ID Q708D1_GLOMR Unreviewed; 95 AA. AC Q708D1; DT 05-JUL-2004, integrated into UniProtKB/TrEMBL. DT 05-JUL-2004, sequence version 1. DT 29-MAY-2024, entry version 84. DE SubName: Full=Engrailed protein {ECO:0000313|EMBL:CAE83645.1}; DE Flags: Fragment; GN Name=en {ECO:0000313|EMBL:CAE83645.1}; OS Glomeris marginata (Pill millipede). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Myriapoda; Diplopoda; OC Pentazonia; Glomerida; Glomeridae; Glomeris. OX NCBI_TaxID=62006 {ECO:0000313|EMBL:CAE83645.1}; RN [1] {ECO:0000313|EMBL:CAE83645.1} RP NUCLEOTIDE SEQUENCE. RX PubMed=15031107; DOI=10.1016/j.ydbio.2003.12.021; RA Janssen R., Prpic N.M., Damen W.G.; RT "Gene expression suggests decoupled dorsal and ventral segmentation in the RT millipede Glomeris marginata (Myriapoda: Diplopoda)."; RL Dev. Biol. 268:89-104(2004). CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123, CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}. CC -!- SIMILARITY: Belongs to the engrailed homeobox family. CC {ECO:0000256|ARBA:ARBA00010896}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AJ616904; CAE83645.1; -; mRNA. DR AlphaFoldDB; Q708D1; -. DR GO; GO:0016586; C:RSC-type complex; IEA:TreeGrafter. DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro. DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:TreeGrafter. DR GO; GO:0030182; P:neuron differentiation; IEA:TreeGrafter. DR CDD; cd00086; homeodomain; 1. DR Gene3D; 1.10.10.60; Homeodomain-like; 1. DR InterPro; IPR009057; Homeobox-like_sf. DR InterPro; IPR017970; Homeobox_CS. DR InterPro; IPR001356; Homeobox_dom. DR InterPro; IPR000747; Homeobox_engrailed. DR InterPro; IPR020479; Homeobox_metazoa. DR PANTHER; PTHR24341; HOMEOBOX PROTEIN ENGRAILED; 1. DR PANTHER; PTHR24341:SF6; HOMEOBOX PROTEIN INVECTED-RELATED; 1. DR Pfam; PF00046; Homeodomain; 1. DR PRINTS; PR00026; ENGRAILED. DR PRINTS; PR00024; HOMEOBOX. DR SMART; SM00389; HOX; 1. DR SUPFAM; SSF46689; Homeodomain-like; 1. DR PROSITE; PS00027; HOMEOBOX_1; 1. DR PROSITE; PS50071; HOMEOBOX_2; 1. PE 2: Evidence at transcript level; KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE- KW ProRule:PRU00108}; KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE- KW ProRule:PRU00108}; KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE- KW ProRule:PRU00108}. FT DOMAIN 24..84 FT /note="Homeobox" FT /evidence="ECO:0000259|PROSITE:PS50071" FT DNA_BIND 26..85 FT /note="Homeobox" FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108" FT REGION 1..34 FT /note="Disordered" FT /evidence="ECO:0000256|SAM:MobiDB-lite" FT NON_TER 1 FT /evidence="ECO:0000313|EMBL:CAE83645.1" FT NON_TER 95 FT /evidence="ECO:0000313|EMBL:CAE83645.1" SQ SEQUENCE 95 AA; 11420 MW; AC6C59A3ABD2CC11 CRC64; RYSDRPSSGR SPRSRRAKKK DKKPEEKRPR TAFTNEQLAR LKKEFQENRY LTEKRRQDLA RELKLNESQI KIWFQNKRAK IKKASGQRNG LALHL //