ID Q701L7_HUMAN PRELIMINARY; PRT; 513 AA. AC Q701L7; DT 05-JUL-2004 (TrEMBLrel. 27, Created) DT 05-JUL-2004 (TrEMBLrel. 27, Last sequence update) DT 05-JUL-2004 (TrEMBLrel. 27, Last annotation update) DE Type II hair keratin 2. GN Name=KRTHB2; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Primates; Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Human scalp; RX PubMed=10692104; DOI=10.1046/j.1523-1747.2000.00910.x; RA Rogers M.A., Winter H., Langbein L., Wolf C., Schweizer J.; RT "Characterization of a 300 kbp region of human DNA containing the type RT II hair keratin gene domain."; RL J. Invest. Dermatol. 114:464-472(2000). RN [2] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Human scalp; RA Rogers M.A., Langbein L., Smith F.J.D., Mclean W.H.I., Winter H., RA Beckmann I., Praetzel S., Schweizer J.; RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases. CC -!- SIMILARITY: Belongs to the intermediate filament family. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; AJ628419; CAF31523.1; -. DR GO; GO:0005882; C:intermediate filament; IEA. DR GO; GO:0005198; F:structural molecule activity; IEA. DR InterPro; IPR001664; IF. DR InterPro; IPR002957; Keratin_I. DR InterPro; IPR003054; Keratin_II. DR Pfam; PF00038; Filament; 1. DR PRINTS; PR01248; TYPE1KERATIN. DR PRINTS; PR01276; TYPE2KERATIN. DR PROSITE; PS00226; IF; 1. KW Coiled coil; Intermediate filament; Keratin. SQ SEQUENCE 513 AA; 56648 MW; C0552BA5B7110BB8 CRC64; MSYHSFQPGS RCGSQSFSSY SAVMPRMVTH YAVSKGPCRP GGGRGLRALG CLGSRSLCNV GFGRPRVASR CGGTLPGFGY RLGATCGPSA CITPVTINES LLVPLALEID PTVQRVKRDE KEQIKCLNNR FASFINKVRF LEQKNKLLET KWNFMQQQRC CQTNIEPILE GYISALRRQL DCVSGDRVRL ESELCSLQAA LEGYKKKYEE ELSLRPCVEN EFVALKKDVD TAFLMKADLE TNAEALVQEI DFLKSLYEEE ICLLQSQISE TSVIVKMDNS RELDVDGIIA EIKAQYDDIA SRSKAEAEAW YQCRYEELRV TAGNHCDNLR NRKNEILEMN KLIQRLQQET ENVKAQRCKL EGAIAEAEQQ GEAALNDAKC KLAGLEEALQ KAKQDMACLL KEYQEVMNSK LGLDIEIATY RRLLEGEEHR LCEGIGPVNI SVSSSKGAFL YEPCGVSMPV LSTGVLRSNG GCSIVGTGEL YVPCEPQGLL SCGSGRKSSM TLGAGGSSPS HKH //