; RN [1] {ECO:0000313|EMBL:AAM68293.2, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., RA Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., RA Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., RA Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [2] {ECO:0000313|EMBL:AAM68293.2, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537568; RA Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., RA Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., RA George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., RA Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J., RA Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., RA Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.; RT "Finishing a whole-genome shotgun: release 3 of the Drosophila RT melanogaster euchromatic genome sequence."; RL Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002). RN [3] {ECO:0000313|EMBL:AAM68293.2, ECO:0000313|Proteomes:UP000000803} RP GENOME REANNOTATION. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfied E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). RN [4] {ECO:0000313|EMBL:AAM68293.2, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537573; RA Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., RA Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., RA Ashburner M., Celniker S.E.; RT "The transposable elements of the Drosophila melanogaster euchromatin: RT a genomics perspective."; RL Genome Biol. 3:RESEARCH0084.1-RESEARCH0084.20(2002). RN [5] {ECO:0000313|EMBL:AAM68293.2, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=12537574; RA Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., RA Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., RA Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., RA Karpen G.H.; RT "Heterochromatic sequences in a Drosophila whole-genome shotgun RT assembly."; RL Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002). RN [6] {ECO:0000313|EMBL:AAM68293.2, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=16110336; DOI=10.1371/journal.pcbi.0010022; RA Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., RA Ashburner M., Anxolabehere D.; RT "Combined evidence annotation of transposable elements in genome RT sequences."; RL PLoS Comput. Biol. 1:166-175(2005). RN [7] {ECO:0000313|EMBL:AAM68293.2} RP NUCLEOTIDE SEQUENCE. RA Celniker S., Carlson J., Wan K., Frise E., Hoskins R., Park S., RA Svirskas R., Rubin G.; RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases. RN [8] {ECO:0000313|EMBL:AAM68293.2} RP NUCLEOTIDE SEQUENCE. RG Berkeley Drosophila Genome Project; RA Celniker S., Carlson J., Wan K., Pfeiffer B., Frise E., George R., RA Hoskins R., Stapleton M., Pacleb J., Park S., Svirskas R., Smith E., RA Yu C., Rubin G.; RT "Drosophila melanogaster release 4 sequence."; RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases. RN [9] {ECO:0000313|EMBL:AAM68293.2, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569856; DOI=10.1126/science.1139815; RA Smith C.D., Shu S., Mungall C.J., Karpen G.H.; RT "The Release 5.1 annotation of Drosophila melanogaster RT heterochromatin."; RL Science 316:1586-1591(2007). RN [10] {ECO:0000313|EMBL:AAM68293.2, ECO:0000313|Proteomes:UP000000803} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley {ECO:0000313|Proteomes:UP000000803}; RX PubMed=17569867; DOI=10.1126/science.1139816; RA Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M., RA Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A., RA Dimitri P., Karpen G.H., Celniker S.E.; RT "Sequence finishing and mapping of Drosophila melanogaster RT heterochromatin."; RL Science 316:1625-1628(2007). RN [11] {ECO:0000313|EMBL:ADI46811.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=Berkeley {ECO:0000313|EMBL:ADI46811.1}; RA Carlson J., Booth B., Frise E., Park S., Wan K., Yu C., Celniker S.; RL Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases. RN [12] {ECO:0000313|EMBL:AAM68293.2} RP NUCLEOTIDE SEQUENCE. RG FlyBase; RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE013599; AAM68293.2; -; Genomic_DNA. DR EMBL; BT125015; ADI46811.1; -; mRNA. DR RefSeq; NP_726403.2; NM_166650.2. DR UniGene; Dm.6987; -. DR SMR; Q7KVG9; -. DR STRING; 7227.FBpp0072101; -. DR EnsemblMetazoa; FBtr0072192; FBpp0072101; FBgn0013764. DR GeneID; 37837; -. DR UCSC; CG3924-RB; d. melanogaster. DR CTD; 37837; -. DR FlyBase; FBgn0013764; Chi. DR eggNOG; KOG2181; Eukaryota. DR eggNOG; ENOG410YZVH; LUCA. DR GeneTree; ENSGT00390000005639; -. DR OMA; RRGLNTG; -. DR OrthoDB; EOG091G0A0P; -. DR Reactome; R-DME-8939236; RUNX1 regulates transcription of genes involved in differentiation of HSCs. DR GenomeRNAi; 37837; -. DR Proteomes; UP000000803; Chromosome 2R. DR Bgee; FBgn0013764; -. DR ExpressionAtlas; Q7KVG9; differential. DR GO; GO:0005634; C:nucleus; IDA:FlyBase. DR GO; GO:0001085; F:RNA polymerase II transcription factor binding; IPI:FlyBase. DR GO; GO:0008134; F:transcription factor binding; IPI:FlyBase. DR GO; GO:0007411; P:axon guidance; IMP:FlyBase. DR GO; GO:0007350; P:blastoderm segmentation; TAS:FlyBase. DR GO; GO:0022416; P:chaeta development; IMP:FlyBase. DR GO; GO:0008407; P:chaeta morphogenesis; IMP:FlyBase. DR GO; GO:0048749; P:compound eye development; IMP:FlyBase. DR GO; GO:0070983; P:dendrite guidance; IMP:FlyBase. DR GO; GO:0035050; P:embryonic heart tube development; IMP:FlyBase. DR GO; GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase. DR GO; GO:0007399; P:nervous system development; IMP:FlyBase. DR GO; GO:0006909; P:phagocytosis; IMP:FlyBase. DR GO; GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:FlyBase. DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:FlyBase. DR GO; GO:0007563; P:regulation of eclosion; IMP:FlyBase. DR GO; GO:0010468; P:regulation of gene expression; IMP:FlyBase. DR GO; GO:0008593; P:regulation of Notch signaling pathway; IMP:FlyBase. DR InterPro; IPR029005; LIM-bd/SEUSS. DR PANTHER; PTHR10378; PTHR10378; 1. DR Pfam; PF01803; LIM_bind; 2. PE 2: Evidence at transcript level; KW Complete proteome {ECO:0000313|Proteomes:UP000000803}; KW Reference proteome {ECO:0000313|Proteomes:UP000000803}. SQ SEQUENCE 596 AA; 64779 MW; B7BB0687580A46D5 CRC64; MQCDIQTSRR ECPIEPTTGM NRRGLNAGNT MTSQANIDDG SWKAVSEGGS MLPASNSAVL NPDGSNQSGF AQGGLPYNSA GNPYPPAGQS SPAGNQSIVF QNSNQPGSNT PQYTSSPAPS GSSTPGPVGA QNIPGNYPQS ATAGNFNGPV GGPFGSPSSG LGQFSRPASS GTPFNSGQAG HFSSPTVFSV GGQFNPMPPA SPFGHGGNHP MMGGPQQMER IDQGFRRHNS YFSHTEHRVF ELNKRLQQRN EESDNCWWDS FTTEFFEDDA RLTILFCLED GPKRYTIGRT LIPRFFRSIY EGGVSDLYFQ LKHAKESFHN TSITLDCDQC TVITQHGKPF FTKVCADARL ILEFMYDDYM RIKSWHMTIK GHRELIPRSV IGTSLPPDPM LLDQITKNIT RAGITNSTLN YLRLCVILEP MQELMSRHKA YALSPRDCLK TTLFQKWQRM VAPPGKKDPQ RPPNKRRKRK GSNSGGGNNS NTPPVTNQKR SPSGPSFSLS SQDVMVVGEP TLMGGEFGEE DERLITRLEN TQYDGTNAVE HDNHTGFGHA DSPISGSNPW SIDRAGAIPA SPGNGAAPQN NANISDIDKK SPIVSQ //