ID Q71FH3_FOSFO Unreviewed; 379 AA. AC Q71FH3; DT 05-JUL-2004, integrated into UniProtKB/TrEMBL. DT 05-JUL-2004, sequence version 1. DT 10-MAY-2017, entry version 67. DE RecName: Full=Cytochrome b {ECO:0000256|RuleBase:RU362117}; GN Name=cytb {ECO:0000313|EMBL:AAQ08038.1}; OS Fossa fossana (Malagasy civet) (Viverra fossa). OG Mitochondrion {ECO:0000313|EMBL:AAQ08038.1}. OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Eupleridae; OC Euplerinae; Fossa. OX NCBI_TaxID=143320 {ECO:0000313|EMBL:AAQ08038.1}; RN [1] {ECO:0000313|EMBL:AAQ08038.1} RP NUCLEOTIDE SEQUENCE. RC STRAIN=C-69 {ECO:0000313|EMBL:AAQ08038.1}; RA Gaubert P., Tranier M., Delmas A.-S., Colyn M., Veron G.; RT "First molecular evidence for reassessing phylogenetic affinities RT between genets (Genetta) and the enigmatic genet-like taxa RT Osbornictis, Poiana and Prionodon (Carnivora, Viverridae)."; RL Zool. Scr. 33:117-129(2004). CC -!- FUNCTION: Component of the ubiquinol-cytochrome c reductase CC complex (complex III or cytochrome b-c1 complex) that is part of CC the mitochondrial respiratory chain. The b-c1 complex mediates CC electron transfer from ubiquinol to cytochrome c. Contributes to CC the generation of a proton gradient across the mitochondrial CC membrane that is then used for ATP synthesis. CC {ECO:0000256|RuleBase:RU362117}. CC -!- COFACTOR: CC Name=heme; Xref=ChEBI:CHEBI:30413; CC Evidence={ECO:0000256|RuleBase:RU362117}; CC Note=Binds 2 heme groups non-covalently. CC {ECO:0000256|RuleBase:RU362117}; CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane CC {ECO:0000256|RuleBase:RU362117}. CC -!- SIMILARITY: Belongs to the cytochrome b family. CC {ECO:0000256|RuleBase:RU362117}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AF511062; AAQ08038.1; -; Genomic_DNA. DR ProteinModelPortal; Q71FH3; -. DR HOVERGEN; HBG017694; -. DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. DR GO; GO:0045275; C:respiratory chain complex III; IEA:InterPro. DR GO; GO:0009055; F:electron carrier activity; IEA:InterPro. DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule. DR GO; GO:0008121; F:ubiquinol-cytochrome-c reductase activity; IEA:InterPro. DR GO; GO:0006122; P:mitochondrial electron transport, ubiquinol to cytochrome c; IEA:InterPro. DR CDD; cd00290; cytochrome_b_C; 1. DR CDD; cd00284; Cytochrome_b_N; 1. DR Gene3D; 1.20.810.10; -; 1. DR InterPro; IPR005798; Cyt_b/b6_C. DR InterPro; IPR005797; Cyt_b/b6_N. DR InterPro; IPR027387; Cytb/b6-like. DR InterPro; IPR030689; Cytochrome_b. DR InterPro; IPR016174; Di-haem_cyt_TM. DR Pfam; PF00032; Cytochrom_B_C; 1. DR Pfam; PF00033; Cytochrome_B; 1. DR PIRSF; PIRSF038885; COB; 1. DR SUPFAM; SSF81342; SSF81342; 1. DR SUPFAM; SSF81648; SSF81648; 1. DR PROSITE; PS51003; CYTB_CTER; 1. DR PROSITE; PS51002; CYTB_NTER; 1. PE 3: Inferred from homology; KW Electron transport {ECO:0000256|RuleBase:RU362117}; KW Heme {ECO:0000256|RuleBase:RU362117}; KW Iron {ECO:0000256|RuleBase:RU362117}; KW Membrane {ECO:0000256|RuleBase:RU362117}; KW Metal-binding {ECO:0000256|RuleBase:RU362117}; KW Mitochondrion {ECO:0000256|RuleBase:RU362117, KW ECO:0000313|EMBL:AAQ08038.1}; KW Respiratory chain {ECO:0000256|RuleBase:RU362117}; KW Transmembrane {ECO:0000256|RuleBase:RU362117}; KW Transmembrane helix {ECO:0000256|RuleBase:RU362117}; KW Transport {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 30 56 Helical. {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 77 98 Helical. {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 113 133 Helical. {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 140 158 Helical. {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 178 200 Helical. {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 229 250 Helical. {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 288 307 Helical. {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 319 338 Helical. {ECO:0000256|RuleBase:RU362117}. FT TRANSMEM 344 368 Helical. {ECO:0000256|RuleBase:RU362117}. FT DOMAIN 1 209 CYTB_NTER. {ECO:0000259|PROSITE:PS51002}. FT DOMAIN 210 379 CYTB_CTER. {ECO:0000259|PROSITE:PS51003}. SQ SEQUENCE 379 AA; 42643 MW; 95E9BAF31FCE6288 CRC64; MTNIRKSHPL IKIINESFID LPAPSNISAW WNFGSLLGVC LILQILTGLF LAMHYTSDTA TAFSSVTHIC RDVNYGWIIR YMHANGASMF FICLFMHVGR GMYYGSHTFS ETWNIGILLL FAVMATAFMG YVLPWGQMSF WGATVITNLL SAIPYIGTNL VEWIWGGFSV DKATLTRFFA FHFILPFIIS ALAAVHLLFL HETGSNNPSG MPSDSDKIPF HPYYTFKDIL GVLLLILXLT ILVLFSRTYL GDADDYTPAN PLYTPPHIKP EWYFLFAYAI LRSIPNKLGG VMALVLSILI LAILPLLNTS KQRGMMFRPL SQCLFWLLVA DLLTLTWIGG QPVAYPFITI GQLASILYFL TILILMPISG IIENQLLMW //