ID SYG_MYCPA STANDARD; PRT; 463 AA. AC Q73Y21; DT 15-FEB-2005, integrated into UniProtKB/Swiss-Prot. DT 05-JUL-2004, sequence version 1. DT 04-APR-2006, entry version 20. DE Glycyl-tRNA synthetase (EC 6.1.1.14) (Glycine--tRNA ligase) (GlyRS). GN Name=glyQS; Synonyms=glyS; OrderedLocusNames=MAP_2137c; OS Mycobacterium paratuberculosis. OC Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales; OC Corynebacterineae; Mycobacteriaceae; Mycobacterium; OC Mycobacterium avium complex (MAC). OX NCBI_TaxID=1770; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=k10; RA Li L., Bannantine J., Zhang Q., Amonsin A., Alt D., Kapur V.; RL Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases. CC -!- CATALYTIC ACTIVITY: ATP + glycine + tRNA(Gly) = AMP + diphosphate CC + glycyl-tRNA(Gly). CC -!- SUBUNIT: Homodimer (By similarity). CC -!- SUBCELLULAR LOCATION: Cytoplasm. CC -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase CC family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AE016958; AAS04454.1; -; Genomic_DNA. DR HSSP; P56206; 1ATI. DR HAMAP; MF_00253; -; 1. DR InterPro; IPR004154; Anticodon_bd. DR InterPro; IPR002314; tRNA-synt_2b. DR InterPro; IPR002315; tRNA-synt_gly. DR InterPro; IPR006195; tRNA_ligase_II. DR PANTHER; PTHR10745; tRNA-synt_gly; 1. DR Pfam; PF03129; HGTP_anticodon; 1. DR Pfam; PF00587; tRNA-synt_2b; 1. DR PRINTS; PR01043; TRNASYNTHGLY. DR TIGRFAMs; TIGR00389; glyS_dimeric; 1. DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1. KW Aminoacyl-tRNA synthetase; ATP-binding; Complete proteome; Ligase; KW Nucleotide-binding; Protein biosynthesis. FT CHAIN 1 463 Glycyl-tRNA synthetase. FT /FTId=PRO_0000072966. SQ SEQUENCE 463 AA; 52971 MW; F602B4C500CFEB2D CRC64; MHRLVASVID TVVNLAKRRG FVYPSGEIYG GTRSAWDYGP LGVEFKENIK RQWWRSVVTG REDVVGLDSS IILPRQVWVA SGHVEVFHDP LVESLITHKR YRADHLIEAY EAKHGHPPPN GLADIRDPDT GEPGRWTEPR EFNMMLKTYL GPIETEEGLH YLRPETAQGI FVNFANVVTT ARKKPPFGIG QIGKSFRNEI TPGNFIFRTR EFEQMEMEFF VEPSTAKEWH QYWIDTRLQW YVELGIDPQN LRLFEHPADK LSHYSDRTVD IEYKFGFAGN PWGELEGVAN RTDFDLSTHS KHSGVDLSFY DQATDSRYIP YVIEPAAGLT RSFMAFLIDA YVEDEAPNAK GKMEKRAVLR LDPRLAPVKA AVLPLSRHAD LSPKARDLAA ELRRFWNIEF DDAGAIGRRY RRQDEIGTPF CVTVDFDSLE DNAVTVRRRD DMSQERIGMD AVADYLSARL KGC //