ID   Q71G59_DANRE            Unreviewed;       475 AA.
AC   Q71G59;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   01-APR-2015, entry version 81.
DE   SubName: Full=Matrix metalloproteinase 13 {ECO:0000313|EMBL:AAQ07962.1};
GN   Name=mmp13a {ECO:0000313|ZFIN:ZDB-GENE-031202-2};
GN   Synonyms=mmp13 {ECO:0000313|ZFIN:ZDB-GENE-031202-2};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|EMBL:AAQ07962.1};
RN   [1] {ECO:0000313|EMBL:AAQ07962.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Bai S., Sarras M.P.Jr.;
RT   "Cloning and Functional Analysis of Zebrafish MMP13.";
RL   Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Contains hemopexin repeats.
CC       {ECO:0000256|SAAS:SAAS00018506}.
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DR   EMBL; AF506756; AAQ07962.1; -; mRNA.
DR   UniGene; Dr.81475; -.
DR   ProteinModelPortal; Q71G59; -.
DR   SMR; Q71G59; 103-268.
DR   STRING; 7955.ENSDARP00000026466; -.
DR   MEROPS; M10.013; -.
DR   ZFIN; ZDB-GENE-031202-2; mmp13a.
DR   HOGENOM; HOG000217927; -.
DR   HOVERGEN; HBG052484; -.
DR   GO; GO:0031012; C:extracellular matrix; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 2.110.10.10; -; 1.
DR   Gene3D; 3.40.390.10; -; 1.
DR   InterPro; IPR000585; Hemopexin-like_dom.
DR   InterPro; IPR018487; Hemopexin-like_repeat.
DR   InterPro; IPR018486; Hemopexin_CS.
DR   InterPro; IPR024079; MetalloPept_cat_dom.
DR   InterPro; IPR001818; Pept_M10_metallopeptidase.
DR   InterPro; IPR021190; Pept_M10A.
DR   InterPro; IPR016293; Pept_M10A_stromelysin-type.
DR   InterPro; IPR021158; Pept_M10A_Zn_BS.
DR   InterPro; IPR006026; Peptidase_Metallo.
DR   InterPro; IPR002477; Peptidoglycan-bd-like.
DR   Pfam; PF00045; Hemopexin; 3.
DR   Pfam; PF00413; Peptidase_M10; 1.
DR   Pfam; PF01471; PG_binding_1; 1.
DR   PIRSF; PIRSF001191; Peptidase_M10A_matrix; 1.
DR   PRINTS; PR00138; MATRIXIN.
DR   SMART; SM00120; HX; 4.
DR   SMART; SM00235; ZnMc; 1.
DR   SUPFAM; SSF47090; SSF47090; 1.
DR   SUPFAM; SSF50923; SSF50923; 1.
DR   PROSITE; PS00546; CYSTEINE_SWITCH; 1.
DR   PROSITE; PS00024; HEMOPEXIN; 1.
DR   PROSITE; PS51642; HEMOPEXIN_2; 4.
PE   2: Evidence at transcript level;
KW   Calcium {ECO:0000256|SAAS:SAAS00018654};
KW   Disulfide bond {ECO:0000256|SAAS:SAAS00018688};
KW   Hydrolase {ECO:0000256|SAAS:SAAS00082158};
KW   Metal-binding {ECO:0000256|SAAS:SAAS00082048};
KW   Metalloprotease {ECO:0000256|SAAS:SAAS00111647};
KW   Protease {ECO:0000256|SAAS:SAAS00082023};
KW   Repeat {ECO:0000256|SAAS:SAAS00018676};
KW   Zinc {ECO:0000256|SAAS:SAAS00082033}.
FT   ACT_SITE    223    223       {ECO:0000256|PIRSR:PIRSR001191-1}.
SQ   SEQUENCE   475 AA;  53792 MW;  90F93E82B37B2CFD CRC64;
     MKTCFRLCVF ITLLFSGHSS PIAPPAGGDQ DTLAENYLTR LYGLPKPAQN PSPSGGEKRS
     SDVSLRLKEM QQFFKLKVSG KLDQETLEVM KKPRCGVPDI KAYSTFAGDY KWKKHQLTYR
     IGNYTPDMSV AEVDDSISKA LKVWADVTPL RFTRIYSGTA DIMISFATGD HRDGYPFDGP
     NGFLAHAFPP FEGIGGDAHF DDDETFSYRS PQYYNLFLVA AHEFGHSLGL EHSQDPGALM
     YPTYVYRDVD RFVLPRDDVN GIQSLYGPNT DVNTDDSKPT PPVTPNTCDP NLVLDAVTML
     RGEIMFFKNS FFWRSYPQSA DVEQQLIKSF WPEAPDNIDA AFESVMQDKV FLIKGEKVWA
     LYGYDMVQGY PKSLSMFRLP KNVRKIDAVL YKEDSNSILF FANNQVYSYN EGIRQMDKGF
     PKPVEEVFPG MTGKVTAAFQ YRGLNYLFSG SKMLEFGSNN RLFRVLNNNY FLPCK
//