ID   Q76HH2_THUAA            Unreviewed;       348 AA.
AC   Q76HH2;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   11-JUN-2014, entry version 50.
DE   RecName: Full=NADH-ubiquinone oxidoreductase chain 2;
DE            EC=1.6.5.3;
GN   Name=ND2;
OS   Thunnus alalunga (Albacore) (Scomber alalunga).
OG   Mitochondrion.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Pelagimorpharia; Scombriformes; Scombridae; Thunnus.
OX   NCBI_TaxID=8235;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RA   Manchado M., Catanese G., Infante C.;
RT   "Complete mitochondrial DNA sequence of albacore (Thunnus alalunga).";
RL   Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RA   Martinez Ibarra C., Ishizaki S., Nagashima Y.;
RT   "Development of a PCR-based method for differentiation of tuna and
RT   related species in canned products.";
RL   Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE.
RA   Martinez Ibarra C., Ishizaki S., Nagashima Y.;
RT   "Development of a PCR-based method for differentiation of tuna and
RT   related species in canned products.";
RL   Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Core subunit of the mitochondrial membrane respiratory
CC       chain NADH dehydrogenase (Complex I) that is believed to belong to
CC       the minimal assembly required for catalysis. Complex I functions
CC       in the transfer of electrons from NADH to the respiratory chain.
CC       The immediate electron acceptor for the enzyme is believed to be
CC       ubiquinone (By similarity).
CC   -!- CATALYTIC ACTIVITY: NADH + ubiquinone + 5 H(+)(In) = NAD(+) +
CC       ubiquinol + 4 H(+)(Out).
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass
CC       membrane protein (By similarity).
CC   -!- SIMILARITY: Belongs to the complex I subunit 2 family.
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DR   EMBL; GU256526; ADA69862.1; -; Genomic_DNA.
DR   EMBL; JN086151; AEI53252.1; -; Genomic_DNA.
DR   EMBL; AB101291; BAD06493.1; -; Genomic_DNA.
DR   RefSeq; NP_955706.1; NC_005317.1.
DR   GeneID; 2702240; -.
DR   CTD; 4536; -.
DR   HOVERGEN; HBG016692; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0070469; C:respiratory chain; IEA:UniProtKB-KW.
DR   GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006120; P:mitochondrial electron transport, NADH to ubiquinone; IEA:InterPro.
DR   InterPro; IPR010933; NADH_DH_su2_C.
DR   InterPro; IPR001750; NADH_UbQ/plastoQ_OxRdtase.
DR   InterPro; IPR003917; NADH_UbQ_OxRdtase_chain2.
DR   Pfam; PF06444; NADH_dehy_S2_C; 1.
DR   Pfam; PF00361; Oxidored_q1; 1.
DR   PRINTS; PR01436; NADHDHGNASE2.
PE   3: Inferred from homology;
KW   Electron transport; Membrane; Mitochondrion;
KW   Mitochondrion inner membrane; NAD; Oxidoreductase; Respiratory chain;
KW   Transmembrane; Transmembrane helix; Transport; Ubiquinone.
SQ   SEQUENCE   348 AA;  37632 MW;  F0C05ECF3CECBA9F CRC64;
     MNPYILATLL FGLGLGTTIT FASSHWLLAW MGLEMNTLAI IPLMAQNHHP RAVEATTKYF
     LTQATAAAML LFASTTNAWL TGQWNIEQMT HPIPTTMIML ALALKIGLAP VHAWLPEVLQ
     GLDLTTGLIL STWQKLAPFA LILQIHPTNP ALLIVLGVAS TLVGGWGGLN QTQLRKILAY
     SSIAHLGWMI LILQFSPSLT LLTLLTYFIM TFSAFLVFKL NKATNINTLA TSWAKAPALT
     SLTPLVLLSL GGLPPLTGFM PKWLILQELS KQDLAPVATL AALSALLSLY FYLRLSYAMT
     LTMSPNNLSG TASWRLPSLQ PTLPVATSLV ATLALLPLTP AITAILTL
//