ID Q70V12_HUMAN Unreviewed; 107 AA. AC Q70V12; DT 05-JUL-2004, integrated into UniProtKB/TrEMBL. DT 05-JUL-2004, sequence version 1. DT 02-JUN-2021, entry version 51. DE SubName: Full=ABO blood group (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase) {ECO:0000313|EMBL:CCD83328.1}; DE SubName: Full=ABO glycosyltransferase {ECO:0000313|EMBL:CAD60238.1}; DE Flags: Fragment; GN Name=ABO {ECO:0000313|EMBL:CAD60238.1}; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; OC Homo. OX NCBI_TaxID=9606 {ECO:0000313|EMBL:CAD60238.1}; RN [1] {ECO:0000313|EMBL:CAD60238.1} RP NUCLEOTIDE SEQUENCE. RC TISSUE=Peripheral {ECO:0000313|EMBL:CAD60238.1}; RA Seltsam A., Hallensleben M., Kollmann A., Blasczyk R.; RT "Nature of diversity and diversification at the ABO locus."; RL Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases. RN [2] {ECO:0000313|EMBL:CCD83328.1} RP NUCLEOTIDE SEQUENCE. RC TISSUE=Whole blood {ECO:0000313|EMBL:CCD83328.1}; RA Stabentheiner S., Danzer M., Polin H., Gabriel C.; RT "Haplotype specific extraction provides a useful tool for ABO allele RT identification."; RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases. CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single- CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}. CC -!- SIMILARITY: Belongs to the glycosyltransferase 6 family. CC {ECO:0000256|ARBA:ARBA00010413}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AJ536151; CAD60238.1; -; Genomic_DNA. DR EMBL; HE601936; CCD83328.1; -; Genomic_DNA. DR ChiTaRS; ABO; human. DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW. DR GO; GO:0016758; F:transferase activity, transferring hexosyl groups; IEA:InterPro. DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro. DR InterPro; IPR005076; Glyco_trans_6. DR PANTHER; PTHR10462; PTHR10462; 1. DR Pfam; PF03414; Glyco_transf_6; 1. PE 3: Inferred from homology; KW Glycosyltransferase {ECO:0000313|EMBL:CCD83328.1}; KW Membrane {ECO:0000256|SAM:Phobius}; KW Transferase {ECO:0000313|EMBL:CAD60238.1}; KW Transmembrane {ECO:0000256|SAM:Phobius}; KW Transmembrane helix {ECO:0000256|SAM:Phobius}. FT TRANSMEM 6..27 FT /note="Helical" FT /evidence="ECO:0000256|SAM:Phobius" FT REGION 85..107 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT COMPBIAS 86..107 FT /note="Polar residues" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:CAD60238.1" SQ SEQUENCE 107 AA; 11771 MW; B8E42DA9DD764E95 CRC64; KPKCHALRPM ILFLIMLVLV LFGYGFLSPR SLMPGSLERG FCMAVREPDH LQHVSLPRMV YPQPKVLTPC RKDVLVVPLG WLPLSGRARS TSTSSTSSSG SRTPPLG //